Reactome | PE is methylated to PC by PEMT

Schema > Reaction > Entries

PE is methylated to PC by PEMT Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524127] phosphatidylethanolamine N-methyltransferase activity of PEMT [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
dbId	1483174
displayName	PE is methylated to PC by PEMT
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483191] Synthesis of PC - Homo sapiens
input	3 × [SimpleEntity:R-ALL-71284] AdoMet [cytosol] [SimpleEntity:R-ALL-1500581] PE [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482729] Activity of phosphatidylethanolamine-N-methyltransferase in brain affected by Alzheimer's disease [LiteratureReference:1483169] The methylation of phosphatidylethanolamine [LiteratureReference:1483131] Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	PE is methylated to PC by PEMT
orthologousEvent	[Reaction:R-SCE-1483174] PE is methylated to PC by PEMT - Saccharomyces cerevisiae [Reaction:R-SPO-1483174] PE is methylated to PC by PEMT - Schizosaccharomyces pombe [Reaction:R-DDI-1483174] PE is methylated to PC by PEMT - Dictyostelium discoideum [Reaction:R-GGA-1483174] PE is methylated to PC by PEMT - Gallus gallus [Reaction:R-XTR-1483174] PE is methylated to PC by PEMT - Xenopus tropicalis [Reaction:R-DRE-1483174] PE is methylated to PC by PEMT - Danio rerio [Reaction:R-SSC-1483174] PE is methylated to PC by PEMT - Sus scrofa [Reaction:R-BTA-1483174] PE is methylated to PC by PEMT - Bos taurus [Reaction:R-CFA-1483174] PE is methylated to PC by PEMT - Canis familiaris [Reaction:R-RNO-1483174] PE is methylated to PC by PEMT - Rattus norvegicus [Reaction:R-MMU-1483174] PE is methylated to PC by PEMT - Mus musculus
output	3 × [SimpleEntity:R-ALL-71285] AdoHcy [cytosol] [SimpleEntity:R-ALL-426925] PC [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-1483077] PE transports from the mitochondrial membrane to the ER - Homo sapiens [Reaction:R-HSA-1482667] 1-acyl LPE is acylated to PE by LPEAT - Homo sapiens [Reaction:R-HSA-1482646] 2-acyl LPE is acylated to PE by LPEAT - Homo sapiens [Reaction:R-HSA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483174
summation	[Summation:1482950] At the endoplasmic reticulum (ER) membrane, phosphatidyletha...

Referrals

(hasEvent)

[Pathway:R-HSA-1483191] Synthesis of PC

Cite Us!