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RHOBTB3 [trans-Golgi network membrane]
Stable Identifier
R-HSA-6813908
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Rho-related BTB domain-containing protein 3
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
RHOBTB3 ATPase cycle (Homo sapiens)
RHOBTB3 binds ATP (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 binds interacting proteins at trans-Golgi network (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ATP:RHOBTB3 interacting proteins [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 hydrolyzes ATP (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ADP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Homo sapiens)
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP [transport vesicle] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ADP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Homo sapiens)
RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP [transport vesicle] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94955 RHOBTB3
Gene Names
RHOBTB3, KIAA0878
Chain
chain:1-611
Reference Genes
BioGPS Gene:22836 RHOBTB3
COSMIC (genes):RHOBTB3 RHOBTB3
CTD Gene:22836 RHOBTB3
dbSNP Gene:22836 RHOBTB3
ENSEMBL:ENSG00000164292 RHOBTB3
ENSEMBL_homo_sapiens_GENE:ENSG00000164292.13 RHOBTB3
HGNC:18757 RHOBTB3
KEGG Gene (Homo sapiens):22836 RHOBTB3
Monarch:22836 RHOBTB3
NCBI Gene:22836 RHOBTB3
OMIM:607353 RHOBTB3
UCSC:O94955 RHOBTB3
Reference Transcript
RefSeq:NM_014899.3 RHOBTB3
Other Identifiers
11716455_at
11716456_at
11716457_x_at
11758664_s_at
16987395
202975_PM_s_at
202975_s_at
202976_3p_s_at
202976_PM_s_at
202976_s_at
216048_PM_s_at
216048_s_at
225202_PM_at
225202_at
22836
2820928
2820929
2820931
2820934
2820939
2820940
2820942
2820947
2820948
2820953
2820954
2820976
2820980
2820988
2820992
2820993
2820994
32215_i_at
32216_r_at
48793_at
8106986
A_14_P127266
A_14_P127410
A_23_P92710
A_33_P3288189
GE62933
GO:0000166
GO:0003824
GO:0003924
GO:0005515
GO:0005524
GO:0005525
GO:0005576
GO:0005615
GO:0005737
GO:0005794
GO:0005829
GO:0008584
GO:0016192
GO:0016787
GO:0016887
GO:0022414
GO:0030162
GO:0030163
GO:0031267
GO:0031625
GO:0032588
GO:0042147
GO:0043161
GO:0043226
GO:0048856
GO:0070062
GO:0140657
HMNXSV003046635
Hs.10432.0.A1_3p_at
Hs.188006.0.S1_3p_s_at
ILMN_1744949
PH_hs_0022089
TC05000461.hg
g7662355_3p_a_at
Participates
as a component of
RHOBTB3:ADP [trans-Golgi network membrane] (Homo sapiens)
RHOBTB3:ATP [trans-Golgi network membrane] (Homo sapiens)
as an input of
RHOBTB3 binds ATP (Homo sapiens)
Inferred To
mel-26 [trans-Golgi network membrane]
(Caenorhabditis elegans)
Homologues of RHOBTB3 [trans-Golgi network membrane]
(Caenorhabditis elegans)
Homologues of RHOBTB3 [trans-Golgi network membrane]
(Dictyostelium discoideum)
Rhobtb3 [trans-Golgi network membrane]
(Mus musculus)
Rhobtb3 [trans-Golgi network membrane]
(Rattus norvegicus)
Ghost homologue of RHOBTB3 [trans-Golgi network membrane]
(Danio rerio)
Ghost homologue of RHOBTB3 [trans-Golgi network membrane]
(Sus scrofa)
Ghost homologue of RHOBTB3 [trans-Golgi network membrane]
(Xenopus tropicalis)
bath-41 [trans-Golgi network membrane]
(Caenorhabditis elegans)
bath-42 [trans-Golgi network membrane]
(Caenorhabditis elegans)
rdx [trans-Golgi network membrane]
(Drosophila melanogaster)
spop-1 [trans-Golgi network membrane]
(Caenorhabditis elegans)
bath-44 [trans-Golgi network membrane]
(Caenorhabditis elegans)
bath-40 [trans-Golgi network membrane]
(Caenorhabditis elegans)
RHOBTB3 [trans-Golgi network membrane]
(Bos taurus)
RHOBTB3 [trans-Golgi network membrane]
(Canis familiaris)
RHOBTB3 [trans-Golgi network membrane]
(Dictyostelium discoideum)
RHOBTB3 [trans-Golgi network membrane]
(Gallus gallus)
Cross References
RefSeq
NP_055714.3
OpenTargets
ENSG00000164292
GeneCards
O94955
HPA
ENSG00000164292-RHOBTB3
Ensembl
ENST00000379982
,
ENSG00000164292
,
ENSP00000369318
PRO
O94955
Pharos - Targets
O94955
Interactors (23)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14503 BHLHE40
1
BHLHE40 [nucleoplasm]
(R-HSA-879741)
0.781
7
UniProt:Q5T124 UBXN11
1
UBXN11 [cytosol]
(R-HSA-9696514)
0.666
4
UniProt:Q93062 RBPMS
0.666
4
UniProt:Q13618 CUL3
3
G76-NEDD8-K712-CUL3 [cytosol]
(R-HSA-8952516)
CUL3 [nucleoplasm]
(R-HSA-5635033)
CUL3 [cytosol]
(R-HSA-975979)
0.643
4
UniProt:Q96JM7-2 L3MBTL3
0.556
3
UniProt:Q9UPG8 PLAL2
0.556
3
UniProt:Q5JST6 EFHC2
0.556
3
UniProt:Q70EL1-9 USP54
0.556
3
UniProt:Q96SF7 TBX15
0.556
3
UniProt:Q8IYA8 IHO1
0.556
3
UniProt:Q8WXH2 JPH3
0.556
3
UniProt:Q9UGI0 ZRANB1
1
ZRANB1 [cytosol]
(R-HSA-6781939)
0.556
3
UniProt:P24394 IL4R
2
IL4R [plasma membrane]
(R-HSA-449670)
p-Y-IL4R [plasma membrane]
(R-HSA-6786087)
0.527
2
UniProt:P84085 ARF5
1
ARF5 [cytosol]
(R-HSA-6807737)
0.527
2
UniProt:Q9UHG3 PCYOX
0.527
2
UniProt:O14498 ISLR
2
ISLR [extracellular region]
(R-HSA-8848919)
ISLR [platelet alpha granule lumen]
(R-HSA-8848912)
0.527
2
UniProt:Q01151 CD83
0.527
3
UniProt:P43631 KIR2DS2
1
KIR2DS2 [plasma membrane]
(R-HSA-199534)
0.527
2
UniProt:P24408
5
RAB9A [transport vesicle]
(R-CFA-6814618)
RAB9A [trans-Golgi network membrane]
(R-CFA-6814616)
GGC-RAB9A [trans-Golgi network membrane]
(R-CFA-8876087)
GGC-RAB9A [cytosol]
(R-CFA-8874069)
RAB9A [cytosol]
(R-CFA-6813904)
0.527
5
UniProt:Q96KB5 TOPK
0.527
2
UniProt:Q8TDQ0 HAVCR2
1
HAVCR2 [plasma membrane]
(R-HSA-5340408)
0.527
2
UniProt:P53611 RABGGTB
2
RABGGTB [plasma membrane]
(R-HSA-6801098)
RABGGTB [cytosol]
(R-HSA-8870419)
0.527
2
UniProt:P27930 IL1R2
1
IL1R2 [plasma membrane]
(R-HSA-197598)
0.527
2
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