Reactome | Cellular responses to stress

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Cellular responses to stress Show undefined attributes

authored	[InstanceEdit:2262746] Matthews, L, 2012-05-20
created	[InstanceEdit:2262746] Matthews, L, 2012-05-20
dbId	2262752
deleted	[Deleted:9632607] Deletion of instance: 2262749
displayName	Cellular responses to stress
edited	[InstanceEdit:2262750] Matthews, L, 2012-05-20
eventOf	[TopLevelPathway:R-HSA-8953897] Cellular responses to stimuli - Homo sapiens
figure	[Figure:9628886] /figures/ehld/R-HSA-2262752.svg
goBiologicalProcess	[GO_BiologicalProcess:258408] cellular response to stress
hasDiagram	true
hasEHLD	true
hasEvent	[Pathway:R-HSA-1234174] Cellular response to hypoxia - Homo sapiens [Pathway:R-HSA-3371556] Cellular response to heat stress - Homo sapiens [Pathway:R-HSA-2559583] Cellular Senescence - Homo sapiens [Pathway:R-HSA-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand - Homo sapiens [Pathway:R-HSA-9648895] Response of EIF2AK1 (HRI) to heme deficiency - Homo sapiens [Pathway:R-HSA-9707616] Heme signaling - Homo sapiens [Pathway:R-HSA-9711123] Cellular response to chemical stress - Homo sapiens [Pathway:R-HSA-9711097] Cellular response to starvation - Homo sapiens [Pathway:R-HSA-381119] Unfolded Protein Response (UPR) - Homo sapiens [Pathway:R-HSA-9840373] Cellular response to mitochondrial stress - Homo sapiens [Pathway:R-HSA-9841251] Mitochondrial unfolded protein response (UPRmt) - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-09-13
literatureReference	[LiteratureReference:2265563] Molecular and evolutionary basis of the cellular stress response
maxDepth	6
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Cellular responses to stress
orthologousEvent	[Pathway:R-MMU-2262752] Cellular responses to stress - Mus musculus [Pathway:R-RNO-2262752] Cellular responses to stress - Rattus norvegicus [Pathway:R-CFA-2262752] Cellular responses to stress - Canis familiaris [Pathway:R-BTA-2262752] Cellular responses to stress - Bos taurus [Pathway:R-SSC-2262752] Cellular responses to stress - Sus scrofa [Pathway:R-DRE-2262752] Cellular responses to stress - Danio rerio [Pathway:R-XTR-2262752] Cellular responses to stress - Xenopus tropicalis [Pathway:R-GGA-2262752] Cellular responses to stress - Gallus gallus [Pathway:R-DME-2262752] Cellular responses to stress - Drosophila melanogaster [Pathway:R-CEL-2262752] Cellular responses to stress - Caenorhabditis elegans [Pathway:R-DDI-2262752] Cellular responses to stress - Dictyostelium discoideum [Pathway:R-SPO-2262752] Cellular responses to stress - Schizosaccharomyces pombe [Pathway:R-SCE-2262752] Cellular responses to stress - Saccharomyces cerevisiae [Pathway:R-PFA-2262752] Cellular responses to stress - Plasmodium falciparum
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2262747] D'Eustachio, P, 2012-05-20 [InstanceEdit:9863300] Matthews, Lisa, 2024-02-28
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-2262752
summation	[Summation:2265564] Cells are subject to external molecular and physical stresse...
updateTrackers	[UpdateTracker:9776614] Update Tracker - [Pathway:2262752] Cellular responses to stress - v75:[updateContainedPathway] [UpdateTracker:9784538] Update Tracker - [Pathway:2262752] Cellular responses to stress - v54:[updateContainedPathway] [UpdateTracker:9842230] Update Tracker - [Pathway:2262752] Cellular responses to stress - v86:[updateContainedPathway] [UpdateTracker:9785334] Update Tracker - [Pathway:2262752] Cellular responses to stress - v52:[updateContainedPathway] [UpdateTracker:9919331] Update Tracker - [Pathway:2262752] Cellular responses to stress - v90:[removeHasEvent] [UpdateTracker:9774684] Update Tracker - [Pathway:2262752] Cellular responses to stress - v81:[updateContainedPathway] [UpdateTracker:9777789] Update Tracker - [Pathway:2262752] Cellular responses to stress - v69:[updateContainedPathway] [UpdateTracker:9776842] Update Tracker - [Pathway:2262752] Cellular responses to stress - v74:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777413] Update Tracker - [Pathway:2262752] Cellular responses to stress - v71:[addHasEvent] [UpdateTracker:9853200] Update Tracker - [Pathway:2262752] Cellular responses to stress - v87:[addHasEvent] [UpdateTracker:9776329] Update Tracker - [Pathway:2262752] Cellular responses to stress - v76:[add_removeHasEvent] [UpdateTracker:9776181] Update Tracker - [Pathway:2262752] Cellular responses to stress - v77:[addHasEvent, modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9784627] Update Tracker - [Pathway:2262752] Cellular responses to stress - v53:[addHasEvent, updateContainedPathway] [UpdateTracker:9846930] Update Tracker - [Pathway:2262752] Cellular responses to stress - v83:[updateContainedPathway] [UpdateTracker:9786766] Update Tracker - [Pathway:2262752] Cellular responses to stress - v48:[addHasEvent] [UpdateTracker:9775854] Update Tracker - [Pathway:2262752] Cellular responses to stress - v78:[updateIndirectRLE] [UpdateTracker:9783088] Update Tracker - [Pathway:2262752] Cellular responses to stress - v57:[updateContainedPathway] [UpdateTracker:9786059] Update Tracker - [Pathway:2262752] Cellular responses to stress - v50:[updateIndirectRLE] [UpdateTracker:9782927] Update Tracker - [Pathway:2262752] Cellular responses to stress - v58:[updateContainedPathway] [UpdateTracker:9786939] Update Tracker - [Pathway:2262752] Cellular responses to stress - v47:[addHasEvent, updateContainedPathway] [UpdateTracker:9781893] Update Tracker - [Pathway:2262752] Cellular responses to stress - v60:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9780875] Update Tracker - [Pathway:2262752] Cellular responses to stress - v62:[modifyText, updateContainedPathway] [UpdateTracker:9774970] Update Tracker - [Pathway:2262752] Cellular responses to stress - v80:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777618] Update Tracker - [Pathway:2262752] Cellular responses to stress - v70:[addHasEvent, updateContainedPathway] [UpdateTracker:9778638] Update Tracker - [Pathway:2262752] Cellular responses to stress - v68:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777270] Update Tracker - [Pathway:2262752] Cellular responses to stress - v72:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9787017] Update Tracker - [Pathway:2262752] Cellular responses to stress - v46:[addHasEvent] [UpdateTracker:9782630] Update Tracker - [Pathway:2262752] Cellular responses to stress - v59:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9786363] Update Tracker - [Pathway:2262752] Cellular responses to stress - v49:[updateContainedPathway] [UpdateTracker:9835761] Update Tracker - [Pathway:2262752] Cellular responses to stress - v85:[updateContainedPathway] [UpdateTracker:9783419] Update Tracker - [Pathway:2262752] Cellular responses to stress - v56:[updateContainedPathway, updateIndirectRLE]

