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Partially folded GNB4 [cytosol]
Stable Identifier
R-HSA-8850525
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Partially folded G-protein subunit beta-4
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Homo sapiens)
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Homo sapiens)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta subunit [cytosol] (Homo sapiens)
Partially folded GNB4 [cytosol] (Homo sapiens)
PDCL binds G-protein beta and TRiC/CCT (Homo sapiens)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta subunit [cytosol] (Homo sapiens)
Partially folded GNB4 [cytosol] (Homo sapiens)
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta subunit [cytosol] (Homo sapiens)
Partially folded GNB4 [cytosol] (Homo sapiens)
PDCL releases folded G-beta from TRiC/CCT (Homo sapiens)
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta 1-4 [cytosol] (Homo sapiens)
Partially folded GNB4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HAV0 GNB4
Gene Names
GNB4
Chain
initiator methionine:, chain:2-340
Reference Genes
BioGPS Gene:59345 GNB4
COSMIC (genes):GNB4 GNB4
CTD Gene:59345 GNB4
dbSNP Gene:59345 GNB4
ENSEMBL:ENSG00000114450 GNB4
HGNC:20731 GNB4
KEGG:hsa:59345 GNB4
Monarch:59345 GNB4
NCBI Gene:59345 GNB4
OMIM:610863 GNB4
UCSC:Q9HAV0 GNB4
Reference Transcript
RefSeq:NM_021629.3 GNB4
RefSeq:XM_005247692.2 GNB4
RefSeq:XM_006713721.2 GNB4
Other Identifiers
11723102_at
11723103_x_at
11723104_at
11751252_a_at
16961806
223487_3p_x_at
223487_PM_x_at
223487_x_at
223488_PM_s_at
223488_s_at
225710_PM_at
225710_at
2706935
2706937
2706939
2706940
2706941
2706942
2706943
2706945
2706946
2706947
2706949
2706950
2706951
2706952
2706954
2706955
2706960
2706961
2706962
2706963
2706964
2706969
54807_at
59345
62744_at
8092251
A_23_P18186
A_32_P171313
A_32_P184916
GE501776
GE62852
GO:0005515
GO:0005737
GO:0005765
GO:0005829
GO:0005834
GO:0007165
GO:0007186
GO:0021762
GO:0030159
GO:0043226
GO:0044297
GO:0044877
GO:0045202
GO:0048856
GO:0060090
GO:0070062
HMNXSV003022963
HMNXSV003040417
Hs.172654.0.S2_3p_at
Hs.173030.0.A1_3p_at
ILMN_1733249
ILMN_2129545
PH_hs_0010369
PH_hs_0027647
TC03002038.hg
g12654118_3p_a_at
Participates
as a member of
Partially folded G-protein beta subunit [cytosol] (Homo sapiens)
Partially folded G-protein beta 1-4 [cytosol] (Homo sapiens)
Other forms of this molecule
GNB4 [plasma membrane]
Unfolded GNB4 [cytosol]
GNB4 [cytosol]
Inferred To
STE4 [cytosol]
(Saccharomyces cerevisiae)
git5 [cytosol]
(Schizosaccharomyces pombe)
gpb-1 [cytosol]
(Caenorhabditis elegans)
Gbeta76C [cytosol]
(Drosophila melanogaster)
Gnb4 [cytosol]
(Rattus norvegicus)
G-protein beta 4 subunit [cytosol]
(Mus musculus)
gnb4 [cytosol]
(Xenopus tropicalis)
Gbeta13F [cytosol]
(Drosophila melanogaster)
Homologues of GNB1 [cytosol]
(Drosophila melanogaster)
gpbA [cytosol]
(Dictyostelium discoideum)
GNB4 [cytosol]
(Bos taurus)
GNB4 [cytosol]
(Canis familiaris)
GNB4 [cytosol]
(Gallus gallus)
GNB4 [cytosol]
(Sus scrofa)
Cross References
RefSeq
XP_006713784.1
,
NP_067642.1
,
XP_005247749.1
ENSEMBL
ENSP00000501882
,
ENST00000676128
,
ENST00000674862
,
ENSP00000232564
,
ENSP00000502628
,
ENST00000232564
OpenTargets
ENSG00000114450
HPA
ENSG00000114450-GNB4
PRO
Q9HAV0
Pharos - Targets
Q9HAV0
GlyGen
Q9HAV0
Orphanet
GNB4
HMDB Protein
HMDBP08401
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P55212 CASP6
5
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
UniProt:P18827 SDC1
20
HS(4)-SDC1 [plasma membrane]
(R-HSA-2076693)
HS(6)-SDC1 [plasma membrane]
(R-HSA-2076652)
HS(2)-SDC1 [plasma membrane]
(R-HSA-2076666)
HS(1)-SDC1 [plasma membrane]
(R-HSA-2076672)
HS(3)-SDC1 [plasma membrane]
(R-HSA-2076691)
HS(5)-SDC1 [plasma membrane]
(R-HSA-2076626)
SDC1 [plasma membrane]
(R-HSA-174758)
XylS-SDC1 [Golgi lumen]
(R-HSA-2064146)
Gal-Xyl-SDC1 [Golgi lumen]
(R-HSA-2064148)
SDC1 [Golgi lumen]
(R-HSA-2054105)
Gal-Gal-Xyl-SDC1 [Golgi lumen]
(R-HSA-2064247)
GlcA-Gal-Gal-Xyl-SDC1 [Golgi lumen]
(R-HSA-2064082)
HS(3)-SDC1 [Golgi lumen]
(R-HSA-2076444)
HS(4)-SDC1 [Golgi lumen]
(R-HSA-2076593)
HS(2)-SDC1 [Golgi lumen]
(R-HSA-2076309)
HS(1)-SDC1 [Golgi lumen]
(R-HSA-2076321)
Heparan(4)-SDC1 [Golgi lumen]
(R-HSA-2076339)
Heparan(3)-SDC1 [Golgi lumen]
(R-HSA-2076314)
Heparan(2)-SDC1 [Golgi lumen]
(R-HSA-2076558)
Heparan(1)-SDC1 [Golgi lumen]
(R-HSA-2076349)
0.527
2
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