F8(20-355) [extracellular region]

Stable Identifier
R-HSA-5607046
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Icon
F8(20-355) [extracellular region] icon
F8(20-355) [extracellular region] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P00451 F8
Gene Names
F8, F8C
Chain
signal peptide:1-19, chain:20-2351, chain:20-1332, chain:20-759, chain:760-1332, chain:1668-2351
Reference Genes
BioGPS Gene:2157 F8
COSMIC (genes):F8 F8
CTD Gene:2157 F8
dbSNP Gene:2157 F8
ENSEMBL:ENSG00000185010 F8
HGNC:3546 F8
KEGG Gene (Homo sapiens):2157 F8
Monarch:2157 F8
NCBI Gene:2157 F8
OMIM:300841 F8
UCSC:P00451 F8
Reference Transcript
Other Identifiers
0002690746
0003140338
0004200086
11722979_a_at
11722980_a_at
11752341_a_at
17115729
205756_s_at
2157
37550_at
4027640
4027641
4027642
4027643
4027644
4027645
4027646
4027648
4027649
4027650
4027651
4027652
4027659
4027660
4027661
4027662
4027663
4027664
4027665
4027666
4027667
4027668
4027669
4027670
4027672
4027674
4027675
4027676
4027677
4027678
4027680
4027681
4027682
4027683
4027686
4027689
4027690
4027691
8176193
A_23_P217643
A_24_P314451
GE57825
GO:0002576
GO:0003674
GO:0005507
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0005886
GO:0006810
GO:0006888
GO:0006950
GO:0006953
GO:0007596
GO:0007597
GO:0007599
GO:0008150
GO:0016192
GO:0016491
GO:0022607
GO:0030134
GO:0031093
GO:0031410
GO:0033116
GO:0043167
GO:0043226
GO:0046872
GO:0048208
GO:0055114
GO:0061024
GO:0065003
GO:2000267
HMNXSV003018712
ILMN_1670229
ILMN_1675083
ILMN_1691584
ILMN_2370622
ILMN_3233263
M14113_at
PH_hs_0024930
TC0X001547.hg
g10518504_3p_a_at
Participates
as a component of
Other forms of this molecule
Factor VIII precursor [extracellular region]
Coagulation factor VIII precursor [platelet alpha granule lumen]
F8(392-759) D579A [plasma membrane]
F8(392-759) V578A [plasma membrane]
F8(392-759) R546W [plasma membrane]
F8(392-759) S577F [plasma membrane]
F8(392-759) I585T [plasma membrane]
F8 N637S [endoplasmic reticulum lumen]
F8 G2013R [endoplasmic reticulum lumen]
F8 W604R [endoplasmic reticulum lumen]
F8 R1126W [endoplasmic reticulum lumen]
F8 R2326L [endoplasmic reticulum lumen]
F8 P947R [endoplasmic reticulum lumen]
F8 H1066Y [endoplasmic reticulum lumen]
F8 S603G [endoplasmic reticulum lumen]
F8 E1057K [endoplasmic reticulum lumen]
F8 E600D [endoplasmic reticulum lumen]
F8 W604C [endoplasmic reticulum lumen]
F8 D845E [endoplasmic reticulum lumen]
F8 G720S [endoplasmic reticulum lumen]
F8 E600Q [endoplasmic reticulum lumen]
F8 R2326Q [endoplasmic reticulum lumen]
F8 R602G [endoplasmic reticulum lumen]
F8 A1610S [endoplasmic reticulum lumen]
F8 D599H [endoplasmic reticulum lumen]
F8 S603T [endoplasmic reticulum lumen]
F8 V2144_Y2351delinsHGVLENGKNWEPSYRW [endoplasmic reticulum lumen]
F8 R1329H [endoplasmic reticulum lumen]
F8 N601K [endoplasmic reticulum lumen]
F8 R2016W [endoplasmic reticulum lumen]
F8 L1481P [endoplasmic reticulum lumen]
F8 S603R [endoplasmic reticulum lumen]
F8 M633T [endoplasmic reticulum lumen]
F8 N1941S [endoplasmic reticulum lumen]
F8 A488T [endoplasmic reticulum lumen]
F8 R612C [endoplasmic reticulum lumen]
F8 D337N [endoplasmic reticulum lumen]
F8 A20_M2143delinsMRIQDPGK [endoplasmic reticulum lumen]
F8 D599V [endoplasmic reticulum lumen]
F8 N2137Q [endoplasmic reticulum lumen]
F8 E600K [endoplasmic reticulum lumen]
F8 N601D [endoplasmic reticulum lumen]
F8 N601H [endoplasmic reticulum lumen]
F8 C348S [endoplasmic reticulum lumen]
F8 S603C [endoplasmic reticulum lumen]
F8 A488S [endoplasmic reticulum lumen]
F8 N1941D [endoplasmic reticulum lumen]
F8 G1967D [endoplasmic reticulum lumen]
F8 P2067L [endoplasmic reticulum lumen]
F8 G720D [endoplasmic reticulum lumen]
F8 P2162L [endoplasmic reticulum lumen]
F8 M633I [endoplasmic reticulum lumen]
F8 C348R [endoplasmic reticulum lumen]
F8 R2178C [extracellular region]
F8 I2117S [extracellular region]
F8 P2319S [extracellular region]
F8 P2319L [extracellular region]
F8 P1828L [extracellular region]
F8 R2323H [extracellular region]
F8 S2138Y [extracellular region]
F8 R2169H [extracellular region]
F8 Y1699F [extracellular region]
F8 S2192I [extracellular region]
F8 Q2106E [extracellular region]
F8 R2326Q [extracellular region]
F8 Q2330P [extracellular region]
F8 A2220P [extracellular region]
F8 A2220del [extracellular region]
F8 R1708C [extracellular region]
F8 R1708H [extracellular region]
F8 R391C [extracellular region]
F8 R391H [extracellular region]
F8 S392L [extracellular region]
F8 Y365C [extracellular region]
OSulf-6Y-FVIII precursor [Golgi lumen]
Factor VIII precursor [Golgi lumen]
F8 Y1699F [Golgi lumen]
F8(373-581) [extracellular region]
F8(582-640) [extracellular region]
F8(356-372) [extracellular region]
F8(392-759) N713I [extracellular region]
F8(392-759) R550G [extracellular region]
F8(392-759) R550H [extracellular region]
F8(392-759) R717L [extracellular region]
F8(392-759) R717W [extracellular region]
F8(392-759) R550C [extracellular region]
F8(20-391) S308L [extracellular region]
F8(20-391) A303E [extracellular region]
factor VIIIa A3 C1 C2 polypeptide [extracellular region]
factor VIIIa A2 polypeptide [extracellular region]
factor VIIIa A1 polypeptide [extracellular region]
factor VIIIa B A3 acidic polypeptide [extracellular region]
factor VIII light chain [extracellular region]
factor VIII heavy chain [extracellular region]
factor VIIIa A1 polypeptide [plasma membrane]
factor VIIIa A3 C1 C2 polypeptide [plasma membrane]
factor VIIIa A2 polypeptide [plasma membrane]
Factor VIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
Factor VIII precursor [COPII-coated ER to Golgi transport vesicle]
Factor VIII precursor [endoplasmic reticulum lumen]
Inferred To
F8(20-355) [extracellular region] (Xenopus tropicalis)
F8 [extracellular region] (Bos taurus)
F8 [extracellular region] (Gallus gallus)
F8 [extracellular region] (Mus musculus)
F8 [extracellular region] (Rattus norvegicus)
f8 [extracellular region] (Danio rerio)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
GeneCards
HPA
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (1)
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