Reactome | BICD2 [cytosol]

BICD2 [cytosol]

Stable Identifier

R-HSA-8848107

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Protein bicaudal D homolog 2, Bic-D 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8TD16 BICD2

Gene Names

BICD2, KIAA0699

Chain

initiator methionine:, chain:2-824

Reference Genes

BioGPS Gene:23299 BICD2

COSMIC (genes):BICD2 BICD2

CTD Gene:23299 BICD2

dbSNP Gene:23299 BICD2

ENSEMBL:ENSG00000185963 BICD2

HGNC:17208 BICD2

KEGG:hsa:23299 BICD2

Monarch:23299 BICD2

NCBI Gene:23299 BICD2

OMIM:609797 BICD2

UCSC:Q8TD16 BICD2

Reference Transcript

Participates

as a component of

BICD2 dimer [cytosol] (Homo sapiens)

Inferred To

bicd-1 [cytosol] (Caenorhabditis elegans)

BICD2 [cytosol] (Bos taurus)

BICD2 [cytosol] (Canis familiaris)

BICD2 [cytosol] (Gallus gallus)

BICD2 [cytosol] (Sus scrofa)

Bicd2 [cytosol] (Mus musculus)

Bicd2 [cytosol] (Rattus norvegicus)

BicD [cytosol] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000364662, ENSP00000349351, ENSG00000185963, ENST00000375512, ENST00000356884

OpenTargets

ENSG00000185963

GeneCards

BICD2

HPA

ENSG00000185963-BICD2

PRO

Q8TD16

Pharos - Targets

Q8TD16

Orphanet

BICD2

PDB

6OFP, 6PSE

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53350 PLK1	4	PLK1 [cytosol] (R-HSA-164603) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [nucleoplasm] (R-HSA-156720)	0.643	5
UniProt:P20340 RAB6A	8	RAB6A [Golgi membrane] (R-HSA-1604442) RAB6A [secretory granule membrane] (R-HSA-6804970) RAB6A [plasma membrane] (R-HSA-6804981) RAB6A [cytosol] (R-HSA-6810979) GGC-RAB6A [cytosol] (R-HSA-8874052) GGC-RAB6A [trans-Golgi network membrane] (R-HSA-8876079) RAB6A [trans-Golgi network membrane] (R-HSA-6810981) RAB6A [endoplasmic reticulum membrane] (R-HSA-8849253)	0.463	3