Reactome | Metal ion SLC transporters

Metal ion SLC transporters

Stable Identifier

R-HSA-425410

Type

Pathway

Species

Homo sapiens

ReviewStatus

5/5

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Six SLC gene families encode proteins which mediate transport of metals. The families are SLC11, SLC30, SLC31, SLC39, SLC40 and SLC41 (He L et al, 2009; Bressler JP et al, 2007).

Literature References

PubMed ID	Title	Journal	Year
17215883	Recent progress in structure-function analyses of Nramp proton-dependent metal-ion transporters Chaloupka, R, Cellier, MF, Courville, P	Biochem Cell Biol	2006
15157936	Maintaining copper homeostasis: regulation of copper-trafficking proteins in response to copper deficiency or overload Bertinato, J, L'Abbé, MR	J Nutr Biochem	2004
12827356	The SLC31 (Ctr) copper transporter family Petris, MJ	Pflugers Arch	2004
16675045	Zinc transporters and the cellular trafficking of zinc Eide, DJ	Biochim Biophys Acta	2006
16908340	The NRAMP family of metal-ion transporters Nelson, N, Nevo, Y	Biochim Biophys Acta	2006
14530973	SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1 Mackenzie, B, Hediger, MA	Pflugers Arch	2004
17374385	Zinc fluxes and zinc transporter genes in chronic diseases Perozzi, G, Murgia, C, Devirgiliis, C, Zalewski, PD	Mutat Res	2007
19164095	Analysis and update of the human solute carrier (SLC) gene superfamily Nebert, DW, He, L, Vasiliou, K	Hum Genomics	2009
17439925	Metal transporters in intestine and brain: their involvement in metal-associated neurotoxicities Maerten, A, Kim, Y, Olivi, L, Bressler, JP, Cheong, JH, Bannon, D	Hum Exp Toxicol	2007
16825786	The copper transporter (Ctr) family of Cu+ uptake systems Mansour, NM, Saier MH, Jr, Debut, AJ, Dumay, QC	J Mol Microbiol Biotechnol	2006
12836025	The SLC40 basolateral iron transporter family (IREG1/ferroportin/MTP1) McKie, AT, Barlow, DJ	Pflugers Arch	2004
16720382	Magnesium transporters: properties, regulation and structure Maguire, ME	Front Biosci	2006
12748861	The SLC39 family of metal ion transporters Eide, DJ	Pflugers Arch	2004