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F8(582-640)
Stable Identifier
R-HSA-5607008
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Common Pathway of Fibrin Clot Formation (Homo sapiens)
Activated protein C cleaves factor VIIIa (Homo sapiens)
F8(582-640) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P00451 F8
Gene Names
F8, F8C
Chain
signal peptide:1-19, chain:20-2351, chain:20-1332, chain:20-759, chain:760-1332, chain:1668-2351
Reference Genes
BioGPS Gene:2157 F8
COSMIC (genes):F8 F8
CTD Gene:2157 F8
dbSNP Gene:2157 F8
ENSEMBL:ENSG00000185010 F8
HGNC:3546 F8
KEGG Gene (Homo sapiens):hsa:2157 F8
Monarch:2157 F8
NCBI Gene:2157 F8
OMIM:300841 F8
UCSC:P00451 F8
Reference Transcript
RefSeq:NM_019863.2 F8
RefSeq:NM_000132.3 F8
Other Identifiers
0002690746
0003140338
0004200086
11722979_a_at
11722980_a_at
11752341_a_at
17115729
18777
1CFG
1D7P
1FAC
1IQD
205756_s_at
2157
2R7E
37550_at
3CDZ
3HNB
3HNY
3HOB
3J2Q
3J2S
4027640
4027641
4027642
4027643
4027644
4027645
4027646
4027648
4027649
4027650
4027651
4027652
4027659
4027660
4027661
4027662
4027663
4027664
4027665
4027666
4027667
4027668
4027669
4027670
4027672
4027674
4027675
4027676
4027677
4027678
4027680
4027681
4027682
4027683
4027686
4027689
4027690
4027691
4BDV
4KI5
4PT6
4XZU
5K8D
8176193
A_23_P217643
A_24_P314451
CAB018777
CCDS35457
CCDS44026
ENSG00000185010
ENSP00000327895
ENSP00000353393
ENST00000330287
ENST00000360256
EntrezGene:2157
F8
F8-201
F8-202
g10518504_3p_a_at
GE57825
GO:0000139
GO:0002576
GO:0005507
GO:0005515
GO:0005576
GO:0005615
GO:0005788
GO:0005886
GO:0006888
GO:0006953
GO:0007596
GO:0007597
GO:0007599
GO:0016491
GO:0030134
GO:0030168
GO:0031093
GO:0033116
GO:0046872
GO:0048208
GO:0055114
HGNC:3546
Hs.654450
ILMN_1670229
ILMN_1675083
ILMN_1691584
ILMN_2370622
ILMN_3233263
M14113_at
MIM:300841
MIM:306700
NM_000132
NM_019863
NP_000123
NP_063916
PF00394
PF00754
PF07731
PF07732
PH_hs_0024930
SM00231
TC0X001547.hg
uc004fms.4
uc004fmt.4
UPI000006FF7B
UPI000012A416
Participant Of
output
Activated protein C cleaves factor VIIIa
Other forms of this molecule
F8(373-581) [extracellular region]
F8(20-355) [extracellular region]
F8(356-372) [extracellular region]
Factor VIII precursor [extracellular region]
Coagulation factor VIII precursor [platelet alpha granule lumen]
factor VIIIa A3 C1 C2 polypeptide [extracellular region]
factor VIIIa A2 polypeptide [extracellular region]
factor VIIIa A1 polypeptide [extracellular region]
factor VIIIa B A3 acidic polypeptide [extracellular region]
factor VIII light chain [extracellular region]
factor VIII heavy chain [extracellular region]
factor VIIIa A1 polypeptide [plasma membrane]
factor VIIIa A3 C1 C2 polypeptide [plasma membrane]
factor VIIIa A2 polypeptide [plasma membrane]
Factor VIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
Factor VIII precursor [COPII-coated ER to Golgi transport vesicle]
Factor VIII precursor [endoplasmic reticulum lumen]
Inferred To
F8(582-640) [extracellular region] (Bos taurus)
F8(582-640) [extracellular region] (Canis familiaris)
F8(582-640) [extracellular region] (Danio rerio)
F8(582-640) [extracellular region] (Gallus gallus)
F8(582-640) [extracellular region] (Mus musculus)
F8(582-640) [extracellular region] (Rattus norvegicus)
F8(582-640) [extracellular region] (Sus scrofa)
F8(582-640) [extracellular region] (Taeniopygia guttata)
F8(582-640) [extracellular region] (Xenopus tropicalis)
Homologues of F8(582-640) [extracellular region] (Danio rerio)
Cross References
RefSeq
NP_063916.1
,
NP_000123.1
GeneCards
P00451
ZINC - Substances
FA8_HUMAN
DOCK Blaster
4XZU
,
3HNB
,
1D7P
,
3CDZ
,
4PT6
,
4BDV
,
2R7E
,
3HNY
,
3HOB
,
4KI5
,
1IQD
ZINC target
P00451
PRO
P00451
ZINC - Predictions - Purchasable
FA8_HUMAN
Orphanet
16016
HMDB Protein
HMDBP01727
PDB
3HNY
,
3HOB
,
5K8D
,
3HNB
,
4XZU
,
3CDZ
,
4PT6
,
2R7E
,
4KI5
,
1IQD
,
4BDV
,
1FAC
,
1D7P
,
3J2S
,
3J2Q
,
1CFG
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