VWF H1786D (764-2813) [extracellular region]

Stable Identifier
R-HSA-9823634
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
vWF H1786D, von Willebrand factor
VWF H1786D (764-2813) [extracellular region] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
20345715 Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD

Montgomery, RR, Christopherson, PA, Friedman, KD, Hoffmann, RG, Flood, VH, Lederman, CA, Wren, JS

J Thromb Haemost 2010
External Reference Information
External Reference
Gene Names
VWF, F8VWF
Chain
signal peptide:1-22, chain:23-763, chain:764-2813
Participates
Other forms of this molecule
Modified Residues
Name
L-histidine 1786 replaced with L-aspartic acid
Coordinate
1786
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-aspartic acid.
A protein modification that effectively removes or replaces an L-histidine.
Disease
Name Identifier Synonyms
blood platelet disease DOID:2218 platelet disorder, Thrombocytopathy
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04275 VWF  20 0.868 21
 UniProt:Q76LX8 ADAMTS13  7 0.789 19
 UniProt:P00451 F8  20 0.623 2
 UniProt:P07359 GP1BA  6 0.623 2
 UniProt:P00451-PRO_0000002967 F8      0.544 2
 UniProt:Q96CV9 OPTN  6 0.454 2
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