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RNPS1 [nucleoplasm]
Stable Identifier
R-HSA-156778
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Transcription Termination (Homo sapiens)
Cleavage of mRNA at the 3'-end (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Homo sapiens)
NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Transport of the export-competent mRNP complex through the NPC (Homo sapiens)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
mRNA 3'-end processing (Homo sapiens)
Cleavage of mRNA at the 3'-end (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
mRNA polyadenylation (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C complex containing intron lariat (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
ASAP complex, PSAP complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
RNPS1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15287 RNPS1
Gene Names
RNPS1, LDC2
Chain
chain:1-305
Reference Genes
COSMIC (genes):RNPS1 RNPS1
dbSNP Gene:10921 RNPS1
ENSEMBL:ENSG00000205937 RNPS1
Participates
as a component of
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
ASAP complex [nucleoplasm] (Homo sapiens)
PSAP complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Other forms of this molecule
RNPS1 [cytosol]
Inferred To
RnpS1 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of RNPS1 [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of RNPS1 [nucleoplasm]
(Sus scrofa)
rnp-5 [nucleoplasm]
(Caenorhabditis elegans)
Rnps1 [nucleoplasm]
(Mus musculus)
Rnps1 [nucleoplasm]
(Rattus norvegicus)
RNPS1 [nucleoplasm]
(Bos taurus)
RNPS1 [nucleoplasm]
(Canis familiaris)
RNPS1 [nucleoplasm]
(Dictyostelium discoideum)
RNPS1 [nucleoplasm]
(Gallus gallus)
RNPS1 [nucleoplasm]
(Schizosaccharomyces pombe)
rnps1 [nucleoplasm]
(Danio rerio)
rnps1 [nucleoplasm]
(Xenopus tropicalis)
Interactors (24)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08170 SRSF4
1
SRSF4 [nucleoplasm]
(R-HSA-72024)
0.678
3
UniProt:Q13523 PRPF4B
1
PRPF4B [nucleoplasm]
(R-HSA-9769525)
0.669
4
UniProt:Q16629 SRSF7
1
SRSF7 [nucleoplasm]
(R-HSA-72029)
0.666
4
UniProt:Q07955 SRSF1
1
SRSF1 [nucleoplasm]
(R-HSA-72031)
0.665
3
UniProt:Q9BZI7 UPF3B
2
UPF3B [cytosol]
(R-HSA-159258)
UPF3B [nucleoplasm]
(R-HSA-156776)
0.643
3
UniProt:Q9Y2W1 THRAP3
1
THRAP3 [nucleoplasm]
(R-HSA-8932115)
0.589
2
UniProt:O43464 HTRA2
1
HTRA2 [mitochondrial intermembrane space]
(R-HSA-56655)
0.564
2
UniProt:Q9UJV9 DDX41
4
DDX41 [nucleoplasm]
(R-HSA-9769601)
DDX41 [cytosol]
(R-HSA-3134807)
K48polyUb-DDX41 [cytosol]
(R-HSA-3134942)
K48polyUb-DDX41 [cytosol]
(R-HSA-3134941)
0.564
2
UniProt:Q8N5F7 NKAP
1
NKAP [nucleoplasm]
(R-HSA-9769602)
0.564
3
UniProt:Q05519 SRSF11
1
SRSF11 [nucleoplasm]
(R-HSA-72058)
0.564
2
UniProt:Q92620 DHX38
1
DHX38 [nucleoplasm]
(R-HSA-72060)
0.564
2
UniProt:Q8IYB3 SRRM1
2
SRRM1 [cytosol]
(R-HSA-159255)
SRRM1 [nucleoplasm]
(R-HSA-156781)
0.564
2
UniProt:P26368 U2AF2
2
U2AF2 [nucleoplasm]
(R-HSA-71987)
5OHK15,276-U2AF2 [nucleoplasm]
(R-HSA-9630011)
0.564
4
UniProt:Q13427 PPIG
2
PPIG [nucleoplasm]
(R-HSA-9769592)
PPIG [cytosol]
(R-HSA-9728768)
0.564
3
UniProt:O94906 PRPF6
1
PRPF6 [nucleoplasm]
(R-HSA-71881)
0.564
2
UniProt:O75400 PRPF40A
1
PRPF40A [nucleoplasm]
(R-HSA-8867890)
0.564
2
UniProt:P38919 EIF4A3
2
EIF4A3 [nucleoplasm]
(R-HSA-8849149)
EIF4A3 [cytosol]
(R-HSA-927868)
0.558
4
UniProt:Q9UGI0 ZRANB1
1
ZRANB1 [cytosol]
(R-HSA-6781939)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:P84103 SRSF3
1
SRSF3 [nucleoplasm]
(R-HSA-72035)
0.556
3
UniProt:Q13242 SRSF9
1
SRSF9 [nucleoplasm]
(R-HSA-72037)
0.556
3
UniProt:Q9UKV3 ACIN1
4
ACIN1 [cytosol]
(R-HSA-212519)
ACIN1(1094-1341) [cytosol]
(R-HSA-212516)
ACIN1(1-1093) [cytosol]
(R-HSA-212520)
ACIN1 [nucleoplasm]
(R-HSA-9770238)
0.547
3
UniProt:Q13247 SRSF6
1
SRSF6 [nucleoplasm]
(R-HSA-72026)
0.547
3
UniProt:O75152 ZC3H11A
1
ZC3H11A [nucleoplasm]
(R-HSA-8850659)
0.483
2
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