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CD2 [plasma membrane]
Stable Identifier
R-HSA-197795
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
T-cell surface antigen CD2 precursor, CD2_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
CD58 binds CD2 (Homo sapiens)
CD2 [plasma membrane] (Homo sapiens)
CD58:CD2 [plasma membrane] (Homo sapiens)
CD2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06729 CD2
Gene Names
CD2, SRBC
Chain
signal peptide:1-24, chain:25-351
Reference Genes
BioGPS Gene:914 CD2
COSMIC (genes):CD2 CD2
CTD Gene:914 CD2
dbSNP Gene:914 CD2
ENSEMBL:ENSG00000116824 CD2
ENSEMBL_homo_sapiens_GENE:ENSG00000116824.5 CD2
HGNC:1639 CD2
KEGG Gene (Homo sapiens):914 CD2
Monarch:914 CD2
NCBI Gene:914 CD2
OMIM:186990 CD2
Reference Transcript
RefSeq:NM_001767.4 CD2
RefSeq:NM_001328609.1 CD2
Other Identifiers
11733736_a_at
16669169
205831_PM_at
205831_at
2353670
2353671
2353672
2353675
2353676
2353681
2353685
2353686
2353687
2353688
2353689
2353690
2353691
2353692
2353693
40738_at
7904287
914
A_14_P112244
A_23_P161076
GE81066
GO:0001766
GO:0002376
GO:0005102
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005794
GO:0005886
GO:0005911
GO:0006915
GO:0007155
GO:0007166
GO:0009897
GO:0009898
GO:0009986
GO:0012501
GO:0016020
GO:0019901
GO:0023052
GO:0030101
GO:0030154
GO:0030887
GO:0030971
GO:0032729
GO:0032757
GO:0032760
GO:0032991
GO:0034113
GO:0038023
GO:0042110
GO:0042267
GO:0042802
GO:0043226
GO:0043621
GO:0045580
GO:0048856
GO:0060089
GO:0061024
GO:0098542
GO:0098609
HMNXSV003009623
ILMN_1695025
M16336_s_at
PH_hs_0004986
TC01001022.hg
g4502652_3p_at
Participates
as a component of
CD58:CD2 [plasma membrane] (Homo sapiens)
as an input of
CD58 binds CD2 (Homo sapiens)
Inferred To
CD2 [plasma membrane]
(Bos taurus)
CD2 [plasma membrane]
(Canis familiaris)
CD2 [plasma membrane]
(Gallus gallus)
CD2 [plasma membrane]
(Sus scrofa)
Cd2 [plasma membrane]
(Mus musculus)
Cd2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001315538.1
,
NP_001758.2
Guide to Pharmacology - Targets
2600
OpenTargets
ENSG00000116824
HPA
ENSG00000116824-CD2
GeneCards
P06729
ZINC target
P06729
Ensembl
ENSP00000358490
,
ENST00000369478
,
ENSG00000116824
PRO
P06729
Pharos - Targets
P06729
PDB
1GYA
,
1CDB
,
1QA9
,
1HNF
,
1L2Z
,
2J7I
,
2J6O
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95400 CD2BP2
1
CD2BP2 [nucleoplasm]
(R-HSA-72054)
0.931
14
UniProt:Q9Y5K6 CD2AP
1
CD2AP [cytosol]
(R-HSA-373620)
0.802
6
UniProt:O43586 PSTPIP1
1
PSTPIP1 [cytosol]
(R-HSA-879220)
0.741
6
UniProt:Q96B97 SH3KBP1
3
SH3KBP1 [plasma membrane]
(R-HSA-182955)
SH3KBP1 [cytosol]
(R-HSA-182957)
Ub-SH3KBP1 [cytosol]
(R-HSA-182926)
0.618
3
UniProt:P06241 FYN
6
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-Y420-FYN [cytosol]
(R-HSA-391821)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
FYN [cytosol]
(R-HSA-200917)
0.572
3
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