Reactome | Synthesis of PE

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Synthesis of PE Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
dbId	1483213
displayName	Synthesis of PE
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483206] Glycerophospholipid biosynthesis - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:20450] phosphatidylethanolamine biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-1483222] ETA is phosphorylated to PETA by CHK/ETNK - Homo sapiens [Reaction:R-HSA-1483096] PETA is dephosphorylated to ETA by PHOSPHO1 - Homo sapiens [Reaction:R-HSA-5696415] PXLP-K278-ETNPPL tetramer hydrolyses PETA - Homo sapiens [Reaction:R-HSA-1483190] PETA and CTP are condensed to CDP-ETA by PCY2 - Homo sapiens [Reaction:R-HSA-1483203] PA is dephosphorylated to DAG by LPIN - Homo sapiens [Reaction:R-HSA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Homo sapiens [BlackBoxEvent:R-HSA-1483170] PS transports from the ER membrane to the IM membrane - Homo sapiens [Reaction:R-HSA-1483212] PS is decarboxylated to PE by PISD - Homo sapiens [Reaction:R-HSA-1483077] PE transports from the mitochondrial membrane to the ER - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-04-07
literatureReference	[LiteratureReference:1482958] The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity [LiteratureReference:1483104] Newly made phosphatidylserine and phosphatidylethanolamine are preferentially translocated between rat liver mitochondria and endoplasmic reticulum [LiteratureReference:1482865] Phospholipid synthesis in a membrane fraction associated with mitochondria
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Synthesis of PE
orthologousEvent	[Pathway:R-PFA-1483213] Synthesis of PE - Plasmodium falciparum [Pathway:R-SCE-1483213] Synthesis of PE - Saccharomyces cerevisiae [Pathway:R-SPO-1483213] Synthesis of PE - Schizosaccharomyces pombe [Pathway:R-DDI-1483213] Synthesis of PE - Dictyostelium discoideum [Pathway:R-CEL-1483213] Synthesis of PE - Caenorhabditis elegans [Pathway:R-DME-1483213] Synthesis of PE - Drosophila melanogaster [Pathway:R-GGA-1483213] Synthesis of PE - Gallus gallus [Pathway:R-XTR-1483213] Synthesis of PE - Xenopus tropicalis [Pathway:R-DRE-1483213] Synthesis of PE - Danio rerio [Pathway:R-SSC-1483213] Synthesis of PE - Sus scrofa [Pathway:R-BTA-1483213] Synthesis of PE - Bos taurus [Pathway:R-CFA-1483213] Synthesis of PE - Canis familiaris [Pathway:R-RNO-1483213] Synthesis of PE - Rattus norvegicus [Pathway:R-MMU-1483213] Synthesis of PE - Mus musculus
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2247963] Wakelam, Michael, 2012-05-14
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-1483213
summation	[Summation:1601942] De novo (Kennedy pathway) synthesis of phosphatidylet...
updateTrackers	[UpdateTracker:9784482] Update Tracker - [Pathway:1483213] Synthesis of PE - v54:[addHasEvent] [UpdateTracker:9777784] Update Tracker - [Pathway:1483213] Synthesis of PE - v69:[updateContainedRLE] [UpdateTracker:9775186] Update Tracker - [Pathway:1483213] Synthesis of PE - v80:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9784482] Update Tracker - [Pathway:1483213] Synthesis of PE - v54:[addHasEvent] [UpdateTracker:9777784] Update Tracker - [Pathway:1483213] Synthesis of PE - v69:[updateContainedRLE] [UpdateTracker:9775186] Update Tracker - [Pathway:1483213] Synthesis of PE - v80:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-1483206] Glycerophospholipid biosynthesis

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