Reactome | Cellular response to chemical stress

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Cellular response to chemical stress Show undefined attributes

authored	[InstanceEdit:9707568] Stephan, Ralf, 2020-11-19
created	[InstanceEdit:9711127] Stephan, Ralf, 2021-01-13
dbId	9711123
displayName	Cellular response to chemical stress
edited	[InstanceEdit:9707568] Stephan, Ralf, 2020-11-19 [InstanceEdit:9715957] D'Eustachio, Peter, 2021-02-19
eventOf	[Pathway:R-HSA-2262752] Cellular responses to stress - Homo sapiens
figure	[Figure:9729930] /figures/ehld/R-HSA-9711123.svg
goBiologicalProcess	[GO_BiologicalProcess:9676638] cellular response to chemical stress
hasDiagram	true
hasEHLD	true
hasEvent	[Pathway:R-HSA-9755511] KEAP1-NFE2L2 pathway - Homo sapiens [Pathway:R-HSA-9707564] Cytoprotection by HMOX1 - Homo sapiens [Pathway:R-HSA-3299685] Detoxification of Reactive Oxygen Species - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-09-13
literatureReference	[LiteratureReference:9711084] Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action [LiteratureReference:9711081] Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies [LiteratureReference:9711109] Reactive Oxygen and Nitrogen Species-Induced Protein Modifications: Implication in Carcinogenesis and Anticancer Therapy [LiteratureReference:9711124] Oxidative stress, inflammation, and cancer: how are they linked? [LiteratureReference:9711091] Chemical activation of estrogen and aryl hydrocarbon receptor signaling pathways and their interaction in toxicology and metabolism [LiteratureReference:9711105] Comparative analysis of perturbed molecular pathways identified in in vitro and in vivo toxicology studies [LiteratureReference:9708926] Cytoprotective role of heme oxygenase-1 and heme degradation derived end products in liver injury [LiteratureReference:9708949] Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
maxDepth	5
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Cellular response to chemical stress
orthologousEvent	[Pathway:R-PFA-9711123] Cellular response to chemical stress - Plasmodium falciparum [Pathway:R-SCE-9711123] Cellular response to chemical stress - Saccharomyces cerevisiae [Pathway:R-SPO-9711123] Cellular response to chemical stress - Schizosaccharomyces pombe [Pathway:R-DDI-9711123] Cellular response to chemical stress - Dictyostelium discoideum [Pathway:R-CEL-9711123] Cellular response to chemical stress - Caenorhabditis elegans [Pathway:R-DME-9711123] Cellular response to chemical stress - Drosophila melanogaster [Pathway:R-GGA-9711123] Cellular response to chemical stress - Gallus gallus [Pathway:R-XTR-9711123] Cellular response to chemical stress - Xenopus tropicalis [Pathway:R-DRE-9711123] Cellular response to chemical stress - Danio rerio [Pathway:R-SSC-9711123] Cellular response to chemical stress - Sus scrofa [Pathway:R-BTA-9711123] Cellular response to chemical stress - Bos taurus [Pathway:R-CFA-9711123] Cellular response to chemical stress - Canis familiaris [Pathway:R-RNO-9711123] Cellular response to chemical stress - Rattus norvegicus [Pathway:R-MMU-9711123] Cellular response to chemical stress - Mus musculus
releaseDate	2021-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9715957] D'Eustachio, Peter, 2021-02-19
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9711123
summation	[Summation:9711118] Cells are equipped with versatile physiological stress respo...
updateTrackers	[UpdateTracker:9910975] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v89:[updateIndirectRLE] [UpdateTracker:9842295] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v86:[updateContainedPathway] [UpdateTracker:9775130] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v80:[addHasEvent, updateContainedPathway] [UpdateTracker:9846839] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v83:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9776266] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v77:[addLiteratureReference, modifyText, updateIndirectRLE]

Referrals

(updatedInstance)

[UpdateTracker:9910975] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v89:[updateIndirectRLE]
[UpdateTracker:9842295] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v86:[updateContainedPathway]
[UpdateTracker:9775130] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v80:[addHasEvent, updateContainedPathway]
[UpdateTracker:9846839] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v83:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9776266] Update Tracker - [Pathway:9711123] Cellular response to chemical stress - v77:[addLiteratureReference, modifyText, updateIndirectRLE]

(hasEvent)

[Pathway:R-HSA-2262752] Cellular responses to stress

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