Reactome | beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP

Schema > Reaction > Entries

beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP Show undefined attributes

catalystActivity	[CatalystActivity:176571] steroid sulfotransferase activity of SULT1E1 dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:176534] D'Eustachio, P, 2006-03-08 20:43:01
crossReference	[DatabaseIdentifier:12668238] RHEA:52373
dbId	176521
displayName	beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
edited	[InstanceEdit:176810] D'Eustachio, P, 2006-03-11 18:40:17
eventOf	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules - Homo sapiens
followingEvent	[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Homo sapiens
input	[SimpleEntity:R-ALL-193132] EST17b [cytosol] [SimpleEntity:R-ALL-158471] PAPS [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:176663] Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
orthologousEvent	[Reaction:R-GGA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Gallus gallus [Reaction:R-XTR-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Xenopus tropicalis [Reaction:R-DRE-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Danio rerio [Reaction:R-SSC-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Sus scrofa [Reaction:R-BTA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Bos taurus [Reaction:R-CFA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Canis familiaris [Reaction:R-RNO-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Rattus norvegicus [Reaction:R-MMU-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Mus musculus
output	[SimpleEntity:R-ALL-176492] E2-SO4 [cytosol] [SimpleEntity:R-ALL-158466] PAP [cytosol]
precedingEvent	[Reaction:R-HSA-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54 [InstanceEdit:9968105] Hill, David P, 2025-10-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-176521
summation	[Summation:176488] Sulfonation of beta-estradiol (EST17b) is catalyzed by SULT1...
updateTrackers	[UpdateTracker:9971821] Update Tracker - [Reaction:176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - v95:[add_removeInput, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9971821] Update Tracker - [Reaction:176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - v95:[add_removeInput, modifyText]
(precedingEvent)	[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
(hasEvent)	[Pathway:R-HSA-156584] Cytosolic sulfonation of small molecules