Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
TopLevelPathway
>
Entries
Cellular responses to stimuli
Show undefined attributes
Go to Details
authored
[InstanceEdit:8953895] D'Eustachio, Peter, 2016-12-30
created
[InstanceEdit:8953894] D'Eustachio, Peter, 2016-12-30
dbId
8953897
displayName
Cellular responses to stimuli
edited
[InstanceEdit:8953895] D'Eustachio, Peter, 2016-12-30
figure
[Figure:9628951] /figures/ehld/R-HSA-8953897.svg
goBiologicalProcess
[GO_BiologicalProcess:171571] cellular response to stimulus
hasDiagram
true
hasEHLD
true
hasEvent
[Pathway:R-HSA-5660526] Response to metal ions - Homo sapiens
[Pathway:R-HSA-2262752] Cellular responses to stress - Homo sapiens
[Pathway:R-HSA-9855142] Cellular responses to mechanical stimuli - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2023-06-07
literatureReference
[LiteratureReference:2265563] Molecular and evolutionary basis of the cellular stress response
maxDepth
7
modified
[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
Cellular responses to stimuli
orthologousEvent
[TopLevelPathway:R-PFA-8953897] Cellular responses to stimuli - Plasmodium falciparum
[TopLevelPathway:R-SCE-8953897] Cellular responses to stimuli - Saccharomyces cerevisiae
[TopLevelPathway:R-SPO-8953897] Cellular responses to stimuli - Schizosaccharomyces pombe
[TopLevelPathway:R-DDI-8953897] Cellular responses to stimuli - Dictyostelium discoideum
[TopLevelPathway:R-CEL-8953897] Cellular responses to stimuli - Caenorhabditis elegans
[TopLevelPathway:R-DME-8953897] Cellular responses to stimuli - Drosophila melanogaster
[TopLevelPathway:R-GGA-8953897] Cellular responses to stimuli - Gallus gallus
[TopLevelPathway:R-XTR-8953897] Cellular responses to stimuli - Xenopus tropicalis
[TopLevelPathway:R-DRE-8953897] Cellular responses to stimuli - Danio rerio
[TopLevelPathway:R-SSC-8953897] Cellular responses to stimuli - Sus scrofa
[TopLevelPathway:R-BTA-8953897] Cellular responses to stimuli - Bos taurus
[TopLevelPathway:R-CFA-8953897] Cellular responses to stimuli - Canis familiaris
[TopLevelPathway:R-RNO-8953897] Cellular responses to stimuli - Rattus norvegicus
[TopLevelPathway:R-MMU-8953897] Cellular responses to stimuli - Mus musculus
previousReviewStatus
[ReviewStatus:9821384] two stars
releaseDate
2017-03-27
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:6798577] Atrian, Sílvia, 2015-09-19
[InstanceEdit:2262747] D'Eustachio, P, 2012-05-20
[InstanceEdit:6793656] Klionsky, Daniel J, 2015-09-03
[InstanceEdit:5693008] Tooze, Sharon A, 2015-05-13
[InstanceEdit:9919280] Matthews, Lisa, 2024-08-20
schemaClass
TopLevelPathway
species
[Species:48887] Homo sapiens
stId
R-HSA-8953897
summation
[Summation:8953896] Individual cells detect and respond to diverse external mole...
updateTrackers
[UpdateTracker:9853281] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v87:[updateContainedPathway]
[UpdateTracker:9780655] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v62:[modifyText, updateContainedPathway]
[UpdateTracker:9776460] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v76:[updateContainedPathway]
[UpdateTracker:9775117] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v80:[updateContainedPathway]
[UpdateTracker:9777482] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v71:[updateContainedPathway]
[UpdateTracker:9780497] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v63:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9835739] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v85:[updateContainedPathway]
[UpdateTracker:9774719] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v81:[updateContainedPathway]
[UpdateTracker:9777387] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v72:[updateContainedPathway]
[UpdateTracker:9776102] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v77:[updateContainedPathway]
[UpdateTracker:9777579] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v70:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9779217] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v66:[updateIndirectRLE]
[UpdateTracker:9778144] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v68:[updateContainedPathway]
[UpdateTracker:9776513] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v75:[updateContainedPathway]
[UpdateTracker:9919357] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v90:[removeHasEvent]
[UpdateTracker:9776825] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v74:[updateContainedPathway]
Referrals
(updatedInstance)
[UpdateTracker:9853281] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v87:[updateContainedPathway]
[UpdateTracker:9780655] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v62:[modifyText, updateContainedPathway]
[UpdateTracker:9776460] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v76:[updateContainedPathway]
[UpdateTracker:9775117] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v80:[updateContainedPathway]
[UpdateTracker:9777482] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v71:[updateContainedPathway]
[UpdateTracker:9780497] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v63:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9835739] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v85:[updateContainedPathway]
[UpdateTracker:9774719] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v81:[updateContainedPathway]
[UpdateTracker:9777387] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v72:[updateContainedPathway]
[UpdateTracker:9776102] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v77:[updateContainedPathway]
[UpdateTracker:9777579] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v70:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9779217] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v66:[updateIndirectRLE]
[UpdateTracker:9778144] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v68:[updateContainedPathway]
[UpdateTracker:9776513] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v75:[updateContainedPathway]
[UpdateTracker:9919357] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v90:[removeHasEvent]
[UpdateTracker:9776825] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v74:[updateContainedPathway]
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
