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OMA1 [mitochondrial inner membrane]
Stable Identifier
R-HSA-8867510
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Metalloendopeptidase OMA1, mitochondrial ecNumber3.4.24.-/ecNumber, OMA1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Mitochondrial protein degradation (Homo sapiens)
YME1L1 binds mitochondrial inner membrane proteins (Homo sapiens)
Substrate of YME1L1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
OMA1 [mitochondrial inner membrane] (Homo sapiens)
YME1L1:substrate protein (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
Substrate of YME1L1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
OMA1 [mitochondrial inner membrane] (Homo sapiens)
YME1L1 degrades mitochondrial inner membrane proteins (Homo sapiens)
YME1L1:substrate protein (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
Substrate of YME1L1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
OMA1 [mitochondrial inner membrane] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Regulation of Apoptosis (Homo sapiens)
OMA1 hydrolyses OPA1 (Homo sapiens)
OMA1:Zn2+ [mitochondrial inner membrane] (Homo sapiens)
OMA1 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96E52 OMA1
Gene Names
OMA1, MPRP1
Chain
transit peptide:1-13, propeptide:14-143, chain:144-, propeptide:-524
Reference Genes
BioGPS Gene:115209 OMA1
COSMIC (genes):OMA1 OMA1
CTD Gene:115209 OMA1
dbSNP Gene:115209 OMA1
ENSEMBL:ENSG00000162600 OMA1
HGNC:29661 OMA1
KEGG:hsa:115209 OMA1
Monarch:115209 OMA1
NCBI Gene:115209 OMA1
UCSC:Q96E52 OMA1
Reference Transcript
RefSeq:NM_145243.4 OMA1
Other Identifiers
115209
11731585_a_at
16687829
226019_PM_at
226019_at
226020_PM_s_at
226020_s_at
2414734
2414739
2414741
2414743
2414745
2414746
2414747
2414748
2414749
2414759
2414760
2414764
2414765
2414767
2414768
2414769
2414770
2414771
2414772
2414773
2414774
2414775
2414777
2414778
2414780
2414781
42861_at
48617_at
7916570
A_19_P00803169
A_23_P138137
A_23_P138139
GE79354
GO:0002024
GO:0003824
GO:0004222
GO:0005739
GO:0005743
GO:0005758
GO:0005975
GO:0006006
GO:0006508
GO:0006515
GO:0006629
GO:0007005
GO:0008237
GO:0008289
GO:0010637
GO:0016020
GO:0016540
GO:0016787
GO:0031638
GO:0031966
GO:0033108
GO:0034982
GO:0042407
GO:0043065
GO:0043226
GO:0046872
GO:0051604
GO:0061024
GO:0065003
GO:0097009
GO:0120162
GO:0140096
GO:0140467
GO:0140468
GO:1903850
HMNXSV003017064
Hs.8108.1.S1_3p_at
ILMN_1670079
ILMN_2094938
PH_hs_0000866
PH_hs_0035337
TC01005518.hg
p25647
Participates
as a member of
Substrate of YME1L1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
as a component of
OMA1:Zn2+ [mitochondrial inner membrane] (Homo sapiens)
Other forms of this molecule
OMA1(144-447) [mitochondrial inner membrane]
OMA1(144-524) [mitochondrial inner membrane]
Inferred To
OMA1 [mitochondrial inner membrane]
(Bos taurus)
OMA1 [mitochondrial inner membrane]
(Canis familiaris)
OMA1 [mitochondrial inner membrane]
(Danio rerio)
OMA1 [mitochondrial inner membrane]
(Dictyostelium discoideum)
OMA1 [mitochondrial inner membrane]
(Gallus gallus)
OMA1 [mitochondrial inner membrane]
(Mus musculus)
OMA1 [mitochondrial inner membrane]
(Rattus norvegicus)
OMA1 [mitochondrial inner membrane]
(Saccharomyces cerevisiae)
OMA1 [mitochondrial inner membrane]
(Schizosaccharomyces pombe)
OMA1 [mitochondrial inner membrane]
(Sus scrofa)
oma1 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000360270
,
ENST00000371226
,
ENSG00000162600
OpenTargets
ENSG00000162600
GeneCards
OMA1
HPA
ENSG00000162600-OMA1
PRO
Q96E52
Pharos - Targets
Q96E52
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q68D85 NCR3LG1
1
NCR3LG1 [plasma membrane]
(R-HSA-5683240)
0.527
2
UniProt:P46059 SLC15A1
1
SLC15A1 [plasma membrane]
(R-HSA-428022)
0.527
2
UniProt:A1L190 SYCE3
1
SYCE3 [nucleoplasm]
(R-HSA-8867779)
0.527
2
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