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Nfkb1 [nucleoplasm]
Stable Identifier
R-RNO-177655
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
NFKB1(1-433), Q63369
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Rattus norvegicus)
Cell junction organization (Rattus norvegicus)
Cell-cell junction organization (Rattus norvegicus)
Adherens junctions interactions (Rattus norvegicus)
Activation of STAT3 by cadherin engagement (Rattus norvegicus)
RAC1, CDC42 activate NFκB (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to mechanical stimuli (Rattus norvegicus)
Response of endothelial cells to shear stress (Rattus norvegicus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Rattus norvegicus)
PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus (Rattus norvegicus)
p-S536-RELA:NFKB1(1-433) [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Chromatin organization (Rattus norvegicus)
Chromatin modifying enzymes (Rattus norvegicus)
PKMTs methylate histone lysines (Rattus norvegicus)
SETD6 methylates RELA in the NFkB complex (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
NFkB Complex with MeK310-RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Downstream signaling events of B Cell Receptor (BCR) (Rattus norvegicus)
Activation of NF-kappaB in B cells (Rattus norvegicus)
NF-kappaB translocates from the cytosol to the nucleus (Rattus norvegicus)
NF-kappaB p50,p65,c-Rel dimer [nucleoplasm] (Rattus norvegicus)
NF-kappaB p50:c-Rel [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
NF-kappaB p50:p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
TCR signaling (Rattus norvegicus)
Downstream TCR signaling (Rattus norvegicus)
NFKB1:RELA translocates from the cytosol to the nucleus (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 processing (Rattus norvegicus)
Interleukin-1 family precursors are cleaved by caspase-1 (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
NFKB1:RELA translocates from the cytosol to the nucleus (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CD209 (DC-SIGN) signaling (Rattus norvegicus)
CBP and p300 binds NF-kB complex (Rattus norvegicus)
NFKB1:p-S276-RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276-RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276-RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
p300 acetylates RELA subunit (Rattus norvegicus)
NFKB1:p-S276,5AcK-RELA:p300/CBP [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276,5AcK-RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276-RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
CLEC7A (Dectin-1) signaling (Rattus norvegicus)
NFKB1:RELA translocates from the cytosol to the nucleus (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Cytosolic sensors of pathogen-associated DNA (Rattus norvegicus)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Rattus norvegicus)
NFkB complex translocates from the cytosol to the nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
ZBP1(DAI) mediated induction of type I IFNs (Rattus norvegicus)
RIP-mediated NFkB activation via ZBP1 (Rattus norvegicus)
NFkB complex translocates from the cytosol to the nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Rattus norvegicus)
TRAF6 mediated NF-kB activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
FCERI mediated NF-kB activation (Rattus norvegicus)
NFKB1:RELA translocates from the cytosol to the nucleus (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)
NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm] (Rattus norvegicus)
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
p75 NTR receptor-mediated signalling (Rattus norvegicus)
p75NTR signals via NF-kB (Rattus norvegicus)
NF-kB is activated and signals survival (Rattus norvegicus)
NF-kB migrates to the nucleus and turns on transcription (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
Nfkb1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q63369
Gene Names
Nfkb1
Reference Genes
BioGPS Gene:81736 Nfkb1
ENSEMBL:ENSRNOG00000023258
Monarch:81736 Nfkb1
NCBI Gene:81736 Nfkb1
UCSC:Q63369 Nfkb1
Reference Transcript
RefSeq:NM_001415012.1 Nfkb1
Participates
as a component of
p-S536-RELA:NFKB1(1-433) [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276,5AcK-RELA [nucleoplasm] (Rattus norvegicus)
NFKB1:p-S276-RELA [nucleoplasm] (Rattus norvegicus)
NF-kappaB p50:c-Rel [nucleoplasm] (Rattus norvegicus)
NF-kappaB p50:p50 [nucleoplasm] (Rattus norvegicus)
NFKB1(1-433):RELA [nucleoplasm] (Rattus norvegicus)
as a member of
Nuclear factor NF-kappa-B p50 [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
Nfkb1 [secretory granule lumen]
Nfkb1 [extracellular region]
Nfkb1 [specific granule lumen]
Nfkb1 [cytosol]
Nfkb1 [cytosol]
phospho-Nfkb1 [cytosol]
phospho-Nfkb1 [cytosol]
Inferred From
NFKB1(1-433) [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001401941.1
RGD
70498
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P47196 Akt1
11
phospho-p-S473-AKT1 [cytosol]
(R-RNO-9841264)
phospho-p-T308,S473-AKT1 [plasma membrane]
(R-RNO-199430)
phospho-p-Y315,Y326-AKT1 [cytosol]
(R-RNO-8848757)
phospho-p-T308-AKT1 [cytosol]
(R-RNO-198634)
Phospho-Akt1 [nucleoplasm]
(R-RNO-198325)
Phospho-Akt1 [cytosol]
(R-RNO-198376)
Akt1 [cytosol]
(R-RNO-437274)
AKT1 [plasma membrane]
(R-RNO-199416)
phospho-p-S473-AKT1 [plasma membrane]
(R-RNO-377265)
phospho-p-T308,S473-AKT1 [cytosol]
(R-RNO-198356)
phospho-p-T308,S473-AKT1 [nucleoplasm]
(R-RNO-198357)
0.61
9
UniProt:Q99N34
2
Dffb [cytosol]
(R-RNO-211211)
Dffb [nucleoplasm]
(R-RNO-211195)
0.544
2
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