Referrals

(hasEvent)	[TopLevelPathway:R-HSA-8953897] Cellular responses to stimuli
(replacementInstances)	[Deleted:9632607] Deletion of instance: 2262749
(updatedInstance)	[UpdateTracker:9776614] Update Tracker - [Pathway:2262752] Cellular responses to stress - v75:[updateContainedPathway] [UpdateTracker:9784538] Update Tracker - [Pathway:2262752] Cellular responses to stress - v54:[updateContainedPathway] [UpdateTracker:9842230] Update Tracker - [Pathway:2262752] Cellular responses to stress - v86:[updateContainedPathway] [UpdateTracker:9785334] Update Tracker - [Pathway:2262752] Cellular responses to stress - v52:[updateContainedPathway] [UpdateTracker:9919331] Update Tracker - [Pathway:2262752] Cellular responses to stress - v90:[removeHasEvent] [UpdateTracker:9774684] Update Tracker - [Pathway:2262752] Cellular responses to stress - v81:[updateContainedPathway] [UpdateTracker:9777789] Update Tracker - [Pathway:2262752] Cellular responses to stress - v69:[updateContainedPathway] [UpdateTracker:9776842] Update Tracker - [Pathway:2262752] Cellular responses to stress - v74:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777413] Update Tracker - [Pathway:2262752] Cellular responses to stress - v71:[addHasEvent] [UpdateTracker:9853200] Update Tracker - [Pathway:2262752] Cellular responses to stress - v87:[addHasEvent] [UpdateTracker:9776329] Update Tracker - [Pathway:2262752] Cellular responses to stress - v76:[add_removeHasEvent] [UpdateTracker:9776181] Update Tracker - [Pathway:2262752] Cellular responses to stress - v77:[addHasEvent, modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9784627] Update Tracker - [Pathway:2262752] Cellular responses to stress - v53:[addHasEvent, updateContainedPathway] [UpdateTracker:9846930] Update Tracker - [Pathway:2262752] Cellular responses to stress - v83:[updateContainedPathway] [UpdateTracker:9786766] Update Tracker - [Pathway:2262752] Cellular responses to stress - v48:[addHasEvent] [UpdateTracker:9775854] Update Tracker - [Pathway:2262752] Cellular responses to stress - v78:[updateIndirectRLE] [UpdateTracker:9783088] Update Tracker - [Pathway:2262752] Cellular responses to stress - v57:[updateContainedPathway] [UpdateTracker:9786059] Update Tracker - [Pathway:2262752] Cellular responses to stress - v50:[updateIndirectRLE] [UpdateTracker:9782927] Update Tracker - [Pathway:2262752] Cellular responses to stress - v58:[updateContainedPathway] [UpdateTracker:9786939] Update Tracker - [Pathway:2262752] Cellular responses to stress - v47:[addHasEvent, updateContainedPathway] [UpdateTracker:9781893] Update Tracker - [Pathway:2262752] Cellular responses to stress - v60:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9780875] Update Tracker - [Pathway:2262752] Cellular responses to stress - v62:[modifyText, updateContainedPathway] [UpdateTracker:9774970] Update Tracker - [Pathway:2262752] Cellular responses to stress - v80:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777618] Update Tracker - [Pathway:2262752] Cellular responses to stress - v70:[addHasEvent, updateContainedPathway] [UpdateTracker:9778638] Update Tracker - [Pathway:2262752] Cellular responses to stress - v68:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777270] Update Tracker - [Pathway:2262752] Cellular responses to stress - v72:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9787017] Update Tracker - [Pathway:2262752] Cellular responses to stress - v46:[addHasEvent] [UpdateTracker:9782630] Update Tracker - [Pathway:2262752] Cellular responses to stress - v59:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9786363] Update Tracker - [Pathway:2262752] Cellular responses to stress - v49:[updateContainedPathway] [UpdateTracker:9835761] Update Tracker - [Pathway:2262752] Cellular responses to stress - v85:[updateContainedPathway] [UpdateTracker:9783419] Update Tracker - [Pathway:2262752] Cellular responses to stress - v56:[updateContainedPathway, updateIndirectRLE]

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