JAK2 [cytosol]

Stable Identifier
R-HSA-210620
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosine-protein kinase JAK2
Icon
JAK2 [cytosol] icon
JAK2 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O60674 JAK2
Gene Names
JAK2
Chain
chain:1-1132
Reference Genes
BioGPS Gene:3717 JAK2
COSMIC (genes):JAK2 JAK2
CTD Gene:3717 JAK2
dbSNP Gene:3717 JAK2
ENSEMBL:ENSG00000096968 JAK2
HGNC:6192 JAK2
KEGG:hsa:3717 JAK2
Monarch:3717 JAK2
NCBI Gene:3717 JAK2
OMIM:147796 JAK2
UCSC:O60674 JAK2
Reference Transcript
Other Identifiers
11733372_a_at
11733373_at
11756857_a_at
17083319
205841_PM_at
205841_at
205842_PM_s_at
205842_s_at
3160892
3160894
3160896
3160897
3160898
3160899
3160904
3160905
3160906
3160907
3160931
3160932
3160933
3160935
3160936
3160937
3160941
3160944
3160946
3160947
3160949
3160950
3160951
3160953
3160954
3160956
3160957
3160958
3160960
3160962
3160963
3161009
3161012
3161013
3161014
3161015
3161016
3161017
3161019
3161020
3161022
3717
37468_at
78910_i_at
78912_r_at
8154178
A_14_P105543
A_14_P127099
A_14_P136058
A_23_P123608
A_33_P3878772
GE79112
GO:0000791
GO:0001774
GO:0002250
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005131
GO:0005143
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006366
GO:0006468
GO:0006915
GO:0006919
GO:0006955
GO:0006979
GO:0007165
GO:0007167
GO:0007186
GO:0007204
GO:0007259
GO:0007260
GO:0007498
GO:0008284
GO:0008285
GO:0008631
GO:0009755
GO:0009898
GO:0010572
GO:0010667
GO:0010811
GO:0012501
GO:0012505
GO:0014070
GO:0014075
GO:0016020
GO:0016740
GO:0018108
GO:0019221
GO:0019897
GO:0019901
GO:0020037
GO:0022408
GO:0030041
GO:0030099
GO:0030154
GO:0030155
GO:0030218
GO:0030335
GO:0030526
GO:0031103
GO:0031234
GO:0031702
GO:0031904
GO:0031959
GO:0032024
GO:0032496
GO:0032729
GO:0032731
GO:0032740
GO:0032760
GO:0032819
GO:0033130
GO:0033194
GO:0033209
GO:0034050
GO:0034612
GO:0035166
GO:0035401
GO:0035556
GO:0035722
GO:0036016
GO:0038043
GO:0038065
GO:0038155
GO:0038156
GO:0038157
GO:0038162
GO:0042022
GO:0042102
GO:0042169
GO:0042307
GO:0042393
GO:0042531
GO:0042802
GO:0042976
GO:0042981
GO:0043065
GO:0043066
GO:0043226
GO:0043392
GO:0043410
GO:0043524
GO:0043548
GO:0043560
GO:0043687
GO:0045087
GO:0045121
GO:0045348
GO:0045428
GO:0045429
GO:0045597
GO:0045944
GO:0046425
GO:0046427
GO:0046677
GO:0046777
GO:0046872
GO:0048008
GO:0048856
GO:0050727
GO:0050804
GO:0050867
GO:0051142
GO:0051239
GO:0051428
GO:0051770
GO:0051897
GO:0060333
GO:0060391
GO:0060396
GO:0060397
GO:0060399
GO:0061180
GO:0065003
GO:0070102
GO:0070665
GO:0070671
GO:0070757
GO:0071222
GO:0071549
GO:0072536
GO:0097191
GO:0097296
GO:0098542
GO:0098586
GO:0098794
GO:0098978
GO:0120162
GO:0140096
GO:1901731
GO:1902728
GO:1904037
GO:1904707
GO:1905539
GO:2000273
GO:2000318
GO:2001235
HMNXSV003006385
ILMN_1683178
PH_hs_0025325
TC09000035.hg
g13325062_3p_at
g3236321_3p_a_at
Participates
as a component of
as an input of
as a member of
as a candidate of
Other forms of this molecule
p-Y1007-JAK2 [cytosol]
p-12Y-JAK2 [cytosol]
JAK2 [endosome lumen]
JAK2 V617F [nucleoplasm]
p-Y813-JAK2 [cytosol]
p-JAK2 [cytosol]
p-Y1007,Y1008-JAK2 [cytosol]
Inferred To
JAK2 [cytosol] (Bos taurus)
JAK2 [cytosol] (Canis familiaris)
JAK2 [cytosol] (Danio rerio)
JAK2 [cytosol] (Drosophila melanogaster)
JAK2 [cytosol] (Gallus gallus)
JAK2 [cytosol] (Mus musculus)
JAK2 [cytosol] (Sus scrofa)
JAK2 [cytosol] (Xenopus tropicalis)
Jak2 [cytosol] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
3UGC, 6WTO, 8BX6, 5UT1, 4D1S, 8BM2, 4FVQ, 8BPV, 5TQ6, 8BA2, 6VN8, 4HGE, 5L3A, 8B8N, 4YTI, 3IO7, 8BAB, 3JY9, 8EYB, 6WTQ, 8EX2, 8C0A, 4BBF, 5UT4, 8F88, 3ZMM, 3TJD, 8EXK, 6VNJ, 8BXC, 5TQ5, 5CF8, 2B7A, 6VNL, 2XA4, 4JI9, 7JYQ, 6BSS, 5I4N, 3E62, 5CF6, 3KRR, 6WTP, 3E64, 5TQ8, 8BPW, 7Q7K, 4F08, 7Q7I, 6OBB, 5WIL, 4C61, 4GFM, 4Z32, 4FVR, 6D2I, 4YTC, 4D0W, 5CF5, 7LL4, 5UT3, 8EX0, 6BBV, 5WEV, 6TPD, 6M9H, 4ZIM, 4GMY, 5WIM, 6E2Q, 7TEU, 6VNC, 7T1T, 6VSN, 6VNM, 6AAJ, 7F7W, 5USZ, 8BA4, 7RN6, 4IVA, 4AQC, 4D0X, 8B9E, 7T0P, 7LL5, 8CZ9, 6VNG, 6BRW, 6WTN, 6VNI, 5TQ4, 8G8O, 7Q7W, 7Q7L, 4P7E, 4YTH, 6OAV, 8B99, 8EYA, 6OBF, 4E6D, 8EX1, 4YTF, 3E63, 6VS3, 4BBE, 8G8X, 6VNB, 7UYW, 7SZW, 5TQ3, 6OBL, 5USY, 4JIA, 7JYO, 4E4M, 2W1I, 5AEP, 3LPB, 8B9H, 5UT0, 6VNF, 8BX9, 3IOK, 5TQ7, 4FVP, 4F09, 6VNH, 6DRW, 6BS0, 8BXH, 6VGL, 4C62, 5WIK, 6XJK, 7REE, 6E2P, 5HEZ, 3RVG, 5WIJ, 5CF4, 8BAK, 8B8U, 5UT2, 8C09, 3FUP, 5UT5, 6OCC, 8G6Z, 3KCK, 5WIN, 3TJC, 6VNK, 6X8E, 8BA3, 6G3C, 6VNE, 4E6Q, 8C08, 3Q32, 5UT6
ZINC - Investigational
IntEnz
GeneCards
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (9)
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