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About
What is Reactome ?
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Team
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Release Calendar
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Our Logo
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Privacy Notice
Disclaimer
Digital Preservation
Contact us
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p-Y1007-JAK2 [cytosol]
Stable Identifier
R-HSA-873799
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p(Y1007)-JAK2, p-JAK2 (Y1007), Activated JAK2
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
Dimerization of STATs downstream of KIT mutants (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of JAK2 downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Recruitment of STATs by KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Growth hormone receptor signaling (Homo sapiens)
JAK2 binds STAT1/3 (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:STAT1/STAT3 [plasma membrane] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK2 phosphorylates STAT1/STAT3 (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:STAT1/STAT3 [plasma membrane] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:p(Y701)-STAT1/p(Y705)-STAT3 [plasma membrane] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK2 phosphorylation (Homo sapiens)
Activated cytokine-like hormone receptors, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK2 phosphorylation of GHR (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK2 phosphorylation of IRS-1/2 (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PTP1B binds the GH receptor complex (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PTP1B dephosphorylates GHR (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PTP1B dephosphorylates JAK2 (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SHP1 (PTPN6) binds JAK2 in the receptor complex (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SHP1 (PTPN6) dephosphorylates JAK2 (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SOCS binding to GHR (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:CIS/SOCS1-3 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SOCS binding to JAK2 (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SOCS [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
STAT5 association with GHR (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:STAT5 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
STAT5 tyrosine phosphorylation (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:STAT5 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-STAT5A/B dissociates from the Growth Hormone receptor (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Binding of STAT1 to p-IFNGR1 (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
STAT1 bound to p-IFNGR1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG signaling activates MAPKs (Homo sapiens)
Activated JAK1 binds RAF1 (Homo sapiens)
IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK1-activated RAF1 phosphorylates MAPKs (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK1-mediated phosphorylation of RAF1 (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK2-activated MAPKs phosphorylate YBX1 (Homo sapiens)
IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of IFNGR1 by JAK kinases (Homo sapiens)
IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of JAK2 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of STAT1 at Ser727 (Homo sapiens)
p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of STAT1 by JAK kinases (Homo sapiens)
STAT1 bound to p-IFNGR1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Regulation of IFNG signaling (Homo sapiens)
