Reactome | acetyl-ALB [extracellular region]

acetyl-ALB [extracellular region]

Stable Identifier

R-HSA-9749660

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

acetylated Serum albumin

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External Reference Information

External Reference

UniProt:P02768 ALB

Gene Names

ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341

Chain

signal peptide:1-18, propeptide:19-24, chain:25-609

Reference Genes

BioGPS Gene:213 ALB

COSMIC (genes):ALB ALB

CTD Gene:213 ALB

dbSNP Gene:213 ALB

ENSEMBL:ENSG00000163631.17 ALB

HGNC:399 ALB

KEGG Gene (Homo sapiens):213 ALB

Monarch:213 ALB

NCBI Gene:213 ALB

OMIM:103600 ALB

UCSC:P02768 ALB

Reference Transcript

RefSeq:NM_000477.6 ALB

Other Identifiers

0003170176

11732978_x_at

11747269_a_at

11756969_s_at

1565228_3p_s_at

1565228_PM_s_at

1565228_s_at

16967692

211298_PM_s_at

211298_s_at

213

2731193

2731194

2731195

2731198

2731199

2731201

2731202

2731206

2731207

2731209

2731211

2731212

2731214

2731218

2731220

2731223

2731225

2731227

2731228

2731229

33990_at

33991_g_at

33992_at

8095628

A_14_P110095

A_23_P257834

GE79001

GO:0001895

GO:0003677

GO:0005504

GO:0005507

GO:0005515

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005783

GO:0005788

GO:0005794

GO:0008270

GO:0008289

GO:0009267

GO:0012501

GO:0015643

GO:0016209

GO:0019825

GO:0030170

GO:0031093

GO:0031410

GO:0032991

GO:0042802

GO:0043066

GO:0043069

GO:0043226

GO:0046872

GO:0051087

GO:0051659

GO:0070062

GO:0072562

GO:0098754

GO:0098869

GO:0140272

GO:1903981

HMNXSV003004569

Hs2.406155.1.S1_3p_s_at

ILMN_1682763

ILMN_1782939

TC04000403.hg

U22961_s_at

g7959790_3p_x_at

Participates

as an output of

ASA- acetylates ALB (Homo sapiens)

Other forms of this molecule

ALB(19-609) [extracellular region]

ALB [platelet alpha granule lumen]

salicyl-ALB [extracellular region]

ALB [extracellular region]

p-ALB [endoplasmic reticulum lumen]

ALB [endoplasmic reticulum lumen]

Inferred To

ALB [extracellular region] (Sus scrofa)

acetyl-ALB [extracellular region] (Bos taurus)

acetyl-ALB [extracellular region] (Gallus gallus)

acetyl-ALB [extracellular region] (Mus musculus)

acetyl-ALB [extracellular region] (Rattus norvegicus)

acetyl-ALB [extracellular region] (Xenopus tropicalis)

Modified Residues

Name

N6-acetyl-L-lysine at 199

Coordinate

199

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Name

N6-acetyl-L-lysine at 519

Coordinate

519

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_000468.1

ZINC - World Drugs

ALBU_HUMAN

OpenTargets

ENSG00000163631

ZINC - FDA approved

ALBU_HUMAN

ZINC - Substances

ALBU_HUMAN

ZINC - Biogenic

ALBU_HUMAN

ZINC target

P02768

PRO

P02768

PDB

1GNI, 6M5D, 7EEK, 2N0X, 4IW1, 4LA0, 3JRY, 3UIV, 5UJB, 1HA2, 5Z0B, 4K71, 5YOQ, 2XVW, 4EMX, 2BXQ, 4L9Q, 7VR9, 4HGM, 2BXP, 2BXK, 2XVV, 1AO6, 3JQZ, 6YG9, 2BXN, 2BX8, 1YSX, 1H9Z, 2ESG, 2VUF, 2BXM, 3LU6, 6ZL1, 3TDL, 1HK4, 5IJF, 2BXC, 2BXE, 1TF0, 7DJN, 2I2Z, 2BXA, 7AAE, 4S1Y, 1HK3, 4Z69, 6QIP, 7D6J, 5GIX, 5GIY, 2VDB, 6XV0, 4N0U, 6M58, 2YDF, 6R7S, 6WUW, 4G03, 3LU7, 2BXG, 6M5E, 2XVQ, 5IFO, 2XW1, 3A73, 1BM0, 4N0F, 6EZQ, 2BXL, 3CX9, 2BXO, 5YB1, 3LU8, 2BXI, 7AAI, 1HK1, 1N5U, 7JWN, 6HSC, 3SQJ, 7DL4, 1E7B, 2VUE, 4IW2, 1E7F, 2BXD, 5FUO, 5X52, 4L8U, 6JE7, 4BKE, 6QIO, 1HK5, 6A7P, 1UOR, 4LB9, 3B9M, 2BXB, 6L4K, 1HK2, 2I30, 7A9C, 1E7E, 4LB2, 2XW0, 1E78, 3B9L, 2XSI, 4K2C, 1E7H, 6M4R, 1E7C, 4G04, 2XVU, 5VNW, 1E7I, 5ID7, 1E7G, 7QFE, 4L9K, 4HGK, 1E7A, 1GNJ, 4E99, 2BXF, 1O9X, 2BXH, 1BKE, 1BJ5

HPA

ENSG00000163631-ALB

GeneCards

P02768

Ensembl

ENSP00000295897, ENSP00000483421, ENST00000295897, ENST00000621085, ENSG00000163631

Pharos - Targets

P02768

ZINC - Predictions - Purchasable

ALBU_HUMAN

Orphanet

15485

HMDB Protein

HMDBP02075

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02768 ALB	7	ALB(19-609) [extracellular region] (R-HSA-114609) ALB [platelet alpha granule lumen] (R-HSA-49865) salicyl-ALB [extracellular region] (R-HSA-9750694) acetyl-ALB [extracellular region] (R-HSA-9749660) ALB [extracellular region] (R-HSA-194115) p-ALB [endoplasmic reticulum lumen] (R-HSA-8956930) ALB [endoplasmic reticulum lumen] (R-HSA-8956690)	0.758	8
UniProt:P02786 TFRC	5	TFRC(1-760) [clathrin-coated endocytic vesicle membrane] (R-HSA-8869124) TFRC(1-760) [Golgi membrane] (R-HSA-434330) TFRC(1-760) [cytoplasmic vesicle membrane] (R-HSA-434196) TFRC(1-760) [endosome membrane] (R-HSA-8961829) TFRC(1-760) [plasma membrane] (R-HSA-917983)	0.558	2
ChEBI:49786 NICKEL(2+)			0.544	4