Reactome | phospho-p-S473-AKT1 [plasma membrane]

phospho-p-S473-AKT1 [plasma membrane]

Stable Identifier

R-RNO-377265

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P47196

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P47196 Akt1

Gene Names

Akt1

Chain

chain:1-480

Reference Genes

BioGPS Gene:24185 Akt1

ENSEMBL:ENSRNOG00055028853 Akt1

ENSEMBL:ENSRNOG00060026743 Akt1

ENSEMBL:ENSRNOG00065028102 Akt1

KEGG Gene (Rattus norvegicus):24185 Akt1

Monarch:24185 Akt1

NCBI Gene:24185 Akt1

UCSC:P47196 Akt1

Reference Transcript

Participates

as a member of

p-S-AKT [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

phospho-p-T308,S473-AKT1 [plasma membrane]

phospho-p-Y315,Y326-AKT1 [cytosol]

phospho-p-T308-AKT1 [cytosol]

Phospho-Akt1 [nucleoplasm]

Phospho-Akt1 [cytosol]

Akt1 [cytosol]

AKT1 [plasma membrane]

phospho-p-T308,S473-AKT1 [cytosol]

phospho-p-T308,S473-AKT1 [nucleoplasm]

Inferred From

p-S473-AKT1 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 473

Coordinate

473

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_150233.1, XP_006240693.1

IntEnz

2.7.11.1

PRO

P47196

RGD

2081

HMDB Protein

HMDBP13421

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q63369 NFKB1			0.61	9
UniProt:O70436	8	Ub-SMAD2 [cytosol] (R-RNO-6782774) phospho-p-S250-SMAD2 [cytosol] (R-RNO-9731121) SMAD2 [nucleoplasm] (R-RNO-3006352) phospho-Ub,p-T220,S465,S467-SMAD2 [nucleoplasm] (R-RNO-9773843) phospho-p-T220,S465,S467-SMAD2 [nucleoplasm] (R-RNO-3009189) SMAD2 [cytosol] (R-RNO-3006353) phospho-p-S465,S467-SMAD2 [cytosol] (R-RNO-3009186) phospho-p-S465,S467-SMAD2 [nucleoplasm] (R-RNO-3009185)	0.524	2
UniProt:P84025	9	Ub-SMAD3 [cytosol] (R-RNO-6782830) phospho-p-S208-SMAD3 [cytosol] (R-RNO-9731114) SMAD3 [nucleoplasm] (R-RNO-206150) phospho-2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] (R-RNO-2187326) phospho-Ub,p-T179,S423,S425-SMAD3 [nucleoplasm] (R-RNO-9773841) phospho-p-T179,S423,S425-SMAD3 [nucleoplasm] (R-RNO-2176471) SMAD3 [cytosol] (R-RNO-170855) phospho-p-S423,S425-SMAD3 [cytosol] (R-RNO-171184) phospho-p-S423,S425-SMAD3 [nucleoplasm] (R-RNO-177104)	0.524	4