Reactome | NDUFA8 [mitochondrial inner membrane]

NDUFA8

Stable Identifier

R-XTR-60627

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

mitochondrial inner membrane

Synonyms

A4IHB3

Locations in the PathwayBrowser

Expand all

Metabolism (Xenopus tropicalis)

- The citric acid (TCA) cycle and respiratory electron transport (Xenopus tropicalis)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Xenopus tropicalis)
    - Respiratory electron transport (Xenopus tropicalis)
      - Complex I biogenesis (Xenopus tropicalis)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Xenopus tropicalis)
        
        550kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        815kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        550kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Xenopus tropicalis)
        
        815kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        550kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        980kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        815kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        550kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        550kDa complex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        315kDa subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Xenopus tropicalis)
        
        Complex I [mitochondrial inner membrane] (Xenopus tropicalis)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Xenopus tropicalis)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Xenopus tropicalis)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Xenopus tropicalis)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Xenopus tropicalis)
        
        HP subcomplex [mitochondrial inner membrane] (Xenopus tropicalis)
        
        NDUFA8 [mitochondrial inner membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A4IHB3

Reference Genes

BioGPS Gene:100125113

dbSNP Gene:100125113

ENSEMBL:ENSXETG00000016324

KEGG Gene (Xenopus tropicalis):xtr:100125113

Monarch:100125113

NCBI Gene:100125113

Reference Transcript

RefSeq:NM_001103021.1

Other Identifiers

100125113

AAI35450

AAMC01111249

BC135449

ENSXETG00000016324

ENSXETP00000035620

ENSXETT00000035620

EntrezGene:100125113

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005739

GO:0005743

GO:0005747

GO:0006091

GO:0006120

GO:0008150

GO:0016020

GO:0034641

GO:0043226

GO:0043234

GO:0044281

GO:0055114

GO:0070469

IPR010625

ndufa8

ndufa8-201

NM_001103021

NP_001096491

PF06747

Str.21838

Str.21838.1.S1_at

UPI00006A14EF

XB-GENE-979564

Participant Of

hasComponent

HP subcomplex [mitochondrial inner membrane]

Inferred From

NDUFA8 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001096491.1