UBA1 [nucleoplasm]

Stable Identifier
R-HSA-8852116
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin-like modifier-activating enzyme 1, UBA1_HUMAN
Icon
UBA1 [nucleoplasm] icon
UBA1 [nucleoplasm] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
21816346 Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins

Gygi, SP, Sowa, ME, Harper, JW, Lee, PC

Mol. Cell 2011
8010951 Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent

Schwartz, AL, Ciechanover, A, Grenfell, SJ, Handley-Gearhart, PM, Trausch-Azar, JS

Biochem. J. 1994
External Reference Information
External Reference
UniProt:P22314 UBA1
Gene Names
UBA1, A1S9T, UBE1
Chain
initiator methionine:1, initiator methionine:, chain:2-1058
Reference Genes
BioGPS Gene:7317 UBA1
COSMIC (genes):UBA1 UBA1
CTD Gene:7317 UBA1
dbSNP Gene:7317 UBA1
ENSEMBL:ENSG00000130985 UBA1
ENSEMBL:ENSG00000130985.17 UBA1
HGNC:12469 UBA1
KEGG Gene (Homo sapiens):7317 UBA1
Monarch:7317 UBA1
NCBI Gene:7317 UBA1
OMIM:314370 UBA1
UCSC:P22314 UBA1
Reference Transcript
Other Identifiers
11715371_a_at
1268_at
17103024
200964_PM_at
200964_at
3976064
3976068
3976069
3976079
3976080
3976081
3976082
3976083
3976084
3976085
3976086
3976087
3976088
3976090
3976091
3976092
3976093
3976094
3976095
3976097
3976100
3976101
3976103
3976104
3976106
3976108
3976109
3976114
3976116
3976117
3976118
3976119
7317
8167069
A_23_P137209
A_24_P237374
GE57988
GO:0000166
GO:0000792
GO:0003723
GO:0003824
GO:0004839
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005739
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005829
GO:0006511
GO:0006974
GO:0008641
GO:0010008
GO:0016567
GO:0016874
GO:0030057
GO:0030163
GO:0030867
GO:0031410
GO:0032446
GO:0036211
GO:0043226
GO:0070062
GO:0140096
HMNXSV003003863
ILMN_1683609
ILMN_1720764
M58028_at
PH_hs_0024681
TC0X000228.hg
g4507762_3p_at
Participates
as an input of
as a component of
Other forms of this molecule
UBA1 [cytosol]
Inferred To
Uba1 [nucleoplasm] (Drosophila melanogaster)
uba-1 [nucleoplasm] (Caenorhabditis elegans)
UBA1 [nucleoplasm] (Bos taurus)
UBA1 [nucleoplasm] (Canis familiaris)
UBA1 [nucleoplasm] (Danio rerio)
UBA1 [nucleoplasm] (Dictyostelium discoideum)
UBA1 [nucleoplasm] (Gallus gallus)
UBA1 [nucleoplasm] (Mus musculus)
UBA1 [nucleoplasm] (Plasmodium falciparum)
UBA1 [nucleoplasm] (Rattus norvegicus)
UBA1 [nucleoplasm] (Saccharomyces cerevisiae)
UBA1 [nucleoplasm] (Schizosaccharomyces pombe)
UBA1 [nucleoplasm] (Sus scrofa)
uba1 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
HPA
ZINC - Substances
Ensembl
ZINC target
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (12)
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