Reactome | EST17b [cytosol]

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EST17b [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-5605147] Defective CYP1B1 does not 4-hydroxylate EST17b - Homo sapiens [Reaction:R-GGA-211951] CYP1B1 4-hydroxylates EST17b - Gallus gallus [Reaction:R-DRE-211951] CYP1B1 4-hydroxylates EST17b - Danio rerio [Reaction:R-SSC-211951] CYP1B1 4-hydroxylates EST17b - Sus scrofa [Reaction:R-BTA-211951] CYP1B1 4-hydroxylates EST17b - Bos taurus [Reaction:R-CFA-211951] CYP1B1 4-hydroxylates EST17b - Canis familiaris [Reaction:R-RNO-211951] CYP1B1 4-hydroxylates EST17b - Rattus norvegicus [Reaction:R-MMU-211951] CYP1B1 4-hydroxylates EST17b - Mus musculus [Reaction:R-HSA-211951] CYP1B1 4-hydroxylates EST17b - Homo sapiens [Reaction:R-HSA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Homo sapiens [Reaction:R-MMU-5693390] HSD17B11 dehydrogenates EST17b to E1 - Mus musculus [Reaction:R-RNO-5693390] HSD17B11 dehydrogenates EST17b to E1 - Rattus norvegicus [Reaction:R-CFA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Canis familiaris [Reaction:R-BTA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Bos taurus [Reaction:R-SSC-5693390] HSD17B11 dehydrogenates EST17b to E1 - Sus scrofa [Reaction:R-XTR-5693390] HSD17B11 dehydrogenates EST17b to E1 - Xenopus tropicalis [Reaction:R-GGA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Gallus gallus [Reaction:R-DME-5693390] HSD17B11 dehydrogenates EST17b to E1 - Drosophila melanogaster [Reaction:R-CEL-5693390] HSD17B11 dehydrogenates EST17b to E1 - Caenorhabditis elegans [Reaction:R-SCE-5693390] HSD17B11 dehydrogenates EST17b to E1 - Saccharomyces cerevisiae [Reaction:R-SPO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Schizosaccharomyces pombe [Reaction:R-DME-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Drosophila melanogaster [Reaction:R-GGA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Gallus gallus [Reaction:R-XTR-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Xenopus tropicalis [Reaction:R-SSC-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Sus scrofa [Reaction:R-BTA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Bos taurus [Reaction:R-CFA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Canis familiaris [Reaction:R-RNO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Rattus norvegicus [Reaction:R-MMU-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Mus musculus [Reaction:R-HSA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Homo sapiens [Reaction:R-XTR-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Xenopus tropicalis [Reaction:R-DRE-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Danio rerio [Reaction:R-BTA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Bos taurus [Reaction:R-HSA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Homo sapiens [Reaction:R-MMU-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Mus musculus [Reaction:R-RNO-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Rattus norvegicus [Reaction:R-CFA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Canis familiaris [Reaction:R-BTA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Bos taurus [Reaction:R-SSC-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Sus scrofa [Reaction:R-DRE-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Danio rerio [Reaction:R-XTR-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Xenopus tropicalis [Reaction:R-GGA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Gallus gallus [Reaction:R-HSA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Homo sapiens [Reaction:R-MMU-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Mus musculus [Reaction:R-RNO-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Rattus norvegicus
created	[InstanceEdit:193053] Jassal, B, 2007-02-13 10:16:33
crossReference	[DatabaseIdentifier:31002] COMPOUND:C00951
dbId	193132
deleted	[Deleted:9968103] Deletion of instance: 176619
displayName	EST17b [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9619952] Wu, G, 2018-09-19
name	EST17b Estradiol-17beta 17beta-estradiol
producedByEvent	[Reaction:R-HSA-193143] CYP19A1 hydroxylates TEST to EST17b - Homo sapiens [Reaction:R-MMU-193143] CYP19A1 hydroxylates TEST to EST17b - Mus musculus [Reaction:R-RNO-193143] CYP19A1 hydroxylates TEST to EST17b - Rattus norvegicus [Reaction:R-CFA-193143] CYP19A1 hydroxylates TEST to EST17b - Canis familiaris [Reaction:R-BTA-193143] CYP19A1 hydroxylates TEST to EST17b - Bos taurus [Reaction:R-SSC-193143] CYP19A1 hydroxylates TEST to EST17b - Sus scrofa [Reaction:R-DRE-193143] CYP19A1 hydroxylates TEST to EST17b - Danio rerio [Reaction:R-XTR-193143] CYP19A1 hydroxylates TEST to EST17b - Xenopus tropicalis [Reaction:R-GGA-193143] CYP19A1 hydroxylates TEST to EST17b - Gallus gallus [Reaction:R-DME-193143] CYP19A1 hydroxylates TEST to EST17b - Drosophila melanogaster [Reaction:R-CEL-193143] CYP19A1 hydroxylates TEST to EST17b - Caenorhabditis elegans [Reaction:R-HSA-804969] HSD17B1 hydrogenates E1 to EST17b - Homo sapiens [Reaction:R-MMU-804969] HSD17B1 hydrogenates E1 to EST17b - Mus musculus [Reaction:R-RNO-804969] HSD17B1 hydrogenates E1 to EST17b - Rattus norvegicus [Reaction:R-CFA-804969] HSD17B1 hydrogenates E1 to EST17b - Canis familiaris [Reaction:R-BTA-804969] HSD17B1 hydrogenates E1 to EST17b - Bos taurus [Reaction:R-SSC-804969] HSD17B1 hydrogenates E1 to EST17b - Sus scrofa [Reaction:R-DRE-804969] HSD17B1 hydrogenates E1 to EST17b - Danio rerio [Reaction:R-XTR-804969] HSD17B1 hydrogenates E1 to EST17b - Xenopus tropicalis [Reaction:R-GGA-804969] HSD17B1 hydrogenates E1 to EST17b - Gallus gallus [Reaction:R-DDI-804969] HSD17B1 hydrogenates E1 to EST17b - Dictyostelium discoideum [Reaction:R-SPO-804969] HSD17B1 hydrogenates E1 to EST17b - Schizosaccharomyces pombe
referenceEntity	[ReferenceMolecule:chebi:16469] 17beta-estradiol [ChEBI:16469]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-193132
updateTrackers	[UpdateTracker:9873801] Update Tracker - [SimpleEntity:193132] EST17b [cytosol] - v43:[addName] [UpdateTracker:9890779] Update Tracker - [SimpleEntity:193132] EST17b [cytosol] - v52:[addName]

