Reactome | GNGT1 [photoreceptor disc membrane]

GNGT1 [photoreceptor disc membrane]

Stable Identifier

R-HSA-55393

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

photoreceptor disc membrane

Synonyms

Guanine nucleotide-binding protein G(T) gamma-T1 subunit, Transducin gamma chain

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P63211 GNGT1

Gene Names

GNGT1

Chain

initiator methionine:1, chain:2-71, propeptide:72-74

Reference Genes

BioGPS Gene:2792 GNGT1

COSMIC - genes:GNGT1 GNGT1

CTD Gene:2792 GNGT1

dbSNP Gene:2792 GNGT1

ENSEMBL:ENSG00000127928 GNGT1

HGNC:4411 GNGT1

KEGG:hsa:2792 GNGT1

Monarch:2792 GNGT1

NCBI Gene:2792 GNGT1

OMIM:189970 GNGT1

UCSC:P63211 GNGT1

Reference Transcript

Other Identifiers

11733301_at

17048437

207166_PM_at

207166_at

2792

3012911

3012933

3012937

3012938

3012939

3012941

3012942

3012943

3012944

36772_at

8134252

AC002076_cds2_at

A_14_P132836

A_23_P123096

A_24_P196665

GE586795

GE59143

GO:0001750

GO:0001917

GO:0003924

GO:0005515

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007602

GO:0008104

GO:0010659

GO:0016020

GO:0016787

GO:0031681

GO:0042462

GO:0048856

GO:0071456

GO:0097381

HMNXSV003007527

ILMN_2091100

PH_hs_0027672

S62027_s_at

TC07000553.hg

g11386178_3p_at

Participates

as an input of

FNTA:FNTB transfers FARN to GNGT1 (Homo sapiens)

Other forms of this molecule

GNGT1 [plasma membrane]

S-farn-GNGT1 [photoreceptor disc membrane]

Inferred To

Gngt1 [photoreceptor disc membrane] (Bos taurus)

Gngt1 [photoreceptor disc membrane] (Mus musculus)

Gngt1 [photoreceptor disc membrane] (Rattus norvegicus)

GNGT1 [photoreceptor disc membrane] (Canis familiaris)

GNGT1 [photoreceptor disc membrane] (Sus scrofa)

gngt1 [photoreceptor disc membrane] (Danio rerio)

gngt1 [photoreceptor disc membrane] (Xenopus tropicalis)

gpc-1 [photoreceptor disc membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001316355.1, NP_068774.1

OpenTargets

ENSG00000127928

ENSEMBL

ENSP00000388777, ENSG00000127928, ENSP00000248572, ENST00000429473, ENST00000248572

HPA

ENSG00000127928-GNGT1

GeneCards

GNGT1

PRO

P63211

Pharos - Targets

P63211

PDB

7L0S, 7L0P, 7L0Q, 7L0R

HMDB Protein

HMDBP08407

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62873 GNB1	5	GNB1 [cytosol] (R-HSA-6814412) GNB1 [plasma membrane] (R-HSA-164347) Partially folded GNB1 [cytosol] (R-HSA-8850526) Unfolded GNB1 [cytosol] (R-HSA-6814200) GNB1 [photoreceptor disc membrane] (R-HSA-55373)	0.774	11
UniProt:P20789	1	Ntsr1 [plasma membrane] (R-RNO-388916)	0.75	16
UniProt:P62873-1 GNB1			0.672	7
UniProt:P20068-PRO_0000019532 NTS			0.672	6
UniProt:P63096-1 GNAI1			0.672	7
UniProt:P62879 GNB2	4	GNB2 [cytosol] (R-HSA-6814421) Partially folded GNB2 [cytosol] (R-HSA-8850536) Unfolded GNB2 [cytosol] (R-HSA-6814202) GNB2 [plasma membrane] (R-HSA-164335)	0.623	7
UniProt:Q9HAV0 GNB4	4	GNB4 [cytosol] (R-HSA-6814417) Partially folded GNB4 [cytosol] (R-HSA-8850525) Unfolded GNB4 [cytosol] (R-HSA-6814201) GNB4 [plasma membrane] (R-HSA-164326)	0.623	6
UniProt:P16520 GNB3	4	Unfolded GNB3 [cytosol] (R-HSA-6814203) Partially folded GNB3 [cytosol] (R-HSA-8850532) GNB3 [plasma membrane] (R-HSA-164355) GNB3 [cytosol] (R-HSA-6814414)	0.623	6
ChEBI:197393 (1R,2R)-2-PCCA			0.557	3
UniProt:Q8NCY6 MSD4			0.556	3
UniProt:Q8WWA6 Q8WWA6			0.556	3
UniProt:Q9H8Y8 GORASP2	2	GORASP2 [Golgi membrane] (R-HSA-2422385) p-T222,T225-GORASP2 [Golgi membrane] (R-HSA-2422965)	0.556	5
UniProt:Q92575 UBXN4			0.556	3
UniProt:G5E9M4 G5E9M4			0.556	3
UniProt:Q13371 PDCL	2	p-S18,S19,S20,S25-PDCL [cytosol] (R-HSA-6814228) PDCL [cytosol] (R-HSA-6813727)	0.499	2
UniProt:P63096 GNAI1	1	GNAI1 [plasma membrane] (R-HSA-55431)	0.499	11
UniProt:P63092-1 GNAS			0.499	9

Cite Us!