4SUMO2,3-BLM [nucleoplasm]

Stable Identifier
R-HSA-4568883
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Bloom syndrome protein ecNumber3.6.4.12/ecNumber, BLM_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
25218447 Uncovering global SUMOylation signaling networks in a site-specific manner

Yang, B, Hendriks, IA, Verlaan-de Vries, M, Vertegaal, AC, D'Souza, RC, Mann, M

Nat. Struct. Mol. Biol. 2014
External Reference Information
External Reference
Gene Names
BLM, RECQ2, RECQL3
Chain
chain:1-1417
Other Identifiers
11756409_a_at
1544_at
16804902
205733_PM_at
205733_at
3608314
3608318
3608321
3608322
3608323
3608324
3608326
3608327
3608329
3608331
3608332
3608333
3608335
3608336
3608338
3608339
3608340
3608341
3608342
3608345
3608346
3608347
3608349
3608351
3608352
3608353
3608354
3608356
3608359
3608360
3608364
3608365
3608366
641
7986068
A_14_P114565
A_23_P88630
GE62452
GO:0000079
GO:0000166
GO:0000228
GO:0000278
GO:0000400
GO:0000403
GO:0000405
GO:0000723
GO:0000724
GO:0000729
GO:0000781
GO:0000800
GO:0002039
GO:0003676
GO:0003677
GO:0003678
GO:0003697
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005730
GO:0005737
GO:0005829
GO:0006260
GO:0006268
GO:0006281
GO:0006310
GO:0006351
GO:0006355
GO:0006974
GO:0007095
GO:0008094
GO:0008270
GO:0009378
GO:0010165
GO:0016363
GO:0016605
GO:0016787
GO:0016818
GO:0016887
GO:0023052
GO:0031297
GO:0031422
GO:0032200
GO:0032201
GO:0032508
GO:0032991
GO:0036211
GO:0042802
GO:0042803
GO:0043138
GO:0043226
GO:0044237
GO:0044806
GO:0045893
GO:0045910
GO:0046872
GO:0051259
GO:0051260
GO:0051782
GO:0051880
GO:0061749
GO:0061820
GO:0061821
GO:0061849
GO:0065003
GO:0071139
GO:0071479
GO:0072711
GO:0072757
GO:0090329
GO:0090656
GO:0098772
GO:0140097
GO:0140657
GO:0140677
GO:1905773
GO:1990814
HMNXSV003052925
ILMN_1709484
PH_hs_0024362
TC15000868.hg
U39817_at
g4557364_3p_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 317
Coordinate
317
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 331
Coordinate
331
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 344
Coordinate
344
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 347
Coordinate
347
Modification
polySUMO2,3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
OpenTargets
ZINC - Substances
ZINC target
PRO
IntEnz
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (20)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9H9A7 RMI1  1 0.906 15
 UniProt:Q13472 TOP3A  1 0.853 9
 UniProt:Q96E14 RMI2  1 0.723 5
 UniProt:Q15554 TERF2  2 0.691 8
 UniProt:Q9BX63 BRIP1  2 0.672 16
 UniProt:P27694 RPA1  2 0.669 4
 UniProt:Q5UIP0 RIF1  1 0.667 7
 UniProt:Q14159 SPIDR  1 0.663 11
 UniProt:Q14191 WRN  2 0.655 9
 UniProt:P15927 RPA2  2 0.643 6
 UniProt:O75771 RAD51D  1 0.639 4
 UniProt:P39748 FEN1  1 0.611 4
 UniProt:P53350 PLK1  4 0.591 4
 UniProt:P54274 TERF1  1 0.558 3
 UniProt:P42677 RPS27  2 0.544 4
 UniProt:Q9BQ15 NABP2  1 0.537 6
 UniProt:P35244 RPA3  1 0.527 2
 UniProt:Q96E14-1 RMI2      0.527 2
 UniProt:P51957 NEK4      0.508 2
 UniProt:Q9NZN9 AIPL1      0.508 2
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