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RNF125 [cytosol]
Stable Identifier
R-HSA-918184
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RNF125, RN125_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
Negative regulators of DDX58/IFIH1 signaling (Homo sapiens)
RNF125 mediated ubiquitination of DDX58, IFIH1 and MADS (Homo sapiens)
RNF125 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96EQ8 RNF125
Gene Names
RNF125
Chain
initiator methionine:1, chain:2-232
Reference Genes
BioGPS Gene:54941 RNF125
COSMIC (genes):RNF125 RNF125
CTD Gene:54941 RNF125
dbSNP Gene:54941 RNF125
ENSEMBL:ENSG00000101695 RNF125
HGNC:21150 RNF125
KEGG Gene (Homo sapiens):54941 RNF125
Monarch:54941 RNF125
NCBI Gene:54941 RNF125
OMIM:610432 RNF125
UCSC:Q96EQ8 RNF125
Reference Transcript
RefSeq:NM_017831.3 RNF125
Other Identifiers
0003170537
11730477_at
11730478_at
16851801
207735_at
235199_at
3680640
3783725
3783731
3783732
3783735
3783736
3783739
3783741
3783742
3783744
3783746
54941
8020806
83118_at
A_23_P101141
A_33_P3257993
GO:0000139
GO:0000209
GO:0002039
GO:0002250
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005794
GO:0006464
GO:0006511
GO:0006950
GO:0007165
GO:0008150
GO:0008270
GO:0009056
GO:0016020
GO:0016567
GO:0016740
GO:0019899
GO:0031624
GO:0032480
GO:0034098
GO:0039536
GO:0043167
GO:0043226
GO:0043231
GO:0046872
GO:0061630
Hs.276860.0.S1_3p_at
Hs.276860.0.S1_3p_x_at
ILMN_1747192
PH_hs_0014229
PH_hs_0031817
TC18000132.hg
g8923428_3p_at
g8923428_3p_x_at
Participant Of
output
RNF125 mediated ubiquitination of DDX58, IFIH1 and MADS
Other forms of this molecule
K48polyUb-RNF125 [cytosol]
Cross References
RefSeq
NP_060301.2
OpenTargets
ENSG00000101695
IntEnz
2.3.2.27
HPA
ENSG00000101695-RNF125
GeneCards
Q96EQ8
Ensembl
ENSG00000101695
,
ENSP00000217740
,
ENST00000217740
PRO
Q96EQ8
Orphanet
24862
PDB
5DKA
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96LR5 UBE2E2
1
UBE2E2 [cytosol]
(R-HSA-947626)
0.674
5
UniProt:O95786-1 DDX58
0.576
5
UniProt:O14933 UBE2L6
2
UBE2L6 [cytosol]
(R-HSA-936014)
UBE2L6 [nucleoplasm]
(R-HSA-5653666)
0.488
2
UniProt:P68036 UBE2L3
4
UBE2L3 [nucleoplasm]
(R-HSA-8852056)
Ub-C86-UBE2L3 [nucleoplasm]
(R-HSA-8864226)
Ub-C86-UBE2L3 [cytosol]
(R-HSA-8864201)
UBE2L3 [cytosol]
(R-HSA-947631)
0.488
2
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