Reactome | PPIG [nucleoplasm]

PPIG [nucleoplasm]

Stable Identifier

R-HSA-9769592

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Peptidyl-prolyl cis-trans isomerase G, PPIG_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13427 PPIG

Gene Names

PPIG

Chain

chain:1-754

Reference Genes

BioGPS Gene:9360 PPIG

COSMIC (genes):PPIG PPIG

CTD Gene:9360 PPIG

dbSNP Gene:9360 PPIG

ENSEMBL:ENSG00000138398 PPIG

ENSEMBL_homo_sapiens_GENE:ENSG00000138398.17 PPIG

HGNC:14650 PPIG

KEGG Gene (Homo sapiens):9360 PPIG

Monarch:9360 PPIG

NCBI Gene:9360 PPIG

OMIM:606093 PPIG

UCSC:Q13427 PPIG

Reference Transcript

Other Identifiers

11730267_a_at

11746095_a_at

11754211_a_at

11754212_a_at

11754213_x_at

11754214_a_at

11760261_at

16887289

208993_PM_s_at

208993_s_at

208994_PM_s_at

208994_s_at

208995_PM_s_at

208995_s_at

225902_PM_at

225902_at

2514442

2514443

2514444

2514445

2514446

2514447

2514453

2514454

2514455

2514456

2514457

2514459

2514464

2514465

2514472

2514473

2514476

2514478

2514479

2514480

2514481

2514482

2514483

2514484

2514486

2514488

2836977

2836979

37385_at

57600_at

64105_at

8046169

83394_at

9360

A_14_P134029

A_24_P179354

GE800042

GE81439

GO:0000413

GO:0003723

GO:0003755

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006457

GO:0006807

GO:0008380

GO:0016018

GO:0016363

GO:0016607

GO:0016853

GO:0036211

GO:0043170

GO:0043226

GO:0044238

GO:0140096

HMNXSV003008014

Hs.35274.0.A1_3p_at

Hs.35274.0.A1_3p_x_at

Hs.77965.0.A1_3p_a_at

Hs.77965.0.A2_3p_a_at

ILMN_1807611

ILMN_2212156

PH_hs_0004502

TC02001004.hg

TC02003678.hg

U40763_s_at

g1117967_3p_a_at

Participates

as a component of

as an input of

Formation of the Spliceosomal B* complex (Homo sapiens)

as an output of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

Other forms of this molecule

PPIG [cytosol]

Inferred To

Ghost homologue of PPIG [nucleoplasm] (Bos taurus)

Ghost homologue of PPIG [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of PPIG [nucleoplasm] (Canis familiaris)

Ghost homologue of PPIG [nucleoplasm] (Danio rerio)

Ghost homologue of PPIG [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of PPIG [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of PPIG [nucleoplasm] (Gallus gallus)

Ghost homologue of PPIG [nucleoplasm] (Mus musculus)

Ghost homologue of PPIG [nucleoplasm] (Plasmodium falciparum)

Ghost homologue of PPIG [nucleoplasm] (Rattus norvegicus)

Ghost homologue of PPIG [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of PPIG [nucleoplasm] (Sus scrofa)

Ghost homologue of PPIG [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

XP_005247023.1, NP_004783.2, XP_005247024.1

OpenTargets

ENSG00000138398

GeneCards

Q13427

HPA

ENSG00000138398-PPIG

Ensembl

ENST00000260970, ENSP00000408683, ENSP00000407083, ENSP00000435987, ENST00000678499, ENSP00000260970, ENST00000679107, ENST00000462903, ENSP00000503136, ENST00000676756, ENSP00000503525, ENST00000414307, ENSP00000502997, ENSP00000402222, ENSG00000138398, ENST00000433207, ENST00000448752

PRO

Q13427

Pharos - Targets

Q13427

HMDB Protein

HMDBP10693

PDB

5YZG, 2WFI, 2WFJ, 2GW2

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16637 SMN1	2	SMN1 [nucleoplasm] (R-HSA-191892) SMN1 [cytosol] (R-HSA-191839)	0.666	4
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.589	2
UniProt:Q8N7W2-2 BEND7			0.556	3
UniProt:P17931 LGALS3	3	LGALS3 [ficolin-1-rich granule membrane] (R-HSA-6803307) LGALS3 [secretory granule membrane] (R-HSA-6803327) LGALS3 [plasma membrane] (R-HSA-879445)	0.556	3
UniProt:Q96CD2 PPCDC	1	PPCDC [cytosol] (R-HSA-196829)	0.556	3
UniProt:Q6NVH9 Q6NVH9			0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q9NVV9 THAP1			0.556	3
UniProt:O75553 DAB1	2	DAB1 [cytosol] (R-HSA-8855236) p-Y198,220,232-DAB1 [cytosol] (R-HSA-8855227)	0.556	3
UniProt:Q12800 TFCP2			0.556	3
UniProt:Q96C98 Q96C98			0.556	3
UniProt:Q9UL42 PNMA2			0.556	3
UniProt:Q9UI36-2 DACH1			0.556	3
UniProt:Q8NC69 KCTD6	1	KCTD6 [cytosol] (R-HSA-8863321)	0.556	3
UniProt:Q14498 RBM39	1	RBM39 [nucleoplasm] (R-HSA-9770254)	0.556	3
UniProt:Q13618 CUL3	3	G76-NEDD8-K712-CUL3 [cytosol] (R-HSA-8952516) CUL3 [nucleoplasm] (R-HSA-5635033) CUL3 [cytosol] (R-HSA-975979)	0.527	2
UniProt:P0C6X7-PRO_0000037309 REP			0.508	4
UniProt:Q15365 PCBP1	1	PCBP1 [nucleoplasm] (R-HSA-71919)	0.508	2

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