Dephosphorylation of JAKs by PTPs (Homo sapiens)
IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SOCS-1 and SOCS-3 binds to p-JAK2 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Release of STAT1 dimer from active receptor unit (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Homo sapiens)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Transphosphorylation of JAK1 (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Homo sapiens)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IFNGR complex with p-JAK [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
JAK2 phosphorylation (Homo sapiens)
Activated cytokine-like hormone receptors, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor- p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR binds SHP2 (PTPN11) (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR binds STAT5 (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2:STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR-bound STAT5 is phosphorylated (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2:STAT5 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SHP2 is phosphorylated (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:SHP2 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-SHP2 [plasma membrane] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylation of PRLR (Homo sapiens)
PRLR ligands:Activated PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 dimer [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Activation of STAT5a/b by JAK2 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK2 is phosphorylated, activated (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
STAT5 is recruited by JAK2 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine kinases phosphorylate the receptor (Homo sapiens)
Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-STAT5 dissociates from the receptor complex (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT6 bind IL13:IL13R type II (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT6 phosphorylation (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2,p-Y-TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-Y-STATs dissociate (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Homo sapiens)
IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Interleukin-6 family signaling (Homo sapiens)
Interleukin-6 signaling (Homo sapiens)
IL6ST is tyrosine phosphorylated (Homo sapiens)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
JAK activation (Homo sapiens)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PTPN11 binds CBL (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11:CBL [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PTPN11 binds p-Y759-IL6ST (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
PTPN11 is phosphorylated (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylated STATs are released (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
SOCS3 binds IL6ST (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Serine phosphorylation of STATs (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF-independent MAPK1/3 activation (Homo sapiens)
MAPK1 (ERK2) activation (Homo sapiens)
MAP2K2 binds MAPK1 (Homo sapiens)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
MAPK3 (ERK1) activation (Homo sapiens)
MAP2K1 binds MAPK3 (Homo sapiens)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
IL6:sIL6R:Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated IL6ST:Activated JAKs [plasma membrane] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
