Reactome | ALB [platelet alpha granule lumen]

ALB [platelet alpha granule lumen]

Stable Identifier

R-HSA-49865

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet alpha granule lumen

Synonyms

Serum albumin precursor

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External Reference Information

External Reference

UniProt:P02768 ALB

Gene Names

ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341

Chain

signal peptide:1-18, propeptide:19-24, chain:25-609

Reference Genes

BioGPS Gene:213 ALB

COSMIC (genes):ALB FBF1

CTD Gene:213 ALB

dbSNP Gene:213 ALB

ENSEMBL:ENSG00000163631 ALB

HGNC:399 ALB

KEGG:hsa:213 ALB

Monarch:213 ALB

NCBI Gene:213 ALB

OMIM:103600 ALB

UCSC:P02768 ALB

Reference Transcript

RefSeq:NM_000477.6 ALB

Participates

as a member of

Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)

Other forms of this molecule

ALB(19-609) [extracellular region]

ALB [endoplasmic reticulum lumen]

p-ALB [endoplasmic reticulum lumen]

ALB [extracellular region]

acetyl-ALB [extracellular region]

salicyl-ALB [extracellular region]

Inferred To

ALB [platelet alpha granule lumen] (Bos taurus)

ALB [platelet alpha granule lumen] (Canis familiaris)

ALB [platelet alpha granule lumen] (Gallus gallus)

ALB [platelet alpha granule lumen] (Mus musculus)

ALB [platelet alpha granule lumen] (Rattus norvegicus)

ALB [platelet alpha granule lumen] (Sus scrofa)

ALB [platelet alpha granule lumen] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000163631

ENSEMBL

ENSP00000295897, ENST00000295897, ENSG00000163631

ZINC - FDA approved

ALBU_HUMAN

ZINC - Substances

ALBU_HUMAN

ZINC - Biogenic

ALBU_HUMAN

ZINC target

P02768

PRO

P02768

GlyGen

P02768

PDB

4BKE, 8J8E, 2BXM, 1GNJ, 5Z0B, 5GIY, 8EW7, 7DL4, 6M58, 6M4R, 2BXG, 8RCP, 2XVU, 2I2Z, 1TF0, 5YOQ, 2BXD, 4LB9, 2XW1, 9CSG, 4L9K, 7DJN, 8ISM, 6R7S, 4G03, 8VAC, 1UOR, 2ESG, 2VDB, 8YXA, 7QFE, 1E7E, 2BXQ, 8ITR, 5UJB, 8ITT, 4HGM, 6QIO, 2BXK, 2BXH, 2BXN, 7A9C, 8K1Y, 8OI2, 1N5U, 1E7B, 7AAE, 4IW1, 7EEK, 3LU7, 1HK2, 5FUO, 4N0U, 2BXA, 2BXE, 6A7P, 4LA0, 3LU6, 3UIV, 6M5D, 7FFS, 5YB1, 2VUF, 4EMX, 8VAF, 7Z57, 1HK4, 1AO6, 3A73, 1BKE, 8RGK, 4LB2, 1E7F, 4L9Q, 2YDF, 3CX9, 3JQZ, 4E99, 7WLF, 6JE7, 6ZL1, 4HGK, 1GNI, 5GIX, 3SQJ, 1BJ5, 1HA2, 7AAI, 1H9Z, 1HK1, 2N0X, 1YSX, 7WZ9, 1HK3, 1O9X, 7JWN, 8CKS, 2BXB, 2BXF, 1E78, 7WOK, 2XVW, 8RCO, 6M5E, 6YG9, 3JRY, 4G04, 4S1Y, 6L4K, 5X52, 3B9M, 8VAE, 6EZQ, 8YXB, 2BX8, 2I30, 7VR0, 1HK5, 1E7I, 1E7C, 1E7G, 8Q3F, 5VNW, 5IFO, 6QIP, 2BXO, 2XW0, 2BXI, 1BM0, 2BXL, 7VR9, 1E7A, 8EW4, 3LU8, 7D6J, 4L8U, 4K71, 4IW2, 2BXC, 8H0O, 2XVV, 2XVQ, 6XV0, 2XSI, 7WOJ, 8EY5, 5ID7, 7Y2D, 2VUE, 8A9Q, 5IJF, 7X7X, 8Z8V, 4Z69, 4K2C, 8RGL, 4N0F, 7FFR, 1E7H, 3B9L, 2BXP, 3TDL, 7WKZ, 6WUW

HPA

ENSG00000163631-ALB

GeneCards

ALB

Pharos - Targets

P02768

Orphanet

ALB

ZINC - Predictions - Purchasable

ALBU_HUMAN

HMDB Protein

HMDBP02075

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02768 ALB	7	ALB [platelet alpha granule lumen] (R-HSA-49865) ALB(19-609) [extracellular region] (R-HSA-114609) ALB [endoplasmic reticulum lumen] (R-HSA-8956690) p-ALB [endoplasmic reticulum lumen] (R-HSA-8956930) ALB [extracellular region] (R-HSA-194115) acetyl-ALB [extracellular region] (R-HSA-9749660) salicyl-ALB [extracellular region] (R-HSA-9750694)	0.758	8
UniProt:P02786 TFRC	5	TFRC(1-760) [plasma membrane] (R-HSA-917983) TFRC(1-760) [endosome membrane] (R-HSA-8961829) TFRC(1-760) [cytoplasmic vesicle membrane] (R-HSA-434196) TFRC(1-760) [Golgi membrane] (R-HSA-434330) TFRC(1-760) [clathrin-coated endocytic vesicle membrane] (R-HSA-8869124)	0.558	2
ChEBI:49786 NICKEL(2+)			0.544	4
UniProt:Q16659 MAPK6 gene	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.527	2
UniProt:Q8TE60 ADAMTS18	4	ADAMTS18 [extracellular region] (R-HSA-3791290) ADAMTS18 [endoplasmic reticulum lumen] (R-HSA-5173116) glc-fuc-ADAMTS18 [endoplasmic reticulum lumen] (R-HSA-5173291) O-fuc-ADAMTS18 [endoplasmic reticulum lumen] (R-HSA-5173143)	0.527	2
UniProt:P35219 CAH8			0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
UniProt:Q9H8H2 DDX31			0.527	2

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