Referrals

(input)	[FailedReaction:R-HSA-5605147] Defective CYP1B1 does not 4-hydroxylate EST17b [Reaction:R-GGA-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-DRE-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-SSC-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-BTA-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-CFA-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-RNO-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-MMU-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-HSA-211951] CYP1B1 4-hydroxylates EST17b [Reaction:R-SPO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-DME-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-GGA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-XTR-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-SSC-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-BTA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-CFA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-RNO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-MMU-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-HSA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-XTR-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-DRE-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-BTA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-HSA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-MMU-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-RNO-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-CFA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-BTA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-SSC-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-DRE-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-XTR-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-GGA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP [Reaction:R-HSA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-MMU-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-RNO-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-CFA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-BTA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-SSC-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-XTR-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-GGA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-DME-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-CEL-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-SCE-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-HSA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-MMU-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-RNO-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1)
(output)	[Reaction:R-HSA-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-MMU-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-RNO-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-CFA-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-BTA-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-SSC-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-DRE-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-XTR-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-GGA-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-DME-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-CEL-193143] CYP19A1 hydroxylates TEST to EST17b [Reaction:R-HSA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-MMU-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-RNO-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-CFA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-BTA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-SSC-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-DRE-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-XTR-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-GGA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-DDI-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-SPO-804969] HSD17B1 hydrogenates E1 to EST17b
(replacementInstances)	[Deleted:9968103] Deletion of instance: 176619
(updatedInstance)	[UpdateTracker:9873801] Update Tracker - [SimpleEntity:193132] EST17b [cytosol] - v43:[addName] [UpdateTracker:9890779] Update Tracker - [SimpleEntity:193132] EST17b [cytosol] - v52:[addName]

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