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RHOBTB3 binds ATP
Stable Identifier
R-HSA-9706393
Type
Reaction [binding]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
RHOBTB3 ATPase cycle (Homo sapiens)
RHOBTB3 binds ATP (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The GTPase domain of RHOBTB3 is considerably divergent and binds ATP instead of GTP by virtue of some critical amino acid replacements in the G4 and G5 motifs (Espinosa et al. 2009).
Literature References
PubMed ID
Title
Journal
Year
19490898
RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport
Espinosa, EJ
,
Calero, M
,
Sridevi, K
,
Pfeffer, SR
Cell
2009
Participants
Input
ATP [cytosol]
RHOBTB3 [trans-Golgi network membrane]
(Homo sapiens)
Output
RHOBTB3:ATP [trans-Golgi network membrane]
(Homo sapiens)
Participates
as an event of
RHOBTB3 ATPase cycle (Homo sapiens)
Orthologous Events
RHOBTB3 binds ATP (Bos taurus)
RHOBTB3 binds ATP (Caenorhabditis elegans)
RHOBTB3 binds ATP (Canis familiaris)
RHOBTB3 binds ATP (Dictyostelium discoideum)
RHOBTB3 binds ATP (Drosophila melanogaster)
RHOBTB3 binds ATP (Gallus gallus)
RHOBTB3 binds ATP (Mus musculus)
RHOBTB3 binds ATP (Rattus norvegicus)
Authored
Rivero Crespo, F (2020-10-13)
Reviewed
Fort, P (2021-02-05)
Created
Orlic-Milacic, M (2020-11-04)
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