Reactome | NCR3LG1 [plasma membrane]

NCR3LG1 [plasma membrane]

Stable Identifier

R-HSA-5683240

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Natural cytotoxicity triggering receptor 3 ligand 1, NR3L1_HUMAN, B7H6

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q68D85 NCR3LG1

Gene Names

NCR3LG1, B7H6

Chain

signal peptide:1-24, chain:25-454

Reference Genes

BioGPS Gene:374383 NCR3LG1

COSMIC (genes):NCR3LG1 NCR3LG1

CTD Gene:374383 NCR3LG1

dbSNP Gene:374383 NCR3LG1

ENSEMBL:ENSG00000188211 NCR3LG1

ENSEMBL_homo_sapiens_GENE:ENSG00000188211.9 NCR3LG1

HGNC:42400 NCR3LG1

KEGG Gene (Homo sapiens):374383 NCR3LG1

Monarch:374383 NCR3LG1

NCBI Gene:374383 NCR3LG1

OMIM:613714 NCR3LG1

UCSC:Q68D85 NCR3LG1

Reference Transcript

RefSeq:NM_001202439.2 NCR3LG1

Other Identifiers

16722445

16722455

229715_PM_at

229715_at

3322309

3322315

3322316

3322318

3322320

3322321

3322322

3322323

3322324

3322325

3322326

3322327

3322328

374383

43752_at

46881_at

7938702

89122_s_at

A_19_P00329765

A_21_P0007429

A_32_P2050

A_33_P3356210

GE85440

GO:0002376

GO:0003823

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0006958

GO:0016020

GO:0019731

GO:0034987

GO:0042571

GO:0098542

HMNXSV003014129

HMNXSV003024501

HMNXSV003041773

Hs.146274.0.S1_3p_at

ILMN_1669972

ILMN_1883404

PH_hs_0036098

TC11000229.hg

TC11002578.hg

TC11002579.hg

p18424

Participates

as a component of

NCR3LG1:NCR3:FCRG3A:CD3Z dimer [plasma membrane] (Homo sapiens)

as an input of

NCR3LG1 binds NCR3 (Homo sapiens)

Inferred To

NCR3LG1 [plasma membrane] (Bos taurus)

NCR3LG1 [plasma membrane] (Canis familiaris)

Cross References

RefSeq

NP_001189368.1

OpenTargets

ENSG00000188211

HPA

ENSG00000188211-NCR3LG1

GeneCards

Q68D85

Ensembl

ENSP00000341637, ENST00000338965, ENSG00000188211, ENSP00000434394, ENST00000530403

PRO

Q68D85

Pharos - Targets

Q68D85

PDB

4ZSO, 6YJP, 3PV7, 3PV6

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14931 NCR3	1	NCR3 [plasma membrane] (R-HSA-5683241)	0.931	16
UniProt:Q9UKR5 ERG28			0.556	3
UniProt:Q8N912 NRAC			0.556	3
UniProt:P29400-2 COL4A5			0.556	3
UniProt:Q8IY26 PLPP6	1	PLPP6 [plasma membrane] (R-HSA-8952144)	0.556	3
UniProt:Q9UNK0 STX8			0.556	3
UniProt:Q5BVD1 TTMP			0.556	3
UniProt:P30536 TSPO	1	TSPO [mitochondrial outer membrane] (R-HSA-2980957)	0.556	3
UniProt:Q9P0S9 TM14C			0.556	3
UniProt:Q9H0R3 TM222			0.556	3
UniProt:A8MVW0 F1712			0.527	2
UniProt:Q96QU8 XPO6			0.527	2
UniProt:Q96S97 MYADM			0.527	3
UniProt:O96008 TOMM40	3	TOMM40 [mitochondrial intermembrane space] (R-HSA-1267971) TOMM40 [cytosol] (R-HSA-1267992) TOMM40 [mitochondrial outer membrane] (R-HSA-1252082)	0.527	3
UniProt:Q6ZRQ5 MMS22			0.527	2
UniProt:Q9HAV4 XPO5	2	XPO5 [cytosol] (R-HSA-847719) XPO5 [nucleoplasm] (R-HSA-847721)	0.527	3
UniProt:P36404 ARL2	2	ARL2 [cytosol] (R-HSA-5216230) ARL2 [mitochondrial matrix] (R-HSA-5250216)	0.527	2
UniProt:P34925 RYK	1	RYK [plasma membrane] (R-HSA-3006746)	0.527	3
UniProt:O15121 DEGS1	3	DEGS1 [plasma membrane] (R-HSA-6806305) DEGS1 [specific granule membrane] (R-HSA-6799512) DEGS1 [endoplasmic reticulum membrane] (R-HSA-428201)	0.527	2
UniProt:Q13535 ATR	1	ATR [nucleoplasm] (R-HSA-912443)	0.527	2
UniProt:O15431 SLC31A1	1	SLC31A1 [plasma membrane] (R-HSA-437299)	0.527	2
UniProt:Q96E52 OMA1	3	OMA1(144-447) [mitochondrial inner membrane] (R-HSA-9840539) OMA1(144-524) [mitochondrial inner membrane] (R-HSA-9840540) OMA1 [mitochondrial inner membrane] (R-HSA-8867510)	0.527	2
UniProt:P47813 EIF1AX	1	EIF1AX [cytosol] (R-HSA-72557)	0.527	2

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