Reactome | GNB4 [cytosol]

Hemostasis (Sus scrofa)

- Platelet activation, signaling and aggregation (Sus scrofa)
  - Signal amplification (Sus scrofa)
    - ADP signalling through P2Y purinoceptor 1 (Sus scrofa)
      - Dissociation of the P2Y purinoceptor 1:Gq complex (Sus scrofa)
        
        ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - ADP signalling through P2Y purinoceptor 12 (Sus scrofa)
      - Activated P2Y purinoceptor 12 binds G-protein Gi (Sus scrofa)
        
        ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Dissociation of the P2Y purinoceptor 12:Gi complex (Sus scrofa)
        
        ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Gi activation by P2Y purinoceptor 12 (Sus scrofa)
        
        ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - Thromboxane signalling through TP receptor (Sus scrofa)
      - Activated TP receptor binds G-proten Gq (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Dissociation of the TP:Gq complex (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - G13 activation by TP receptor (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Gq activation by TP receptor (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
  - Thrombin signalling through proteinase activated receptors (PARs) (Sus scrofa)
    - Dissociation of the PAR:G12/13 complex (Sus scrofa)
      - G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - Dissociation of the PAR:Gq complex (Sus scrofa)
      - G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - G12/13 activation by PAR (Sus scrofa)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - Gq activation by PAR (Sus scrofa)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Thrombin-activated PAR:Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - Thrombin-activated PAR binds G-protein Gq (Sus scrofa)
      - Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Thrombin-activated PAR:Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
- Platelet homeostasis (Sus scrofa)
  - Prostacyclin signalling through prostacyclin receptor (Sus scrofa)
    - Gs activation by prostacyclin receptor (Sus scrofa)
      - Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)

Metabolism of proteins (Sus scrofa)

- Protein folding (Sus scrofa)
  - Chaperonin-mediated protein folding (Sus scrofa)
    - Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Sus scrofa)
      - ATP binds G-protein beta associated TRiC/CCT (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ATP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ATP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - G-protein alpha releases G-protein heterotrimer from PDCL (Sus scrofa)
        
        G-protein heterotrimer [plasma membrane] (Sus scrofa)
        
        G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        p-S18,S19,S20,S25-PDCL:G-protein beta 1-4:gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta 1-4:gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - PDCL binds G-protein beta and TRiC/CCT (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - PDCL promotes formation of G-beta:G-gamma heterodimers (Sus scrofa)
        
        p-S18,S19,S20,S25-PDCL:G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        p-S18,S19,S20,S25-PDCL:G-protein beta 1-4:gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta 1-4:gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - PDCL releases folded G-beta from TRiC/CCT (Sus scrofa)
        
        p-S18,S19,S20,S25-PDCL:G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        G-protein beta 1-4 subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - TRiC/CCT binds unfolded G-protein beta subunit (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)

Neuronal System (Sus scrofa)

- Potassium Channels (Sus scrofa)
  - Inwardly rectifying K+ channels (Sus scrofa)
    - G protein gated Potassium channels (Sus scrofa)
      - Activation of G protein gated Potassium channels (Sus scrofa)
        
        Activation of GIRK/Kir3 Channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Association of GABA B receptor with G protein beta-gamma subunits (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
- Transmission across Chemical Synapses (Sus scrofa)
  - Neurotransmitter receptors and postsynaptic signal transmission (Sus scrofa)
    - Activation of kainate receptors upon glutamate binding (Sus scrofa)
      - Presynaptic function of Kainate receptors (Sus scrofa)
        
        Activation of GRIK3 homomer (Sus scrofa)
        
        G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Kainate receptor-glutamate-Gprotein complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - GABA receptor activation (Sus scrofa)
      - GABA B receptor activation (Sus scrofa)
        
        Activation of GABAB receptors (Sus scrofa)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Sus scrofa)
        
        Activation of GIRK/Kir3 Channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Association of GABA B receptor with G protein beta-gamma subunits (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (12/13) signalling events (Sus scrofa)
      - Inactive G alpha (12/13) reassociates with G beta:gamma (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Sus scrofa)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Sus scrofa)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - The Ligand:GPCR:G12/13 complex dissociates (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein G12 (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Sus scrofa)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Sus scrofa)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Inactive G alpha (i) reassociates with G beta:gamma (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Opioid Signalling (Sus scrofa)
        
        G-protein activation (Sus scrofa)
        
        G-protein beta-gamma subunits rebind the alpha-GDP subunit (Sus scrofa)
        
        G protein-GDP complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        The high affinity receptor complex binds to G-protein (Sus scrofa)
        
        G protein-GDP complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Opioid:MOR:G protein-GDP complex [plasma membrane] (Sus scrofa)
        
        G protein-GDP complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        The receptor:G-protein complex binds GTP (Sus scrofa)
        
        Opioid:MOR:G protein-GTP complex [plasma membrane] (Sus scrofa)
        
        G protein-GTP [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        The receptor:G-protein complex dissociates (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Opioid:MOR:G protein-GTP complex [plasma membrane] (Sus scrofa)
        
        G protein-GTP [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        The receptor:G-protein complex releases GDP (Sus scrofa)
        
        Opioid:MOR:G protein-GDP complex [plasma membrane] (Sus scrofa)
        
        G protein-GDP complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Opsins act as GEFs for G alpha-t (Sus scrofa)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Sus scrofa)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Sus scrofa)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Opsins binds G alpha-t (Sus scrofa)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Sus scrofa)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Inactive G alpha (q) reassociates with G beta:gamma (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - G alpha (s) signalling events (Sus scrofa)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - G alpha (z) signalling events (Sus scrofa)
      - Inactive G alpha (z) reassociates with G beta:gamma (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded Gz-activating GPCR acts as a GEF for Gz (Sus scrofa)
        
        ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gz (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Sus scrofa)
        
        Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gz (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - The Ligand:GPCR:Gz complex dissociates (Sus scrofa)
        
        ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein Gz (active) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
    - G-protein beta:gamma signalling (Sus scrofa)
      - G beta:gamma signalling through BTK (Sus scrofa)
        
        BTK in PIP3:BTK:G beta-gamma complex is activated (Sus scrofa)
        
        PIP3:BTK:G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G beta-gamma complex and PIP3 recruit BTK to membrane (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        PIP3:BTK:G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        PIP3:BTK:G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - G beta:gamma signalling through CDC42 (Sus scrofa)
        
        Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex:PAK1:ARHGEF6:CDC42 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma complex:Active PAK1:ARHGEF6 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - G beta:gamma signalling through PI3Kgamma (Sus scrofa)
        
        G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Sus scrofa)
        
        G-protein beta-gamma:PI3K gamma [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - G beta:gamma signalling through PLC beta (Sus scrofa)
        
        Gbeta:gamma activation of PLC beta (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        PLC beta-mediated PIP2 hydrolysis (Sus scrofa)
        
        G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
- Signaling by WNT (Sus scrofa)
  - Beta-catenin independent WNT signaling (Sus scrofa)
    - Ca2+ pathway (Sus scrofa)
      - G-protein subunits dissociate from WNT:FZD complex (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - Gbeta:gamma activation of PLC beta (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - PLC beta-mediated PIP2 hydrolysis (Sus scrofa)
        
        G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
      - WNT:FZD complex promotes G-protein nucleotide exchange (Sus scrofa)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Sus scrofa)
        
        Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Sus scrofa)
        
        G-protein beta-gamma complex [plasma membrane] (Sus scrofa)
        
        G-protein beta subunit [cytosol] (Sus scrofa)
        
        GNB4 [cytosol] (Sus scrofa)