OSulf-6Y-FVIII precursor [Golgi lumen]

Stable Identifier
R-HSA-9668036
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Icon
OSulf-6Y-FVIII precursor [Golgi lumen] icon
OSulf-6Y-FVIII precursor [Golgi lumen] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P00451 F8
Gene Names
F8, F8C
Chain
signal peptide:1-19, chain:20-2351, chain:20-1332, chain:20-759, chain:760-1332, chain:1668-2351
Reference Genes
COSMIC (genes):F8 F8
dbSNP Gene:2157 F8
ENSEMBL:ENSG00000185010 F8
Participates
as an output of
Other forms of this molecule
Factor VIII precursor [extracellular region]
Coagulation factor VIII precursor [platelet alpha granule lumen]
F8(392-759) D579A [plasma membrane]
F8(392-759) V578A [plasma membrane]
F8(392-759) R546W [plasma membrane]
F8(392-759) S577F [plasma membrane]
F8(392-759) I585T [plasma membrane]
F8 N637S [endoplasmic reticulum lumen]
F8 G2013R [endoplasmic reticulum lumen]
F8 W604R [endoplasmic reticulum lumen]
F8 R1126W [endoplasmic reticulum lumen]
F8 R2326L [endoplasmic reticulum lumen]
F8 P947R [endoplasmic reticulum lumen]
F8 H1066Y [endoplasmic reticulum lumen]
F8 S603G [endoplasmic reticulum lumen]
F8 E1057K [endoplasmic reticulum lumen]
F8 E600D [endoplasmic reticulum lumen]
F8 W604C [endoplasmic reticulum lumen]
F8 D845E [endoplasmic reticulum lumen]
F8 G720S [endoplasmic reticulum lumen]
F8 E600Q [endoplasmic reticulum lumen]
F8 R2326Q [endoplasmic reticulum lumen]
F8 R602G [endoplasmic reticulum lumen]
F8 A1610S [endoplasmic reticulum lumen]
F8 D599H [endoplasmic reticulum lumen]
F8 S603T [endoplasmic reticulum lumen]
F8 V2144_Y2351delinsHGVLENGKNWEPSYRW [endoplasmic reticulum lumen]
F8 R1329H [endoplasmic reticulum lumen]
F8 N601K [endoplasmic reticulum lumen]
F8 R2016W [endoplasmic reticulum lumen]
F8 L1481P [endoplasmic reticulum lumen]
F8 S603R [endoplasmic reticulum lumen]
F8 M633T [endoplasmic reticulum lumen]
F8 N1941S [endoplasmic reticulum lumen]
F8 A488T [endoplasmic reticulum lumen]
F8 R612C [endoplasmic reticulum lumen]
F8 D337N [endoplasmic reticulum lumen]
F8 A20_M2143delinsMRIQDPGK [endoplasmic reticulum lumen]
F8 D599V [endoplasmic reticulum lumen]
F8 N2137Q [endoplasmic reticulum lumen]
F8 E600K [endoplasmic reticulum lumen]
F8 N601D [endoplasmic reticulum lumen]
F8 N601H [endoplasmic reticulum lumen]
F8 C348S [endoplasmic reticulum lumen]
F8 S603C [endoplasmic reticulum lumen]
F8 A488S [endoplasmic reticulum lumen]
F8 N1941D [endoplasmic reticulum lumen]
F8 G1967D [endoplasmic reticulum lumen]
F8 P2067L [endoplasmic reticulum lumen]
F8 G720D [endoplasmic reticulum lumen]
F8 P2162L [endoplasmic reticulum lumen]
F8 M633I [endoplasmic reticulum lumen]
F8 C348R [endoplasmic reticulum lumen]
F8 R2178C [extracellular region]
F8 I2117S [extracellular region]
F8 P2319S [extracellular region]
F8 P2319L [extracellular region]
F8 P1828L [extracellular region]
F8 R2323H [extracellular region]
F8 S2138Y [extracellular region]
F8 R2169H [extracellular region]
F8 Y1699F [extracellular region]
F8 S2192I [extracellular region]
F8 Q2106E [extracellular region]
F8 R2326Q [extracellular region]
F8 Q2330P [extracellular region]
F8 A2220P [extracellular region]
F8 A2220del [extracellular region]
F8 R1708C [extracellular region]
F8 R1708H [extracellular region]
F8 R391C [extracellular region]
F8 R391H [extracellular region]
factor VIIIa A2 polypeptide [plasma membrane]
factor VIIIa A3 C1 C2 polypeptide [plasma membrane]
factor VIIIa A1 polypeptide [plasma membrane]
factor VIII heavy chain [extracellular region]
factor VIII light chain [extracellular region]
factor VIIIa B A3 acidic polypeptide [extracellular region]
factor VIIIa A1 polypeptide [extracellular region]
factor VIIIa A2 polypeptide [extracellular region]
factor VIIIa A3 C1 C2 polypeptide [extracellular region]
Factor VIII precursor [endoplasmic reticulum lumen]
Factor VIII precursor [COPII-coated ER to Golgi transport vesicle]
Factor VIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
F8(20-391) A303E [extracellular region]
F8(20-391) S308L [extracellular region]
F8(392-759) R550C [extracellular region]
F8(392-759) R717W [extracellular region]
F8(392-759) R717L [extracellular region]
F8(392-759) R550H [extracellular region]
F8(392-759) R550G [extracellular region]
F8(392-759) N713I [extracellular region]
F8(356-372) [extracellular region]
F8(582-640) [extracellular region]
F8(20-355) [extracellular region]
F8(373-581) [extracellular region]
F8 Y1699F [Golgi lumen]
Factor VIII precursor [Golgi lumen]
F8 Y365C [extracellular region]
F8 S392L [extracellular region]
Inferred To
OSulf-6Y-FVIII precursor [Golgi lumen] (Gallus gallus)
F8 [Golgi lumen] (Bos taurus)
F8 [Golgi lumen] (Mus musculus)
F8 [Golgi lumen] (Rattus norvegicus)
Modified Residues
Name
O4'-sulfo-L-tyrosine at 1699
Coordinate
1699
PsiMod Name
O4'-sulfo-L-tyrosine
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine.
Name
O4'-sulfo-L-tyrosine at 365
Coordinate
365
PsiMod Name
O4'-sulfo-L-tyrosine
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine.
Name
O4'-sulfo-L-tyrosine at 1683
Coordinate
1683
PsiMod Name
O4'-sulfo-L-tyrosine
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine.
Name
O4'-sulfo-L-tyrosine at 737
Coordinate
737
PsiMod Name
O4'-sulfo-L-tyrosine
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine.
Name
O4'-sulfo-L-tyrosine at 738
Coordinate
738
PsiMod Name
O4'-sulfo-L-tyrosine
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine.
Name
O4'-sulfo-L-tyrosine at 742
Coordinate
742
PsiMod Name
O4'-sulfo-L-tyrosine
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine.
Interactors (1)
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