Reactome | SUCCSA [mitochondrial matrix]

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SUCCSA [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-DRE-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Danio rerio [Reaction:R-HSA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Homo sapiens [Reaction:R-MMU-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Mus musculus [Reaction:R-RNO-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Rattus norvegicus [Reaction:R-CFA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Canis familiaris [Reaction:R-BTA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Bos taurus [Reaction:R-SSC-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Sus scrofa [Reaction:R-XTR-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Xenopus tropicalis [Reaction:R-GGA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Gallus gallus [Reaction:R-DME-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Drosophila melanogaster [Reaction:R-CEL-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Caenorhabditis elegans [Reaction:R-SPO-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Schizosaccharomyces pombe [Reaction:R-SCE-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA - Saccharomyces cerevisiae [Reaction:R-HSA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Homo sapiens [Reaction:R-MMU-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Mus musculus [Reaction:R-RNO-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Rattus norvegicus [Reaction:R-CFA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Canis familiaris [Reaction:R-BTA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Bos taurus [Reaction:R-SSC-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Sus scrofa [Reaction:R-DRE-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Danio rerio [Reaction:R-GGA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Gallus gallus [Reaction:R-DME-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Drosophila melanogaster [Reaction:R-CEL-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Caenorhabditis elegans [Reaction:R-DDI-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Dictyostelium discoideum
created	[InstanceEdit:880051] D'Eustachio, P, 2010-06-25
dbId	880046
displayName	SUCCSA [mitochondrial matrix]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9654414] D'Eustachio, Peter, 2019-07-18
name	SUCCSA succinate semialdehyde succinic semialdehyde 4-oxobutanoate
producedByEvent	[Reaction:R-DDI-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Dictyostelium discoideum [Reaction:R-CEL-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Caenorhabditis elegans [Reaction:R-DME-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Drosophila melanogaster [Reaction:R-DRE-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Danio rerio [Reaction:R-HSA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Homo sapiens [Reaction:R-MMU-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Mus musculus [Reaction:R-RNO-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Rattus norvegicus [Reaction:R-CFA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Canis familiaris [Reaction:R-BTA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Bos taurus [Reaction:R-SSC-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Sus scrofa [Reaction:R-XTR-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Xenopus tropicalis [Reaction:R-GGA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Gallus gallus [Reaction:R-DME-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Drosophila melanogaster [Reaction:R-CEL-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Caenorhabditis elegans [Reaction:R-DDI-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Dictyostelium discoideum [Reaction:R-SPO-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Schizosaccharomyces pombe [Reaction:R-SCE-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA - Saccharomyces cerevisiae [Reaction:R-HSA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Homo sapiens [Reaction:R-MMU-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Mus musculus [Reaction:R-RNO-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Rattus norvegicus [Reaction:R-CFA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Canis familiaris [Reaction:R-BTA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Bos taurus [Reaction:R-SSC-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Sus scrofa [Reaction:R-DRE-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Danio rerio [Reaction:R-GGA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Gallus gallus
referenceEntity	[ReferenceMolecule:chebi:57706] 4-oxobutanoate [ChEBI:57706]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-880046
updateTrackers	[UpdateTracker:9891572] Update Tracker - [SimpleEntity:880046] SUCCSA [mitochondrial matrix] - v52:[addName] [UpdateTracker:9900795] Update Tracker - [SimpleEntity:880046] SUCCSA [mitochondrial matrix] - v70:[addName, add_removeReferenceEntity] [UpdateTracker:9874253] Update Tracker - [SimpleEntity:880046] SUCCSA [mitochondrial matrix] - v43:[addName]

Referrals

(input)	[Reaction:R-DRE-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-HSA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-MMU-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-RNO-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-CFA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-BTA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-SSC-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-XTR-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-GGA-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-DME-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-CEL-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-SPO-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-SCE-888548] ALDH5A1 dehydrogenates SUCCSA to SUCCA [Reaction:R-HSA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-MMU-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-RNO-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-CFA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-BTA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-SSC-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-DRE-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-GGA-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-DME-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-CEL-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate [Reaction:R-DDI-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate
(output)	[Reaction:R-DDI-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-CEL-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-DME-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-DRE-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-HSA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-MMU-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-RNO-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-CFA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-BTA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-SSC-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-XTR-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-GGA-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-DME-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-CEL-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-DDI-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-SPO-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-SCE-916855] PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA [Reaction:R-HSA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-MMU-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-RNO-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-CFA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-BTA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-SSC-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-DRE-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde [Reaction:R-GGA-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde
(updatedInstance)	[UpdateTracker:9891572] Update Tracker - [SimpleEntity:880046] SUCCSA [mitochondrial matrix] - v52:[addName] [UpdateTracker:9900795] Update Tracker - [SimpleEntity:880046] SUCCSA [mitochondrial matrix] - v70:[addName, add_removeReferenceEntity] [UpdateTracker:9874253] Update Tracker - [SimpleEntity:880046] SUCCSA [mitochondrial matrix] - v43:[addName]

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