Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NCR3 [plasma membrane]
Stable Identifier
R-HSA-5683241
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Natural cytotoxicity triggering receptor 3, NCTR3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
CMVPP65 binds NCR3 (Homo sapiens)
CMVPP65:NCR3:FCRG3A:CD3Z dimer [plasma membrane] (Homo sapiens)
NCR3:FCRG1A:CD3Z dimer [plasma membrane] (Homo sapiens)
NCR3 [plasma membrane] (Homo sapiens)
NCR3:FCRG1A:CD3Z dimer [plasma membrane] (Homo sapiens)
NCR3 [plasma membrane] (Homo sapiens)
NCR3LG1 binds NCR3 (Homo sapiens)
NCR3:FCRG1A:CD3Z dimer [plasma membrane] (Homo sapiens)
NCR3 [plasma membrane] (Homo sapiens)
NCR3LG1:NCR3:FCRG3A:CD3Z dimer [plasma membrane] (Homo sapiens)
NCR3:FCRG1A:CD3Z dimer [plasma membrane] (Homo sapiens)
NCR3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14931 NCR3
Gene Names
NCR3, 1C7, LY117
Chain
signal peptide:1-18, chain:19-201
Reference Genes
BioGPS Gene:259197 NCR3
COSMIC (genes):NCR3 NCR3
CTD Gene:259197 NCR3
dbSNP Gene:259197 NCR3
ENSEMBL:ENSG00000204475 NCR3
HGNC:19077 NCR3
KEGG:hsa:259197 NCR3
Monarch:259197 NCR3
NCBI Gene:259197 NCR3
OMIM:611550 NCR3
UCSC:O14931 NCR3
Reference Transcript
RefSeq:XM_054331032.1 NCR3
RefSeq:XM_054328461.1 NCR3
RefSeq:XM_011514459.3 NCR3
RefSeq:XM_054330544.1 NCR3
RefSeq:NM_001145466.2 NCR3
RefSeq:XM_054330252.1 NCR3
RefSeq:XM_054329761.1 NCR3
RefSeq:XM_054355125.1 NCR3
RefSeq:XM_054331031.1 NCR3
RefSeq:XM_054355122.1 NCR3
RefSeq:XM_054331294.1 NCR3
RefSeq:XM_054330251.1 NCR3
RefSeq:NM_001145467.2 NCR3
RefSeq:NM_147130.3 NCR3
RefSeq:XM_054330794.1 NCR3
RefSeq:XM_054328462.1 NCR3
RefSeq:XM_054330543.1 NCR3
RefSeq:XM_006715049.4 NCR3
RefSeq:XM_054331291.1 NCR3
RefSeq:XM_054329764.1 NCR3
Participates
as a component of
NCR3:FCRG1A:CD3Z dimer [plasma membrane] (Homo sapiens)
Inferred To
NCR3 [plasma membrane]
(Bos taurus)
NCR3 [plasma membrane]
(Canis familiaris)
NCR3 [plasma membrane]
(Sus scrofa)
Ncr3 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_667341.1
,
NP_001138938.1
,
XP_054186519.1
,
XP_011512761.1
,
XP_054187266.1
,
NP_001138939.1
,
XP_054187006.1
,
XP_054187269.1
,
XP_054211100.1
,
XP_054186769.1
,
XP_054187007.1
,
XP_054184436.1
,
XP_006715112.1
,
XP_054185739.1
,
XP_054185736.1
,
XP_054184437.1
,
XP_054211097.1
,
XP_054186226.1
,
XP_054186518.1
,
XP_054186227.1
Guide to Pharmacology - Targets
3141
OpenTargets
ENSG00000204475
ENSEMBL
ENST00000439584
,
ENSP00000372969
,
ENSP00000372968
,
ENSP00000404747
,
ENSP00000342156
,
ENST00000419086
,
ENSG00000225211
,
ENSP00000416105
,
ENSP00000412702
,
ENSP00000416944
,
ENSP00000365240
,
ENST00000412603
,
ENSP00000365241
,
ENSP00000389396
,
ENSP00000409874
,
ENSG00000223833
,
ENST00000420556
,
ENST00000446756
,
ENSP00000389071
,
ENST00000383478
,
ENST00000383476
,
ENST00000457547
,
ENSG00000236979
,
ENST00000376071
,
ENSP00000391177
,
ENST00000435674
,
ENST00000436623
,
ENST00000438663
,
ENST00000433654
,
ENSP00000412474
,
ENST00000376072
,
ENSP00000372970
,
ENSP00000395238
,
ENSG00000237103
,
ENSP00000403978
,
ENSP00000383100
,
ENSP00000415456
,
ENSG00000206430
,
ENSP00000409048
,
ENSP00000408960
,
ENSP00000399128
,
ENSP00000398313
,
ENSP00000415697
,
ENSP00000390131
,
ENST00000430599
,
ENST00000453657
,
ENSG00000237808
,
ENSG00000204475
,
ENSP00000405306
,
ENST00000400241
,
ENST00000447248
,
ENST00000420485
,
ENSP00000389419
,
ENST00000419728
,
ENST00000418936
,
ENST00000455825
,
ENSG00000236315
,
ENST00000436253
,
ENST00000383477
,
ENST00000455448
,
ENST00000452296
,
ENSP00000402904
,
ENSP00000406373
,
ENST00000441372
,
ENSP00000365239
,
ENST00000340027
,
ENST00000437517
,
ENST00000376073
,
ENST00000432392
,
ENSP00000416035
,
ENSP00000411205
,
ENST00000415123
GeneCards
NCR3
HPA
ENSG00000204475-NCR3
PRO
O14931
Pharos - Targets
O14931
GlyGen
O14931
PDB
3NOI
,
6YJP
,
9FWW
,
3PV6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q68D85 NCR3LG1
1
NCR3LG1 [plasma membrane]
(R-HSA-5683240)
0.956
18
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text