p-Y394-LCK

Stable Identifier
R-HSA-202308
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-Y394-LCK(1-509), Lck phosphorylated at tyrosine 394
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
2824653 Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens

Streuli, M, Hall, LR, Saga, Y, Schlossman, SF, Saito, H

J Exp Med 1987
External Reference Information
External Reference
Gene Names
LCK
Chain
initiator methionine:1, chain:2-509
Other Identifiers
0007100253
04660+2.7.10.2
11740979_x_at
11752568_a_at
11752569_x_at
11755231_a_at
11756006_x_at
16662052
1BHF
1BHH
1CWD
1CWE
1FBZ
1H92
1IJR
1KIK
1LCJ
1LCK
1LKK
1LKL
1Q68
1Q69
1QPC
1QPD
1QPE
1QPJ
1X27
204890_s_at
204891_3p_s_at
204891_s_at
2059_s_at
2328842
2328843
2328845
2328847
2328848
2328850
2328852
2328853
2328854
2328855
2328856
2328857
2328859
2328860
2328863
2328864
2328865
2328866
2328867
2IIM
2OF2
2OF4
2OFU
2OFV
2OG8
2PL0
2ZM1
2ZM4
2ZYB
33238_at
3494
3816
3932
3AC1
3AC2
3AC3
3AC4
3AC5
3AC8
3ACJ
3ACK
3AD4
3AD5
3AD6
3B2W
3BRH
3BYM
3BYO
3BYS
3BYU
3KMM
3KXZ
3LCK
3MPM
4C3F
4D8K
5MTM
5MTN
7899753
A0A0S2Z3T3
A0A0S2Z3Y8
A_23_P103361
A_33_P3382746
AAA18225
AAA59501
AAA59502
AAA59503
AAC50287
AAF34794
AAH13200
AF228313
AL121991
ALQ33619
ALQ33620
BC013200
BN000073
CAA28165
CAA28691
CAA29667
CAA31884
CAA32211
CAB003816
CAD55807
CAI22320
CAI22321
CCDS359
CH471059
EAX07542
EAX07543
EAX07546
ENSG00000182866
ENSP00000328213
ENSP00000337825
ENSP00000477713
ENST00000333070
ENST00000336890
ENST00000619559
EntrezGene:3932
g460965_3p_s_at
g4885448_3p_at
g4885448_3p_s_at
GE59664
GO:0000166
GO:0000242
GO:0001772
GO:0001784
GO:0002376
GO:0003674
GO:0004672
GO:0004713
GO:0004715
GO:0004722
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0006464
GO:0006468
GO:0006470
GO:0006629
GO:0006810
GO:0006882
GO:0006919
GO:0006950
GO:0007155
GO:0007165
GO:0007169
GO:0008022
GO:0008150
GO:0008219
GO:0008283
GO:0016020
GO:0016032
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0016791
GO:0018108
GO:0019899
GO:0019901
GO:0019903
GO:0030097
GO:0030154
GO:0030168
GO:0030217
GO:0031234
GO:0031295
GO:0038083
GO:0040011
GO:0042127
GO:0042169
GO:0042493
GO:0042592
GO:0042608
GO:0042609
GO:0042610
GO:0042802
GO:0043167
GO:0043226
GO:0043548
GO:0044403
GO:0045087
GO:0045121
GO:0046854
GO:0046934
GO:0048856
GO:0048870
GO:0050690
GO:0050852
GO:0050853
GO:0050862
GO:0050870
GO:0050900
GO:0051117
GO:0051209
GO:0051249
GO:0051897
GO:0055085
GO:0070062
GO:2001244
HGNC:6524
HPA003494
ILMN_2277426
ILMN_2279844
ILMN_2377109
IPR000719
IPR000980
IPR001245
IPR001452
IPR008266
IPR011009
IPR017441
IPR020635
IPR035749
IPR035850
IPR036028
IPR036860
KU178161
KU178162
LCK
LCK-201
LCK-202
LCK-214
M21510
M26692
M36881
MIM:153390
MIM:615758
NM_001042771
NM_005356
NP_001036236
NP_005347
PF00017
PF00018
PF07714
PH_hs_0000240
PR00109
PR00401
PR00452
Q573B4
SM00219
SM00252
SM00326
TC01000426.hg
U07236
U23852
U23852_s_at
uc001bux.3
uc001buy.4
uc001buz.4
UPI0000151F17
UPI0000169F3B
X04476
X05027
X06369
X13529
X14053
X14054
X14055
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
O4'-phospho-L-tyrosine at 394
Coordinate
394
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ZINC - World Drugs
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Metabolites
GeneCards
BRENDA (Homo sapiens)
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (36)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P08575 PTPRC  2 0.851 7
 UniProt:Q07666 KHDRBS1  3 0.835 5
 UniProt:P22575 TIP      0.815 9
 UniProt:Q9Y2R2 PTPN22  1 0.783 6
 UniProt:Q9NP31 SH2D2A  1 0.77 12
 UniProt:P22681 CBL  7 0.75 4
 UniProt:P43405 SYK  6 0.748 8
 UniProt:P06239 LCK  4 0.719 5
 UniProt:P43403 ZAP70  3 0.702 3
 UniProt:P01730 CD4  4 0.702 3
 UniProt:Q9H204 MED28  1 0.691 4
 UniProt:Q12959 DLG1  2 0.656 3
 UniProt:P29350 PTPN6  5 0.623 5
 UniProt:P20963 CD247      0.609 2
 UniProt:P08921 CD2      0.602 11
 UniProt:P20749 BCL3      0.591 3
 UniProt:Q13094 LCP2  2 0.564 2
 IntAct:EBI-7111687 TIP      0.558 2
 UniProt:P23771 GATA3  2 0.556 3
 UniProt:Q5VV42 CDKAL1  1 0.556 3
 UniProt:Q9BRK4 LZTS2      0.556 3
 UniProt:O60880 SH2D1A  1 0.547 2
 UniProt:P0CG48 UBC  316 0.544 2
 UniProt:Q63767 BCAR1      0.532 3
 UniProt:Q8N1K5-1 THEMIS      0.525 3
 UniProt:O43561 LAT  3 0.525 2
 UniProt:Q13283 G3BP1      0.524 2
 UniProt:P08238 HSP90AB1  5 0.524 2
 UniProt:Q13444 ADAM15  1 0.524 3
 UniProt:P28482 MAPK1  7 0.524 2
 UniProt:Q04759 PRKCQ  9 0.499 2
 UniProt:P40763-2 STAT3      0.488 2
 UniProt:O60496 DOK2  1 0.488 2
 UniProt:P32577  2 0.482 2
 UniProt:P04150 NR3C1  3 0.463 3
 UniProt:Q8TDQ0 HAVCR2  1 0.462 2