Dimerization of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of JAK2 (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Phosphorylation of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
Recruitment of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
p-Y1007-JAK2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60674 JAK2
Gene Names
JAK2
Chain
chain:1-1132
Reference Genes
BioGPS Gene:3717 JAK2
COSMIC (genes):JAK2 JAK2
CTD Gene:3717 JAK2
dbSNP Gene:3717 JAK2
ENSEMBL:ENSG00000096968 JAK2
HGNC:6192 JAK2
KEGG:hsa:3717 JAK2
Monarch:3717 JAK2
NCBI Gene:3717 JAK2
OMIM:147796 JAK2
UCSC:O60674 JAK2
Reference Transcript
RefSeq:NM_001322196.1 JAK2
RefSeq:NM_001322194.1 JAK2
RefSeq:NM_001322204.1 JAK2
RefSeq:NM_001322195.1 JAK2
RefSeq:NM_004972.3 JAK2
Other Identifiers
11733372_a_at
11733373_at
11756857_a_at
17083319
205841_PM_at
205841_at
205842_PM_s_at
205842_s_at
3160892
3160894
3160896
3160897
3160898
3160899
3160904
3160905
3160906
3160907
3160931
3160932
3160933
3160935
3160936
3160937
3160941
3160944
3160946
3160947
3160949
3160950
3160951
3160953
3160954
3160956
3160957
3160958
3160960
3160962
3160963
3161009
3161012
3161013
3161014
3161015
3161016
3161017
3161019
3161020
3161022
3717
37468_at
78910_i_at
78912_r_at
8154178
A_14_P105543
A_14_P127099
A_14_P136058
A_23_P123608
A_33_P3878772
GE79112
GO:0000791
GO:0001774
GO:0002250
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005131
GO:0005143
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006366
GO:0006468
GO:0006915
GO:0006919
GO:0006955
GO:0006979
GO:0007165
GO:0007167
GO:0007186
GO:0007204
GO:0007259
GO:0007260
GO:0007498
GO:0008284
GO:0008285
GO:0008631
GO:0009755
GO:0009898
GO:0010572
GO:0010667
GO:0010811
GO:0012501
GO:0012505
GO:0014070
GO:0014075
GO:0016020
GO:0016740
GO:0018108
GO:0019221
GO:0019897
GO:0019901
GO:0020037
GO:0022408
GO:0030041
GO:0030099
GO:0030154
GO:0030155
GO:0030218
GO:0030335
GO:0030526
GO:0031103
GO:0031234
GO:0031702
GO:0031904
GO:0031959
GO:0032024
GO:0032496
GO:0032729
GO:0032731
GO:0032740
GO:0032760
GO:0032819
GO:0033130
GO:0033194
GO:0033209
GO:0034050
GO:0034612
GO:0035166
GO:0035401
GO:0035556
GO:0035722
GO:0036016
GO:0038043
GO:0038065
GO:0038155
GO:0038156
GO:0038157
GO:0038162
GO:0042022
GO:0042102
GO:0042169
GO:0042307
GO:0042393
GO:0042531
GO:0042802
GO:0042976
GO:0042981
GO:0043065
GO:0043066
GO:0043226
GO:0043392
GO:0043410
GO:0043524
GO:0043548
GO:0043560
GO:0043687
GO:0045087
GO:0045121
GO:0045348
GO:0045428
GO:0045429
GO:0045597
GO:0045944
GO:0046425
GO:0046427
GO:0046677
GO:0046777
GO:0046872
GO:0048008
GO:0048856
GO:0050727
GO:0050804
GO:0050867
GO:0051142
GO:0051239
GO:0051428
GO:0051770
GO:0051897
GO:0060333
GO:0060391
GO:0060396
GO:0060397
GO:0060399
GO:0061180
GO:0065003
GO:0070102
GO:0070665
GO:0070671
GO:0070757
GO:0071222
GO:0071549
GO:0072536
GO:0097191
GO:0097296
GO:0098542
GO:0098586
GO:0098794
GO:0098978
GO:0120162
GO:0140096
GO:1901731
GO:1902728
GO:1904037
GO:1904707
GO:1905539
GO:2000273
GO:2000318
GO:2001235
HMNXSV003006385
ILMN_1683178
PH_hs_0025325
TC09000035.hg
g13325062_3p_at
g3236321_3p_a_at
Participates
as a component of
p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
Tyrosine phosphorylated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
p(Y593)-IL3RB:Activated JAK2 [plasma membrane] (Homo sapiens)
Activated Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
Activated PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p(Y611)-PRLR:p(Y1007)-JAK2 [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
IFNGR2:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
as a member of
p-Y1007-JAK2,p-Y-TYK2 [cytosol] (Homo sapiens)
Activated JAK1, JAK2, TYK2 [cytosol] (Homo sapiens)
Other forms of this molecule
JAK2 [cytosol]
p-12Y-JAK2 [cytosol]
