UBA1 [nucleoplasm]

Stable Identifier
R-HSA-8852116
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin-like modifier-activating enzyme 1, UBA1_HUMAN
Icon
UBA1 [nucleoplasm] icon
UBA1 [nucleoplasm] icon
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
8010951 Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent

Grenfell, SJ, Trausch-Azar, JS, Handley-Gearhart, PM, Ciechanover, A, Schwartz, AL

Biochem. J. 1994
21816346 Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins

Lee, PC, Sowa, ME, Gygi, SP, Harper, JW

Mol. Cell 2011
External Reference Information
External Reference
UniProt:P22314 UBA1
Gene Names
UBA1, A1S9T, UBE1
Chain
initiator methionine:1, chain:2-1058
Reference Genes
BioGPS Gene:7317 UBA1
COSMIC (genes):UBA1 UBA1
CTD Gene:7317 UBA1
dbSNP Gene:7317 UBA1
ENSEMBL:ENSG00000130985 UBA1
HGNC:12469 UBA1
KEGG Gene (Homo sapiens):7317 UBA1
Monarch:7317 UBA1
NCBI Gene:7317 UBA1
OMIM:314370 UBA1
UCSC:P22314 UBA1
Reference Transcript
Other Identifiers
0002760711
0006380458
11715371_a_at
1268_at
1506
17103024
19435
200964_at
289
3976064
3976068
3976069
3976079
3976080
3976081
3976082
3976083
3976084
3976085
3976086
3976087
3976088
3976090
3976091
3976092
3976093
3976094
3976095
3976097
3976100
3976101
3976103
3976104
3976106
3976108
3976109
3976114
3976116
3976117
3976118
3976119
4P22
6DC6
7317
73410
8167069
A0A024R1A3
A_23_P137209
A_24_P237374
AAA61246
AAH13041
AEE61200
AL513366
BC013041
CAA37078
CAA40296
CAB019435
CAB073410
CCDS14275
CH471164
EAW59290
EAW59291
EAW59293
ENSG00000130985
ENSP00000338413
ENSP00000366568
ENST00000335972
ENST00000335972.10
ENST00000377351
ENST00000377351.8
EntrezGene:7317
EntrezGene:UBA1
g4507762_3p_at
GE57988
GO:0000166
GO:0000792
GO:0003674
GO:0003723
GO:0004839
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005739
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005829
GO:0006464
GO:0006511
GO:0006950
GO:0006974
GO:0008150
GO:0008641
GO:0009056
GO:0010008
GO:0016567
GO:0016874
GO:0030057
GO:0030867
GO:0031410
GO:0032446
GO:0043167
GO:0043226
GO:0070062
HGNC:12469
HM005603
HPA000289
HPA001506
ILMN_1683609
ILMN_1720764
ILMN_3297945
IPR000011
IPR000594
IPR018074
IPR018075
IPR018965
IPR019572
IPR032418
IPR032420
IPR033127
IPR035985
IPR038252
IPR042063
IPR042302
IPR042449
M58028
M58028_at
MIM:301830
MIM:314370
NM_003334
NM_153280
NP_003325
NP_695012
PF00899
PF09358
PF10585
PF16190
PF16191
PH_hs_0024681
PR01849
Q5JRR6
Q5JRR9
Q5JRS0
Q5JRS1
Q5JRS2
Q5JRS3
SM00985
TC0X000228.hg
UBA1
UBA1-201
UBA1-203
UBE1
UPI0000137946
X52897
X56976
XM_005272649
XM_011543954
XM_017029777
XM_017029778
XM_017029779
XM_017029780
XM_017029781
XP_005272706
XP_011542256
XP_016885266
XP_016885267
XP_016885268
XP_016885269
XP_016885270
Participant Of
input
hasComponent
Other forms of this molecule
UBA1 [cytosol]
Inferred To
UBA1 [nucleoplasm] (Bos taurus)
UBA1 [nucleoplasm] (Caenorhabditis elegans)
UBA1 [nucleoplasm] (Canis familiaris)
UBA1 [nucleoplasm] (Danio rerio)
UBA1 [nucleoplasm] (Dictyostelium discoideum)
UBA1 [nucleoplasm] (Drosophila melanogaster)
UBA1 [nucleoplasm] (Mus musculus)
UBA1 [nucleoplasm] (Plasmodium falciparum)
UBA1 [nucleoplasm] (Rattus norvegicus)
UBA1 [nucleoplasm] (Saccharomyces cerevisiae)
UBA1 [nucleoplasm] (Schizosaccharomyces pombe)
UBA1 [nucleoplasm] (Sus scrofa)
UBA1 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
Orphanet
PDB
HMDB Protein
Interactors (7)