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CAND1 [ficolin-1-rich granule lumen]
Stable Identifier
R-HSA-6801399
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ficolin-1-rich granule lumen
Synonyms
Cullin-associated NEDD8-dissociated protein 1, CAND1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
CAND1 [ficolin-1-rich granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86VP6 CAND1
Gene Names
CAND1, KIAA0829, TIP120, TIP120A
Chain
initiator methionine:, chain:2-1230
Reference Genes
BioGPS Gene:55832 CAND1
COSMIC (genes):CAND1 CAND1
CTD Gene:55832 CAND1
dbSNP Gene:55832 CAND1
ENSEMBL:ENSG00000111530 CAND1
ENSEMBL_homo_sapiens_GENE:ENSG00000111530.13 CAND1
HGNC:30688 CAND1
KEGG Gene (Homo sapiens):55832 CAND1
Monarch:55832 CAND1
NCBI Gene:55832 CAND1
OMIM:607727 CAND1
UCSC:Q86VP6 CAND1
Reference Transcript
RefSeq:NM_018448.4 CAND1
Other Identifiers
11719937_a_at
11719938_s_at
11719939_a_at
16753712
207483_PM_s_at
207483_s_at
208838_PM_at
208838_at
208839_PM_s_at
208839_s_at
235224_PM_s_at
235224_s_at
243910_PM_x_at
243910_x_at
32196_at
3420716
3420717
3420718
3420719
3420720
3420721
3420727
3420734
3420736
3420737
3420738
3420739
3420740
3420741
3420742
3420744
3420745
3420746
3420747
3420750
3420753
3420754
3420755
3420757
3420758
3420759
3420760
3420761
3420762
3420764
3420766
3420768
3420770
3420772
3420774
55832
59523_at
7956910
86969_at
88937_at
A_14_P135815
A_23_P25137
A_23_P25141
A_24_P47681
A_32_P150418
A_32_P232237
GE62226
GE82377
GE893252
GO:0000151
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005794
GO:0005829
GO:0006351
GO:0006355
GO:0010265
GO:0016020
GO:0016567
GO:0017025
GO:0030154
GO:0031410
GO:0031461
GO:0034774
GO:0036211
GO:0043086
GO:0043226
GO:0045893
GO:0045899
GO:0065003
GO:0070062
GO:1904813
HMNXSV003013627
HMNXSV003015307
Hs.128521.0.S1_3p_at
Hs.209521.0.A1_3p_at
ILMN_1744647
PH_hs_0026787
TC12000595.hg
TC12002426.hg
g12053130_3p_a_at
g8924259_3p_s_at
Participates
as a member of
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
Other forms of this molecule
CAND1 [cytosol]
CAND1 [extracellular region]
CAND1 [secretory granule lumen]
CAND1 [nucleoplasm]
Inferred To
Cand1 [ficolin-1-rich granule lumen]
(Drosophila melanogaster)
Cand1 [ficolin-1-rich granule lumen]
(Mus musculus)
Cand1 [ficolin-1-rich granule lumen]
(Rattus norvegicus)
knd1 [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
CAND1 [ficolin-1-rich granule lumen]
(Bos taurus)
CAND1 [ficolin-1-rich granule lumen]
(Canis familiaris)
CAND1 [ficolin-1-rich granule lumen]
(Gallus gallus)
CAND1 [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
CAND1 [ficolin-1-rich granule lumen]
(Sus scrofa)
cand1 [ficolin-1-rich granule lumen]
(Danio rerio)
cand1 [ficolin-1-rich granule lumen]
(Dictyostelium discoideum)
cand1 [ficolin-1-rich granule lumen]
(Xenopus tropicalis)
cand-1 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
Homologues of CAND1 [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_060918.2
OpenTargets
ENSG00000111530
GeneCards
Q86VP6
HPA
ENSG00000111530-CAND1
Ensembl
ENSP00000442318
,
ENSG00000111530
,
ENST00000545606
PRO
Q86VP6
Pharos - Targets
Q86VP6
PDB
8OR2
,
8CDJ
,
7ZBZ
,
8CDK
,
1U6G
,
8OR3
,
7Z8R
,
8H3Q
,
4A0C
,
8OR4
,
7Z8T
,
8OR0
,
7ZBW
,
7Z8V
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13616 CUL1
3
G76-NEDD8-K720-CUL1 [cytosol]
(R-HSA-8952519)
CUL1 [nucleoplasm]
(R-HSA-187551)
CUL1 [cytosol]
(R-HSA-174230)
0.956
33
UniProt:Q13620 CUL4B
2
CUL4B [nucleoplasm]
(R-HSA-975973)
G76-NEDD8-K859-CUL4B [nucleoplasm]
(R-HSA-8952522)
0.793
13
UniProt:Q13618 CUL3
3
G76-NEDD8-K712-CUL3 [cytosol]
(R-HSA-8952516)
CUL3 [nucleoplasm]
(R-HSA-5635033)
CUL3 [cytosol]
(R-HSA-975979)
0.748
8
UniProt:Q13619 CUL4A
2
CUL4A [nucleoplasm]
(R-HSA-976006)
G76-NEDD8-K705-CUL4A [nucleoplasm]
(R-HSA-8952514)
0.723
6
UniProt:P62877 RBX1
2
RBX1 [nucleoplasm]
(R-HSA-1234142)
RBX1 [cytosol]
(R-HSA-180582)
0.708
10
UniProt:Q13617 CUL2
3
G76-NEDD8-K689-CUL2 [cytosol]
(R-HSA-8952511)
CUL2 [nucleoplasm]
(R-HSA-1234126)
CUL2 [cytosol]
(R-HSA-416982)
0.641
3
UniProt:P46776 RPL27A
3
3OHH39-RPL27A [nucleoplasm]
(R-HSA-9630970)
RPL27A [nucleoplasm]
(R-HSA-9630984)
RPL27A [cytosol]
(R-HSA-72442)
0.564
2
UniProt:Q14627 IL13RA2
1
IL13RA2 [extracellular region]
(R-HSA-449666)
0.527
2
UniProt:Q93034 CUL5
2
CUL5 [cytosol]
(R-HSA-180528)
G76-NEDD8-K724-CUL5 [cytosol]
(R-HSA-8952014)
0.527
9
UniProt:Q92804 TAF15
1
TAF15 [nucleoplasm]
(R-HSA-9020680)
0.483
2
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE
0.462
2
ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE
0.462
2
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