Reactome | NDUFA8 [mitochondrial inner membrane]

NDUFA8 [mitochondrial inner membrane]

Stable Identifier

R-HSA-60627

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase 19 kDa subunit , Complex I-19KD, CI-19KD, Complex I-PGIV, CI-PGIV

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P51970 NDUFA8

Gene Names

NDUFA8

Chain

initiator methionine:, chain:2-172

Reference Genes

BioGPS Gene:4702 NDUFA8

COSMIC (genes):NDUFA8 NDUFA8

CTD Gene:4702 NDUFA8

dbSNP Gene:4702 NDUFA8

ENSEMBL:ENSG00000119421 NDUFA8

HGNC:7692 NDUFA8

KEGG:hsa:4702 NDUFA8

Monarch:4702 NDUFA8

NCBI Gene:4702 NDUFA8

OMIM:603359 NDUFA8

UCSC:P51970 NDUFA8

Reference Transcript

RefSeq:NM_014222.2 NDUFA8

Other Identifiers

11716205_a_at

17098071

218160_PM_at

218160_at

3224198

3224199

3224200

3224203

3224205

3224208

3224209

43795_s_at

4702

8163930

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005758

GO:0006091

GO:0006120

GO:0008137

GO:0009060

GO:0016491

GO:0032981

GO:0042776

GO:0043226

GO:0044877

GO:0045271

GO:0055085

GO:0055086

GO:0065003

GO:1901135

GO:1902600

HMNXSV003027189

ILMN_1759729

PH_hs_0002682

PH_hs_0031138

TC09001554.hg

g7657368_3p_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ND-19 [mitochondrial inner membrane] (Drosophila melanogaster)

Ndufa8 [mitochondrial inner membrane] (Mus musculus)

Ndufa8 [mitochondrial inner membrane] (Rattus norvegicus)

NDUFA8 [mitochondrial inner membrane] (Bos taurus)

NDUFA8 [mitochondrial inner membrane] (Canis familiaris)

NDUFA8 [mitochondrial inner membrane] (Gallus gallus)

NDUFA8 [mitochondrial inner membrane] (Sus scrofa)

ndua-8 [mitochondrial inner membrane] (Caenorhabditis elegans)

ndufa8 [mitochondrial inner membrane] (Danio rerio)

ndufa8 [mitochondrial inner membrane] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000373768, ENSP00000362873, ENSG00000119421

OpenTargets

ENSG00000119421

GeneCards

NDUFA8

HPA

ENSG00000119421-NDUFA8

PRO

P51970

Pharos - Targets

P51970

GlyGen

P51970

HMDB Protein

HMDBP00130

PDB

5XTI, 5XTH, 5XTD, 5XTC

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.564	5
UniProt:O43181 NDUFS4	1	NDUFS4 [mitochondrial inner membrane] (R-HSA-163946)	0.527	2
UniProt:Q9BQ95 ECSIT	2	ECSIT [cytosol] (R-HSA-168064) ECSIT [mitochondrial inner membrane] (R-HSA-5689047)	0.527	2
UniProt:P03886 MT-ND1	1	MT-ND1 [mitochondrial inner membrane] (R-HSA-60551)	0.527	2
UniProt:P03905 MT-ND4	1	MT-ND4 [mitochondrial inner membrane] (R-HSA-60561)	0.527	2
UniProt:O95139 NDUFB6	1	NDUFB6 [mitochondrial inner membrane] (R-HSA-59938)	0.527	2
UniProt:Q9UI09 NDUFA12	1	NDUFA12 [mitochondrial inner membrane] (R-HSA-59864)	0.527	2
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.527	3
UniProt:P03915 MT-ND5	1	MT-ND5 [mitochondrial inner membrane] (R-HSA-60565)	0.527	2
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.527	2