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UGT8 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-9844570
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Glycosphingolipid metabolism (Homo sapiens)
Glycosphingolipid biosynthesis (Homo sapiens)
UGT8 transfers Gal from UDP-Gal to CERA (Homo sapiens)
UGT8 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16880 UGT8
Gene Names
UGT8, CGT, UGT4
Chain
signal peptide:1-20, chain:21-541
Reference Genes
BioGPS Gene:7368 UGT8
COSMIC (genes):UGT8 UGT8
CTD Gene:7368 UGT8
dbSNP Gene:7368 UGT8
ENSEMBL:ENSG00000174607 UGT8
HGNC:12555 UGT8
KEGG:hsa:7368 UGT8
Monarch:7368 UGT8
NCBI Gene:7368 UGT8
OMIM:601291 UGT8
UCSC:Q16880 UGT8
Reference Transcript
RefSeq:NM_003360.4 UGT8
RefSeq:XM_047416133.1 UGT8
RefSeq:NM_001322113.2 UGT8
RefSeq:XM_047416134.1 UGT8
RefSeq:NM_001322114.2 UGT8
RefSeq:XM_024454210.2 UGT8
RefSeq:NM_001322112.2 UGT8
RefSeq:NM_001128174.3 UGT8
RefSeq:XM_047416135.1 UGT8
Other Identifiers
11739396_a_at
11746070_a_at
11759304_at
16970001
208358_PM_s_at
208358_s_at
228956_PM_at
228956_at
2660867
2740513
2740514
2740515
2740516
2740517
2740518
2740519
2740520
2740521
2740522
2740523
2740525
2740527
2740528
2740529
2740538
2740539
2740541
2740546
2740547
2740548
2740549
2740551
36363_at
45183_at
7368
8097017
A_14_P101214
A_24_P103264
A_24_P942589
GE62353
GE81268
GO:0002175
GO:0003851
GO:0005783
GO:0005789
GO:0006629
GO:0006665
GO:0006682
GO:0006688
GO:0007010
GO:0007399
GO:0007417
GO:0007422
GO:0008194
GO:0008489
GO:0009247
GO:0016020
GO:0016740
GO:0016757
GO:0016758
GO:0030913
GO:0034330
GO:0035902
GO:0048812
GO:0048856
GO:1901135
HMNXSV003010878
Hs.274293.0.S1_3p_at
ILMN_1758816
ILMN_2190292
PH_hs_0023371
TC04000590.hg
U30930_at
g4507826_3p_a_at
Inferred To
Ugt317A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-18 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-17 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt36A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-15 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-16 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-19 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt37B1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt49C1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-7 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-6 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-5 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt37C2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-4 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt37C1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-10 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-13 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-11 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-14 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-12 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt49B1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt37A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt50B3 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt302E1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt305A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-29 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-31 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-27 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt37A3 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-33 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-35 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-39 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-37 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-21 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-23 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-25 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt8 [endoplasmic reticulum membrane]
(Danio rerio)
Ugt37E1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-43 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-44 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-47 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt35B1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-40 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt8 [endoplasmic reticulum membrane]
(Mus musculus)
Ugt8 [endoplasmic reticulum membrane]
(Rattus norvegicus)
UGT8 [endoplasmic reticulum membrane]
(Bos taurus)
UGT8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
UGT8 [endoplasmic reticulum membrane]
(Canis familiaris)
UGT8 [endoplasmic reticulum membrane]
(Gallus gallus)
UGT8 [endoplasmic reticulum membrane]
(Sus scrofa)
ugt-48 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt36D1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt316A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-59 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-55 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-51 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt303A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-28 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-32 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt37A2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt49B2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-36 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-9 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-20 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-24 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt35E1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt35E2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt36F1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt303B1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt303B2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-61 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt303B3 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-60 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-67 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-66 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-64 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-65 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-62 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-63 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-56 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-54 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-52 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-50 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt35D1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-58 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-45 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-46 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt304A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-42 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-41 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt35C1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt302C1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-49 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt301D1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt36E1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Homologues of UGT8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of UGT8 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-53 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt35A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-30 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-26 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-34 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt302K1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-38 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
ugt-22 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Ugt307A1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Ugt37D1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
ugt-57 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001309042.2
,
NP_001309043.2
,
XP_024309978.1
,
XP_047272090.1
,
XP_047272091.1
,
NP_001309041.2
,
NP_001121646.2
,
NP_003351.2
,
XP_047272089.1
OpenTargets
ENSG00000174607
ENSEMBL
ENSP00000311648
,
ENSG00000174607
,
ENSP00000378019
,
ENST00000310836
,
ENST00000394511
IntEnz
2.4.1.47
HPA
ENSG00000174607-UGT8
GeneCards
UGT8
PRO
Q16880
Pharos - Targets
Q16880
GlyGen
Q16880
HMDB Protein
HMDBP01101
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13061 TRDN
1
TRDN [sarcoplasmic reticulum lumen]
(R-HSA-2855215)
0.643
4
UniProt:P19526 FUT1
1
FUT1 [Golgi membrane]
(R-HSA-9034059)
0.527
2
UniProt:P09601 HMOX1
4
HMOX1 [cytosol]
(R-HSA-9609901)
HMOX1 [endoplasmic reticulum membrane]
(R-HSA-189395)
HMOX1 [mitochondrial outer membrane]
(R-HSA-9708524)
HMOX1 [nucleoplasm]
(R-HSA-9708567)
0.527
3
UniProt:O75396 SEC22B
6
SEC22B [ER to Golgi transport vesicle membrane]
(R-HSA-5688565)
SEC22B [endoplasmic reticulum membrane]
(R-HSA-5688150)
SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688566)
SEC22B [phagocytic vesicle membrane]
(R-HSA-8863938)
SEC22B [transport vesicle]
(R-HSA-6810994)
SEC22B [Golgi membrane]
(R-HSA-6810993)
0.527
3
UniProt:P27824 CANX
3
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum membrane]
(R-HSA-9932989)
0.527
2
UniProt:Q8WWF1 CA054
0.527
3
UniProt:O14967 CLGN
0.527
2
UniProt:Q9UK22 FBXO2
1
FBXO2 [cytosol]
(R-HSA-976044)
0.527
3
UniProt:P05981 HPN
2
HPN(1-162) [plasma membrane]
(R-HSA-6800195)
HPN(163-417) [plasma membrane]
(R-HSA-8849219)
0.527
2
UniProt:P62502 LCN6
0.527
2
UniProt:P30519 HMOX2
3
HMOX2 [endoplasmic reticulum membrane]
(R-HSA-189391)
HMOX2 [specific granule membrane]
(R-HSA-6799628)
HMOX2 [plasma membrane]
(R-HSA-6799676)
0.527
3
UniProt:P28845 HSD11B1
1
HSD11B1 [endoplasmic reticulum membrane]
(R-HSA-193975)
0.527
2
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