Reactome | UGT8 [endoplasmic reticulum membrane]

UGT8 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9844570

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q16880 UGT8

Gene Names

UGT8, CGT, UGT4

Chain

signal peptide:1-20, chain:21-541

Reference Genes

BioGPS Gene:7368 UGT8

COSMIC (genes):UGT8 UGT8

CTD Gene:7368 UGT8

dbSNP Gene:7368 UGT8

ENSEMBL:ENSG00000174607 UGT8

ENSEMBL_homo_sapiens_GENE:ENSG00000174607.11 UGT8

HGNC:12555 UGT8

KEGG Gene (Homo sapiens):7368 UGT8

Monarch:7368 UGT8

NCBI Gene:7368 UGT8

OMIM:601291 UGT8

UCSC:Q16880 UGT8

Reference Transcript

Other Identifiers

11739396_a_at

11746070_a_at

11759304_at

16970001

208358_PM_s_at

208358_s_at

228956_PM_at

228956_at

2660867

2740514

2740515

2740516

2740527

2740528

2740529

2740538

2740539

2740541

2740546

2740547

2740548

2740549

2740551

36363_at

45183_at

7368

8097017

A_14_P101214

A_24_P103264

A_24_P942589

GE62353

GE81268

GO:0002175

GO:0003824

GO:0003851

GO:0005783

GO:0005886

GO:0006629

GO:0006665

GO:0006682

GO:0006688

GO:0007010

GO:0007417

GO:0007422

GO:0008194

GO:0008489

GO:0016020

GO:0016740

GO:0016757

GO:0030154

GO:0030913

GO:0034330

GO:0035902

GO:0043226

GO:0047263

GO:0048812

GO:0048856

GO:1901135

HMNXSV003010878

Hs.274293.0.S1_3p_at

ILMN_1758816

ILMN_2190292

PH_hs_0023371

TC04000590.hg

U30930_at

g4507826_3p_a_at

Inferred To

Ugt8 [endoplasmic reticulum membrane] (Mus musculus)

Ugt8 [endoplasmic reticulum membrane] (Rattus norvegicus)

UGT8 [endoplasmic reticulum membrane] (Bos taurus)

UGT8 [endoplasmic reticulum membrane] (Canis familiaris)

UGT8 [endoplasmic reticulum membrane] (Gallus gallus)

UGT8 [endoplasmic reticulum membrane] (Sus scrofa)

ugt-60 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

ugt8 [endoplasmic reticulum membrane] (Danio rerio)

Cross References

RefSeq

NP_001121646.1, NP_001309042.1, NP_003351.2, NP_001309043.1, NP_001309041.1

OpenTargets

ENSG00000174607

IntEnz

2.4.1.47

GeneCards

Q16880

HPA

ENSG00000174607-UGT8

Ensembl

ENSP00000378019, ENST00000394511, ENSG00000174607, ENST00000310836, ENSP00000311648

PRO

Q16880

Pharos - Targets

Q16880

HMDB Protein

HMDBP01101

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.527	3
UniProt:P28845 HSD11B1	1	HSD11B1 [endoplasmic reticulum membrane] (R-HSA-193975)	0.527	2
UniProt:Q13061 TRDN	1	TRDN [sarcoplasmic reticulum lumen] (R-HSA-2855215)	0.527	3
UniProt:P30519 HMOX2	3	HMOX2 [plasma membrane] (R-HSA-6799676) HMOX2 [specific granule membrane] (R-HSA-6799628) HMOX2 [endoplasmic reticulum membrane] (R-HSA-189391)	0.527	3
UniProt:P09601 HMOX1	4	HMOX1 [nucleoplasm] (R-HSA-9708567) HMOX1 [mitochondrial outer membrane] (R-HSA-9708524) HMOX1 [endoplasmic reticulum membrane] (R-HSA-189395) HMOX1 [cytosol] (R-HSA-9609901)	0.527	3
UniProt:P19526 FUT1	1	FUT1 [Golgi membrane] (R-HSA-9034059)	0.527	2
UniProt:P27824 CANX	2	CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.527	2

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