Reactome | HSD17B11 dehydrogenates EST17b to E1

Schema > Reaction > Entries

HSD17B11 dehydrogenates EST17b to E1 Show undefined attributes

catalystActivity	[CatalystActivity:10063313] estradiol 17-beta-dehydrogenase [NAD(P)+] activity of HSD17B11 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10063315
displayName	HSD17B11 dehydrogenates EST17b to E1
eventOf	[Pathway:R-MMU-193144] Estrogen biosynthesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Homo sapiens
input	[SimpleEntity:R-ALL-193132] EST17b [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	HSD17B11 dehydrogenates EST17b to E1
output	[SimpleEntity:R-ALL-193066] E1 [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
precedingEvent	[Reaction:R-MMU-193143] CYP19A1 hydroxylates TEST to EST17b - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5693390
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-193144] Estrogen biosynthesis
(inferredTo)	[Reaction:R-HSA-5693390] HSD17B11 dehydrogenates EST17b to E1

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