Reactome | ISLR [extracellular region]

ISLR [extracellular region]

Stable Identifier

R-HSA-8848919

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Immunoglobulin superfamily containing leucine-rich repeat protein, ISLR_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O14498 ISLR

Gene Names

ISLR, UNQ189/PRO215

Chain

signal peptide:1-18, chain:19-428

Reference Genes

BioGPS Gene:3671 ISLR

COSMIC (genes):ISLR ISLR

CTD Gene:3671 ISLR

dbSNP Gene:3671 ISLR

ENSEMBL:ENSG00000129009 ISLR

HGNC:6133 ISLR

KEGG:hsa:3671 ISLR

Monarch:3671 ISLR

NCBI Gene:3671 ISLR

OMIM:602059 ISLR

UCSC:O14498 ISLR

Reference Transcript

Other Identifiers

11716549_s_at

11747852_s_at

16802960

207191_PM_s_at

207191_s_at

3601512

3601513

3601514

3601515

3671

38636_at

7984813

A_14_P110199

A_23_P3312

GE53667

GO:0005515

GO:0005576

GO:0007155

GO:0031093

GO:0043226

GO:0070062

HMNXSV003037219

ILMN_1673609

ILMN_1711009

ILMN_1747593

PH_hs_0029061

TC15000678.hg

g5031808_3p_a_at

Participates

as a member of

Platelet alpha granule contents [extracellular region] (Homo sapiens)

Other forms of this molecule

ISLR [platelet alpha granule lumen]

Inferred To

kek3 [extracellular region] (Drosophila melanogaster)

kek2 [extracellular region] (Drosophila melanogaster)

haf [extracellular region] (Drosophila melanogaster)

kek6 [extracellular region] (Drosophila melanogaster)

ISLR [extracellular region] (Bos taurus)

ISLR [extracellular region] (Canis familiaris)

ISLR [extracellular region] (Danio rerio)

ISLR [extracellular region] (Gallus gallus)

ISLR [extracellular region] (Sus scrofa)

ISLR [extracellular region] (Xenopus tropicalis)

iglr-1 [extracellular region] (Caenorhabditis elegans)

CT23878 [extracellular region] (Drosophila melanogaster)

Dmel\CG18480 [extracellular region] (Drosophila melanogaster)

kek1 [extracellular region] (Drosophila melanogaster)

kek4 [extracellular region] (Drosophila melanogaster)

Islr [extracellular region] (Mus musculus)

Islr [extracellular region] (Rattus norvegicus)

lron-6 [extracellular region] (Caenorhabditis elegans)

Lapsyn [extracellular region] (Drosophila melanogaster)

rdo [extracellular region] (Drosophila melanogaster)

Lrt [extracellular region] (Drosophila melanogaster)

CT35580 [extracellular region] (Drosophila melanogaster)

Homologues of ISLR [extracellular region] (Caenorhabditis elegans)

Homologues of ISLR [extracellular region] (Drosophila melanogaster)

Homologues of ISLR [extracellular region] (Gallus gallus)

Cross References

ENSEMBL

ENSG00000288508, ENSP00000500029, ENST00000672683, ENSG00000129009, ENST00000249842, ENSP00000378550, ENSP00000499984, ENST00000395118, ENSP00000249842, ENST00000671810

OpenTargets

ENSG00000129009

GeneCards

ISLR

HPA

ENSG00000129009-ISLR

PRO

O14498

Pharos - Targets

O14498

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.527	3
UniProt:P12236 SLC25A6	2	SLC25A6 [mitochondrial inner membrane] (R-HSA-49745) SLC25A6 [mitochondrial intermembrane space] (R-HSA-1955374)	0.527	3
UniProt:O43542 XRCC3	1	XRCC3 [nucleoplasm] (R-HSA-5685303)	0.527	2
UniProt:Q9BT09 CNPY3	1	CNPY3 [endoplasmic reticulum lumen] (R-HSA-1678932)	0.527	3
UniProt:P12235 SLC25A4	3	SLC25A4 [mitochondrial intermembrane space] (R-HSA-1267984) SLC25A4 [cytosol] (R-HSA-1267975) AAC1 [mitochondrial inner membrane] (R-HSA-49741)	0.527	3
UniProt:O94955 RHOBTB3	1	RHOBTB3 [trans-Golgi network membrane] (R-HSA-6813908)	0.527	2
UniProt:Q99741 CDC6	4	CDC6 [nucleoplasm] (R-HSA-68542) p-CDC6 [nucleoplasm] (R-HSA-5661317) p-CDC6 [cytosol] (R-HSA-68583) CDC6 [cytosol] (R-HSA-113566)	0.527	2
UniProt:O43772 SLC25A20	1	SLC25A20 [mitochondrial inner membrane] (R-HSA-200557)	0.527	2

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