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RAB6A [Golgi membrane]
Stable Identifier
R-HSA-1604442
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Pre-NOTCH Expression and Processing (Homo sapiens)
Pre-NOTCH Processing in Golgi (Homo sapiens)
Transport of NOTCH precursor to Golgi (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-independent Golgi-to-ER retrograde traffic (Homo sapiens)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Homo sapiens)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Homo sapiens)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Homo sapiens)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Homo sapiens)
RAB6:GTP:BICD dimer:COPI-independent retrograde cargo [Golgi membrane] (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
TBC/RABGAPs (Homo sapiens)
TBC1D11 binds RAB6 (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
RABGAP1:RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6:GTP [Golgi membrane] (Homo sapiens)
RAB6 [Golgi membrane] (Homo sapiens)
RAB6A [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20340 RAB6A
Gene Names
RAB6A, RAB6
Chain
initiator methionine:, chain:2-208
Reference Genes
BioGPS Gene:5870 RAB6A
COSMIC (genes):RAB6A RAB6A
CTD Gene:5870 RAB6A
dbSNP Gene:5870 RAB6A
ENSEMBL:ENSG00000175582 RAB6A
HGNC:9786 RAB6A
KEGG:hsa:5870 RAB6A
Monarch:5870 RAB6A
NCBI Gene:5870 RAB6A
OMIM:179513 RAB6A
UCSC:P20340 RAB6A
Reference Transcript
RefSeq:NM_002869.4 RAB6A
RefSeq:NM_001243719.1 RAB6A
RefSeq:NM_198896.1 RAB6A
RefSeq:NM_001243718.1 RAB6A
Participates
as a member of
RAB6 [Golgi membrane] (Homo sapiens)
This entity regulates
Positively
Transport of NOTCH precursor to Golgi
(Homo sapiens)
Other forms of this molecule
RAB6A [secretory granule membrane]
RAB6A [plasma membrane]
RAB6A [cytosol]
GGC-RAB6A [cytosol]
GGC-RAB6A [trans-Golgi network membrane]
RAB6A [trans-Golgi network membrane]
RAB6A [endoplasmic reticulum membrane]
Inferred To
RAB6A [Golgi membrane]
(Bos taurus)
RAB6A [Golgi membrane]
(Caenorhabditis elegans)
RAB6A [Golgi membrane]
(Dictyostelium discoideum)
RAB6A [Golgi membrane]
(Gallus gallus)
RAB6A [Golgi membrane]
(Mus musculus)
RAB6A [Golgi membrane]
(Plasmodium falciparum)
RAB6A [Golgi membrane]
(Rattus norvegicus)
RAB6A [Golgi membrane]
(Saccharomyces cerevisiae)
RAB6A [Golgi membrane]
(Schizosaccharomyces pombe)
Rab6 [Golgi membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002860.2
,
NP_942599.1
,
NP_001230647.1
,
NP_001230648.1
OpenTargets
ENSG00000175582
ENSEMBL
ENST00000310653
,
ENST00000541588
,
ENSP00000443782
,
ENST00000541973
,
ENSP00000336850
,
ENSP00000445350
,
ENSG00000175582
,
ENSP00000311449
,
ENST00000336083
HPA
ENSG00000175582-RAB6A
GeneCards
RAB6A
PRO
P20340
Pharos - Targets
P20340
GlyGen
P20340
PDB
2GIL
,
1YZQ
,
4DKX
,
3BBP
,
3CWZ
,
5LEF
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01968 OCRL
4
OCRL [Golgi membrane]
(R-HSA-434339)
OCRL [cytoplasmic vesicle membrane]
(R-HSA-434214)
OCRL [plasma membrane]
(R-HSA-3769049)
OCRL [cytosol]
(R-HSA-1806196)
0.875
14
UniProt:Q92871 PMM1
1
PMM1 [cytosol]
(R-HSA-532541)
0.666
4
UniProt:Q8IWJ2 GCC2
3
GCC2 [cytosol]
(R-HSA-6813880)
GCC2(1-1204)-p-7Y-ALK(1059-1620) fusion [cytosol]
(R-HSA-9713455)
GCC2(1-1204)-ALK(1059-1620) fusion [cytosol]
(R-HSA-9713458)
0.618
4
UniProt:Q01968-2 OCRL
0.527
2
UniProt:P31150 GDI1
1
GDI1 [cytosol]
(R-HSA-195106)
0.527
3
UniProt:Q8TD16 BICD2
1
BICD2 [cytosol]
(R-HSA-8848107)
0.463
3
ChEBI:16618 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE
0.462
2
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