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RAB6A [trans-Golgi network membrane]
Stable Identifier
R-HSA-6810981
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Ras-related protein Rab-6A, Rab-6
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
Fusion of early-endosome derived vesicles at the TGN (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6A [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6A [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6A [trans-Golgi network membrane] (Homo sapiens)
RIC1:RGP1 recruits RAB6:GDP to the TGN (Homo sapiens)
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GDP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6A [trans-Golgi network membrane] (Homo sapiens)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Homo sapiens)
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GDP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6A [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6A [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20340 RAB6A
Gene Names
RAB6A, RAB6
Chain
initiator methionine:, chain:2-208
Reference Genes
COSMIC (genes):RAB6A RAB6A
dbSNP Gene:5870 RAB6A
ENSEMBL:ENSG00000175582 RAB6A
Participates
as a member of
RAB6 [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
RAB6A [endoplasmic reticulum membrane]
GGC-RAB6A [trans-Golgi network membrane]
GGC-RAB6A [cytosol]
RAB6A [cytosol]
RAB6A [plasma membrane]
RAB6A [secretory granule membrane]
RAB6A [Golgi membrane]
Inferred To
RAB6A [trans-Golgi network membrane]
(Bos taurus)
RAB6A [trans-Golgi network membrane]
(Caenorhabditis elegans)
RAB6A [trans-Golgi network membrane]
(Dictyostelium discoideum)
RAB6A [trans-Golgi network membrane]
(Drosophila melanogaster)
RAB6A [trans-Golgi network membrane]
(Gallus gallus)
RAB6A [trans-Golgi network membrane]
(Mus musculus)
RAB6A [trans-Golgi network membrane]
(Rattus norvegicus)
RAB6A [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
RAB6A [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01968 OCRL
4
OCRL [Golgi membrane]
(R-HSA-434339)
OCRL [cytoplasmic vesicle membrane]
(R-HSA-434214)
OCRL [plasma membrane]
(R-HSA-3769049)
OCRL [cytosol]
(R-HSA-1806196)
0.875
14
UniProt:Q92871 PMM1
1
PMM1 [cytosol]
(R-HSA-532541)
0.666
4
UniProt:Q8IWJ2 GCC2
3
GCC2 [cytosol]
(R-HSA-6813880)
GCC2(1-1204)-p-7Y-ALK(1059-1620) fusion [cytosol]
(R-HSA-9713455)
GCC2(1-1204)-ALK(1059-1620) fusion [cytosol]
(R-HSA-9713458)
0.618
4
UniProt:P31150 GDI1
1
GDI1 [cytosol]
(R-HSA-195106)
0.527
3
UniProt:Q01968-2 OCRL
0.527
2
UniProt:Q8TD16 BICD2
1
BICD2 [cytosol]
(R-HSA-8848107)
0.463
3
ChEBI:16618 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE
0.462
2
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