Reactome | Cellular response to heat stress

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Cellular response to heat stress Show undefined attributes

authored	[InstanceEdit:4793943] Shamovsky, V, 2013-10-28
created	[InstanceEdit:3371552] Shamovsky, V, 2013-05-13
dbId	3371556
displayName	Cellular response to heat stress
doi	10.3180/REACT_200819.1
edited	[InstanceEdit:5324627] Shamovsky, V, 2014-02-17
eventOf	[Pathway:R-HSA-2262752] Cellular responses to stress - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:376592] cellular response to heat
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-3371511] HSF1 activation - Homo sapiens [Pathway:R-HSA-3371571] HSF1-dependent transactivation - Homo sapiens [Pathway:R-HSA-3371453] Regulation of HSF1-mediated heat shock response - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-09-30
literatureReference	[LiteratureReference:4793704] Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress [LiteratureReference:4793691] Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Cellular response to heat stress
orthologousEvent	[Pathway:R-PFA-3371556] Cellular response to heat stress - Plasmodium falciparum [Pathway:R-SCE-3371556] Cellular response to heat stress - Saccharomyces cerevisiae [Pathway:R-SPO-3371556] Cellular response to heat stress - Schizosaccharomyces pombe [Pathway:R-DDI-3371556] Cellular response to heat stress - Dictyostelium discoideum [Pathway:R-CEL-3371556] Cellular response to heat stress - Caenorhabditis elegans [Pathway:R-DME-3371556] Cellular response to heat stress - Drosophila melanogaster [Pathway:R-GGA-3371556] Cellular response to heat stress - Gallus gallus [Pathway:R-XTR-3371556] Cellular response to heat stress - Xenopus tropicalis [Pathway:R-DRE-3371556] Cellular response to heat stress - Danio rerio [Pathway:R-SSC-3371556] Cellular response to heat stress - Sus scrofa [Pathway:R-BTA-3371556] Cellular response to heat stress - Bos taurus [Pathway:R-CFA-3371556] Cellular response to heat stress - Canis familiaris [Pathway:R-RNO-3371556] Cellular response to heat stress - Rattus norvegicus [Pathway:R-MMU-3371556] Cellular response to heat stress - Mus musculus
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5324628] Pani, Bibhusita, 2014-02-17
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-3371556
summation	[Summation:5096503] In response to exposure to elevated temperature and certain ...
updateTrackers	[UpdateTracker:9784939] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v52:[updateContainedPathway] [UpdateTracker:9786269] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v50:[updateIndirectRLE] [UpdateTracker:9779011] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v66:[updateIndirectRLE] [UpdateTracker:9786353] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v49:[updateContainedPathway, updateIndirectRLE]

Referrals

(updatedInstance)

[UpdateTracker:9784939] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v52:[updateContainedPathway]
[UpdateTracker:9786269] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v50:[updateIndirectRLE]
[UpdateTracker:9779011] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v66:[updateIndirectRLE]
[UpdateTracker:9786353] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v49:[updateContainedPathway, updateIndirectRLE]

(hasEvent)

[Pathway:R-HSA-2262752] Cellular responses to stress

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