JAK2 [endosome lumen]
JAK2 V617F [nucleoplasm]
p-Y813-JAK2 [cytosol]
p-JAK2 [cytosol]
p-Y1007,Y1008-JAK2 [cytosol]
Inferred To
p-Y1007-Jak2 [cytosol]
(Rattus norvegicus)
phospho-p-Y1007-JAK2 [cytosol]
(Bos taurus)
phospho-p-Y1007-JAK2 [cytosol]
(Canis familiaris)
phospho-p-Y1007-JAK2 [cytosol]
(Danio rerio)
phospho-p-Y1007-JAK2 [cytosol]
(Drosophila melanogaster)
phospho-p-Y1007-JAK2 [cytosol]
(Gallus gallus)
phospho-p-Y1007-JAK2 [cytosol]
(Mus musculus)
phospho-p-Y1007-JAK2 [cytosol]
(Sus scrofa)
phospho-p-Y1007-JAK2 [cytosol]
(Xenopus tropicalis)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1007
Coordinate
1007
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_004963.1
,
NP_001309133.1
,
NP_001309125.1
,
NP_001309124.1
,
NP_001309123.1
ZINC - World Drugs
JAK2_HUMAN
Guide to Pharmacology - Targets
2048
OpenTargets
ENSG00000096968
ENSEMBL
ENSP00000371067
,
ENST00000381652
ZINC - FDA approved
JAK2_HUMAN
ZINC - Substances
JAK2_HUMAN
ZINC - Biogenic
JAK2_HUMAN
ZINC target
O60674
PRO
O60674
GlyGen
O60674
PDB
7F7W
,
6OCC
,
6BBV
,
4ZIM
,
4GMY
,
8BA3
,
3KCK
,
6VNE
,
6M9H
,
5TQ5
,
6TPD
,
6AAJ
,
5USZ
,
4AQC
,
8CZ9
,
7LL4
,
5UT3
,
8BA2
,
5L3A
,
8BPV
,
7Q7K
,
7Q7W
,
6WTP
,
6VN8
,
7Q7I
,
5TQ8
,
6VNK
,
5WIN
,
3IOK
,
7REE
,
5HEZ
,
6XJK
,
4FVR
,
5CF4
,
8BAK
,
8B8U
,
4YTF
,
8B9H
,
5AEP
,
2W1I
,
3LPB
,
7T1T
,
4BBE
,
4F08
,
5CF8
,
6VNL
,
7JYO
,
6VSN
,
2XA4
,
6VS3
,
4JIA
,
4IVA
,
5USY
,
8BX9
,
4E6D
,
7LL5
,
5WIL
,
8BXH
,
7Q7L
,
8BPW
,
6BRW
,
6VNJ
,
8F88
,
6E2Q
,
6WTN
,
3ZMM
,
8B8N
,
4D1S
,
4YTI
,
4C61
,
8BAB
,
6OAV
,
4GFM
,
3IO7
,
3RVG
,
3UGC
,
3JY9
,
8EYA
,
8EX2
,
4E6Q
,
5WEV
,
8G6Z
,
5UT6
,
3Q32
,
3FUP
,
5UT5
,
6VNM
,
8BA4
,
5TQ4
,
7RN6
,
8C08
,
5TQ3
,
8C09
,
8BX6
,
4D0W
,
3E62
,
5UT2
,
6VNG
,
3KRR
,
4Z32
,
4P7E
,
3E64
,
5UT0
,
6VNI
,
8G8O
,
4F09
,
8G8X
,
5WIM
,
6VNC
,
7TEU
,
5TQ7
,
6OBB
,
4FVP
,
3TJC
,
4YTC
,
4HGE
,
5CF5
,
6D2I
,
5CF6
,
8EX0
,
5I4N
,
5UT4
,
4BBF
,
8EXK
,
6BS0
,
7JYQ
,
6G3C
,
2B7A
,
6OBL
,
4E4M
,
4JI9
,
8C0A
,
6BSS
,
3E63
,
6WTQ
,
6VNF
,
4D0X
,
5WIJ
,
6E2P
,
6WTO
,
6VNH
,
8BXC
,
6DRW
,
5WIK
,
5UT1
,
6X8E
,
7UYW
,
6VNB
,
5TQ6
,
3TJD
,
4YTH
,
6VGL
,
8BM2
,
4C62
,
4FVQ
,
8B99
,
8EX1
,
8EYB
,
6OBF
,
8B9E
,
7T0P
ZINC - Investigational
JAK2_HUMAN
HPA
ENSG00000096968-JAK2
Pharos - Targets
O60674
Orphanet
JAK2
ZINC - Predictions - Purchasable
JAK2_HUMAN
HMDB Protein
HMDBP01194
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18031 PTPN1
2
PTPN1 [endosome membrane]
(R-HSA-9815895)
PTPN1 [cytosol]
(R-HSA-210625)
0.819
5
UniProt:O60674 JAK2
8
JAK2 [cytosol]
(R-HSA-210620)
p-Y1007-JAK2 [cytosol]
(R-HSA-873799)
p-12Y-JAK2 [cytosol]
(R-HSA-2586516)
JAK2 [endosome lumen]
(R-HSA-2002372)
JAK2 V617F [nucleoplasm]
(R-HSA-5211269)
p-Y813-JAK2 [cytosol]
(R-HSA-997248)
p-JAK2 [cytosol]
(R-HSA-210621)
p-Y1007,Y1008-JAK2 [cytosol]
(R-HSA-9005327)
0.623
7
UniProt:P32927 CSF2RB
6
p-Y593,Y628-CSF2RB [plasma membrane]
(R-HSA-912312)
CSF2RB [plasma membrane]
(R-HSA-879960)
p-S585-CSF2RB [plasma membrane]
(R-HSA-914170)
p-Y593-CSF2RB [plasma membrane]
(R-HSA-914092)
CSF2RB R211Efs*54 [plasma membrane]
(R-HSA-5688863)
CSF2RB S271L [plasma membrane]
(R-HSA-5688879)
0.564
4
UniProt:Q9NZI7 UBIP1
0.527
2
UniProt:Q9NRF2 SH2B1
1
SH2B1 [cytosol]
(R-HSA-997253)
0.527
2
UniProt:Q9JHI9
1
SLC40A1 [plasma membrane]
(R-MMU-442390)
0.524
3
UniProt:P40238 MPL
1
MPL [plasma membrane]
(R-HSA-443938)
0.518
6
UniProt:Q01344 IL5RA
1
IL5RA [plasma membrane]
(R-HSA-450072)
0.499
2
UniProt:P23458 JAK1
6
p-Y-JAK1 [cytosol]
(R-HSA-451921)
JAK1 [cytosol]
(R-HSA-451898)
p-Y1034-JAK1 [cytosol]
(R-HSA-1112543)
p-JAK1 [cytosol]
(R-HSA-8950711)
JAK1 [endosome]
(R-HSA-8983168)
p-Y1034,Y1035-JAK1 [cytosol]
(R-HSA-9005335)
0.463
4
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