Caspase-mediated cleavage of PKC theta

Stable Identifier
R-HSA-201603
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cleavage of PKCtheta by Caspase-3 induces nuclear fragmentation and lethality (Datta et al., 1997)

Literature References
PubMed ID Title Journal Year
9252332 Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis

Datta, R, Kojima, H, Yoshida, K, Kufe, D

J Biol Chem 1997
9431985 The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis

Mizuno, K, Noda, K, Araki, T, Imaoka, T, Kobayashi, Y, Akita, Y, Shimonaka, M, Kishi, S, Ohno, S

Eur J Biochem 1997
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cysteine-type endopeptidase activity of Caspase-3 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created