Reactome | CDP-ETA and DAG are converted to PE by CEPT1/EPT1

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CDP-ETA and DAG are converted to PE by CEPT1/EPT1 Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1500586] ethanolaminephosphotransferase activity of CEPT1/EPT1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482967] Williams, MG, 2011-08-12
dbId	1482962
displayName	CDP-ETA and DAG are converted to PE by CEPT1/EPT1
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483213] Synthesis of PE - Homo sapiens
followingEvent	[Reaction:R-HSA-1483089] PE is converted to PS by PTDSS2 - Homo sapiens [Reaction:R-HSA-1483174] PE is methylated to PC by PEMT - Homo sapiens [Reaction:R-HSA-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] - Homo sapiens [Reaction:R-HSA-1482892] PE is hydrolyzed to 2-acyl LPE by PLA2G4C - Homo sapiens [Reaction:R-HSA-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] - Homo sapiens [Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] - Homo sapiens
input	[SimpleEntity:R-ALL-1500603] CDP-ETA [cytosol] [SimpleEntity:R-ALL-1500596] DAG [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482959] Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine [LiteratureReference:1482937] Cloning, genomic organization, and characterization of a human cholinephosphotransferase [LiteratureReference:1482954] PC and PE synthesis: mixed micellar analysis of the cholinephosphotransferase and ethanolaminephosphotransferase activities of human choline/ethanolamine phosphotransferase 1 (CEPT1) [LiteratureReference:1482958] The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity [LiteratureReference:1482951] Identification and characterization of human ethanolaminephosphotransferase1
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	CDP-ETA and DAG are converted to PE by CEPT1/EPT1
orthologousEvent	[Reaction:R-PFA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Plasmodium falciparum [Reaction:R-SCE-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Saccharomyces cerevisiae [Reaction:R-SPO-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Schizosaccharomyces pombe [Reaction:R-DDI-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Dictyostelium discoideum [Reaction:R-CEL-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Caenorhabditis elegans [Reaction:R-DME-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Drosophila melanogaster [Reaction:R-GGA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Gallus gallus [Reaction:R-XTR-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Xenopus tropicalis [Reaction:R-DRE-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Danio rerio [Reaction:R-SSC-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Sus scrofa [Reaction:R-BTA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Bos taurus [Reaction:R-CFA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Canis familiaris [Reaction:R-RNO-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Rattus norvegicus [Reaction:R-MMU-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Mus musculus
output	[SimpleEntity:R-ALL-109395] CMP [cytosol] [SimpleEntity:R-ALL-1500581] PE [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-1483190] PETA and CTP are condensed to CDP-ETA by PCY2 - Homo sapiens [Reaction:R-HSA-1483203] PA is dephosphorylated to DAG by LPIN - Homo sapiens [Reaction:R-HSA-1482777] TAG is hydrolyzed to DAG by PNPLA2/3 - Homo sapiens [Reaction:R-HSA-1482654] 2-MAG is transacylated to DAG by PNPLA2/3 - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1482962
summation	[Summation:1482910] At the endoplasmic reticulum (ER) membrane, choline/ethanola...

Referrals

(hasEvent)	[Pathway:R-HSA-1483213] Synthesis of PE
(precedingEvent)	[Reaction:R-HSA-1483174] PE is methylated to PC by PEMT [Reaction:R-HSA-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] [Reaction:R-HSA-1482892] PE is hydrolyzed to 2-acyl LPE by PLA2G4C [Reaction:R-HSA-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] [Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] [Reaction:R-HSA-1483089] PE is converted to PS by PTDSS2

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