Reactome | NDUFA8 [mitochondrial inner membrane]

NDUFA8 [mitochondrial inner membrane]

Stable Identifier

R-DME-60627

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial inner membrane

Synonyms

Q9W125

Locations in the PathwayBrowser

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Metabolism (Drosophila melanogaster)

- The citric acid (TCA) cycle and respiratory electron transport (Drosophila melanogaster)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Drosophila melanogaster)
    - Respiratory electron transport (Drosophila melanogaster)
      - Complex I biogenesis (Drosophila melanogaster)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        HP subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        HP subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Drosophila melanogaster)
        
        550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        HP subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        815kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        550kDa complex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        HP subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Drosophila melanogaster)
        
        Complex I [mitochondrial inner membrane] (Drosophila melanogaster)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Drosophila melanogaster)
        
        HP subcomplex [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Homologues of NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        NDUFA8 [mitochondrial inner membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9W125

Reference Genes

BioGPS Gene:37946

dbSNP Gene:37946

ENSEMBL:FBgn0035046

Flybase:FBgn0035046

KEGG Gene (Drosophila melanogaster):Dmel_CG3683

Monarch:37946

NCBI Gene:37946

UCSC:Q9W125

Reference Transcript

Other Identifiers

147881_at

1634417_s_at

7227.FBpp0072233

AAF47252.1

AAM68324.1

AAM68325.1

ACZ94568.1

AY071332

B3DML8

CAL26709.1

CAL26710.1

CAL26711.1

CAL26712.1

CAL26713.1

CAL26714.1

CAL26715.1

CAL26716.1

CAL26717.1

CAL26718.1

CAL26719.1

CAL26720.1

CAR93780.1

CAR93781.1

CAR93782.1

CAR93783.1

CAR93784.1

CAR93785.1

CAR93786.1

CAR93787.1

CAR93788.1

CAR93789.1

CAR93790.1

CAR93791.1

EntrezGene:37946

FBgn0035046

FBpp0072231

FBpp0072232

FBpp0072233

FBpp0290258

FBtr0072324

FBtr0072325

FBtr0072326

FBtr0301036

GO:0003674

GO:0003954

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005739

GO:0005743

GO:0005747

GO:0006091

GO:0006120

GO:0008150

GO:0016020

GO:0016491

GO:0032991

GO:0034641

GO:0043226

GO:0044281

GO:0055114

GO:0070469

IPR010625

IPR016680

NM_001103974.3

NM_001169825.2

NM_138109.3

NM_138110.4

NM_138111.4

NM_166680.3

NM_166681.2

NP_001163296.1

NP_611954.2

NP_726470.1

NP_726471.1

PF06747

Q8SY88

UPI000000724D

Participant Of

hasMember

Homologues of NDUFA8 [mitochondrial inner membrane]

Inferred From

NDUFA8 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_726471.1, NP_611954.2, NP_726470.1, NP_001163296.1

Flybase

FBgn0035046