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UBE2E2 [cytosol]
Stable Identifier
R-HSA-947626
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin-conjugating enzyme E2 E2, UB2E2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Transfer of ubiquitin from E1 to E2 (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2E2 [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
15545318
Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
Plafker, KS
,
Macara, IG
,
Weissman, AM
,
Plafker, SM
J. Cell Biol.
2004
External Reference Information
External Reference
UniProt:Q96LR5 UBE2E2
Gene Names
UBE2E2, UBCH8
Chain
initiator methionine:, chain:2-201
Reference Genes
BioGPS Gene:7325 UBE2E2
COSMIC (genes):UBE2E2 UBE2E2
CTD Gene:7325 UBE2E2
dbSNP Gene:7325 UBE2E2
ENSEMBL:ENSG00000182247 UBE2E2
HGNC:12478 UBE2E2
KEGG:hsa:7325 UBE2E2
Monarch:7325 UBE2E2
NCBI Gene:7325 UBE2E2
OMIM:602163 UBE2E2
UCSC:Q96LR5 UBE2E2
Reference Transcript
RefSeq:NM_152653.3 UBE2E2
RefSeq:XM_005265432.2 UBE2E2
Other Identifiers
11719964_a_at
16938322
225651_PM_at
225651_at
2613921
2613922
2613923
2613924
2613925
2613950
2613989
2613992
2614002
2614003
2614004
2614005
2614006
2614007
2614008
42082_at
48087_at
7325
8078252
A_14_P120341
A_14_P135351
A_32_P155506
GO:0000209
GO:0003824
GO:0004842
GO:0005515
GO:0005524
GO:0005634
GO:0006974
GO:0016567
GO:0016740
GO:0019787
GO:0032020
GO:0042296
GO:0043226
GO:0061631
GO:0070534
GO:0070936
GO:0070979
GO:0140096
GO:1900087
HMNXSV003002398
HMNXSV003008695
HMNXSV003015854
HMNXSV003022298
Hs.108323.0.S1_3p_at
ILMN_1707475
PH_hs_0005240
PH_hs_0022555
TC03000121.hg
Participates
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
Inferred To
Ube2e2 [cytosol]
(Mus musculus)
Ube2e2 [cytosol]
(Rattus norvegicus)
Ubc2 [cytosol]
(Drosophila melanogaster)
UBE2E2 [cytosol]
(Bos taurus)
UBE2E2 [cytosol]
(Canis familiaris)
UBE2E2 [cytosol]
(Dictyostelium discoideum)
UBE2E2 [cytosol]
(Gallus gallus)
UBE2E2 [cytosol]
(Sus scrofa)
Dmel\CG10862 [cytosol]
(Drosophila melanogaster)
Dmel\CG5440 [cytosol]
(Drosophila melanogaster)
ubc-24 [cytosol]
(Caenorhabditis elegans)
ube2e2 [cytosol]
(Danio rerio)
Homologues of UBE2E2 [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_689866.1
,
XP_005265489.1
ENSEMBL
ENSP00000401053
,
ENST00000396703
,
ENSP00000379931
,
ENST00000425792
OpenTargets
ENSG00000182247
IntEnz
2.3.2.23
HPA
ENSG00000182247-UBE2E2
PRO
Q96LR5
Pharos - Targets
Q96LR5
GlyGen
Q96LR5
HMDB Protein
HMDBP00584
PDB
1Y6L
,
6W9A
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96EQ8 RNF125
2
RNF125 [cytosol]
(R-HSA-918184)
K48polyUb-RNF125 [cytosol]
(R-HSA-3080560)
0.674
5
UniProt:O00308 WWP2
1
WWP2 [cytosol]
(R-HSA-6807279)
0.556
3
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