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PLPP6 [plasma membrane]
Stable Identifier
R-HSA-8952144
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Phospholipid phosphatase 6, PLPP6_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Cholesterol biosynthesis (Homo sapiens)
Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Homo sapiens)
PLPP6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IY26 PLPP6
Gene Names
PLPP6, PDP1, PPAPDC2
Chain
chain:1-295
Reference Genes
BioGPS Gene:403313 PLPP6
COSMIC (genes):PDP1 PLPP6
COSMIC (genes):PLPP6 PLPP6
CTD Gene:403313 PLPP6
dbSNP Gene:403313 PLPP6
ENSEMBL:ENSG00000205808 PLPP6
HGNC:23682 PLPP6
KEGG:hsa:403313 PLPP6
Monarch:403313 PLPP6
NCBI Gene:403313 PLPP6
OMIM:611666 PLPP6
UCSC:Q8IY26 PLPP6
Reference Transcript
RefSeq:NM_203453.3 PLPP6
Other Identifiers
11743337_at
11751580_a_at
17083277
227385_PM_at
227385_at
3160728
3160729
3160730
3160731
3160733
3160734
403313
44523_at
51170_at
8154151
A_24_P40907
GE88289
GO:0002376
GO:0003824
GO:0005515
GO:0005634
GO:0005635
GO:0005637
GO:0005783
GO:0005789
GO:0005886
GO:0006629
GO:0006695
GO:0006720
GO:0008195
GO:0016020
GO:0016787
GO:0016829
GO:0018342
GO:0031965
GO:0033383
GO:0042392
GO:0042577
GO:0043226
GO:0045087
GO:0045339
GO:0046839
GO:0052642
GO:0098542
GO:0106405
GO:1902247
GO:1902565
HMNXSV003030623
Hs.29669.0.A1_3p_at
ILMN_1802628
PH_hs_0002565
TC09000030.hg
Inferred To
Dmel\CG31717 [plasma membrane]
(Drosophila melanogaster)
Plpp6 [plasma membrane]
(Mus musculus)
Plpp6 [plasma membrane]
(Rattus norvegicus)
CAX4 [plasma membrane]
(Saccharomyces cerevisiae)
PLPP6 [plasma membrane]
(Bos taurus)
PLPP6 [plasma membrane]
(Caenorhabditis elegans)
PLPP6 [plasma membrane]
(Canis familiaris)
PLPP6 [plasma membrane]
(Dictyostelium discoideum)
PLPP6 [plasma membrane]
(Gallus gallus)
PLPP6 [plasma membrane]
(Sus scrofa)
plpp6 [plasma membrane]
(Danio rerio)
plpp6 [plasma membrane]
(Xenopus tropicalis)
Cross References
OpenTargets
ENSG00000205808
ENSEMBL
ENST00000381883
,
ENSP00000371307
IntEnz
3.6.1.68
HPA
ENSG00000205808-PLPP6
PRO
Q8IY26
Pharos - Targets
Q8IY26
HMDB Protein
HMDBP07321
Interactors (55)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H2X3 CLEC4M
1
CLEC4M [plasma membrane]
(R-HSA-1472862)
0.556
3
UniProt:Q96LL3 FIMP
0.556
3
UniProt:Q8TBG9 SYNPR
0.556
3
UniProt:Q96KR7 PHAR3
0.556
3
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:Q5T700 LRAD1
0.556
3
UniProt:Q96KR6 F210B
0.556
3
UniProt:Q14802-3 FXYD3
0.556
3
UniProt:Q6UX15-2 Q6UX152
0.556
3
UniProt:P15941-11 MUC1
0.556
3
UniProt:Q8TBP5 F174A
0.556
3
UniProt:Q14627 IL13RA2
1
IL13RA2 [extracellular region]
(R-HSA-449666)
0.556
3
UniProt:Q13651 IL10RA
3
p-Y446-IL10RA [plasma membrane]
(R-HSA-6784810)
p-Y496-IL10RA [plasma membrane]
(R-HSA-6784793)
IL10RA [plasma membrane]
(R-HSA-449841)
0.556
3
UniProt:P21964 COMT
2
COMT [cytosol]
(R-HSA-175974)
COMT [plasma membrane]
(R-HSA-379386)
0.556
3
UniProt:Q68D85 NCR3LG1
1
NCR3LG1 [plasma membrane]
(R-HSA-5683240)
0.556
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q8N4V1 MMGT1
1
MMGT1 [Golgi membrane]
(R-HSA-5216137)
0.556
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
5
UniProt:P16471 PRLR
3
p-Y611-PRLR [plasma membrane]
(R-HSA-1369104)
PRLR [plasma membrane]
(R-HSA-976964)
p-Y611-PRLR [endosome lumen]
(R-HSA-2002376)
0.556
3
UniProt:Q9UBN6 TNFRSF10D
1
TNFRSF10D [plasma membrane]
(R-HSA-5633374)
0.556
3
UniProt:P15151 PVR
1
PVR [plasma membrane]
(R-HSA-420600)
0.556
3
UniProt:P16234-2 PDGFRA
0.556
3
UniProt:Q96K19-5 RNF170
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
IntAct:EBI-22344578 CCSB ORF ID
0.556
3
UniProt:Q96FX9 Q96FX9
0.556
3
UniProt:Q9BY50 SEC11C
1
SEC11C [endoplasmic reticulum membrane]
(R-HSA-265065)
0.556
3
UniProt:Q5T7V8 GORAB
0.556
3
UniProt:Q9BVX2 T106C
0.556
3
UniProt:Q99942 RNF5
1
RNF5 [endoplasmic reticulum membrane]
(R-HSA-975990)
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:Q6UXG8-3 Q6UXG83
0.556
3
UniProt:Q8TBB6 S7A14
0.556
3
UniProt:Q8N6L0 KASH5
0.556
3
UniProt:Q13113 PDZ1I
0.556
3
UniProt:Q8WWF3 SSMM1
0.556
3
UniProt:O95484 CLDN9
2
CLDN9 [plasma membrane]
(R-HSA-420016)
CLDN9 [cell junction]
(R-HSA-421271)
0.556
3
UniProt:Q8TBE3 FNDC9
0.556
3
UniProt:Q86WK6 AMGO1
0.556
3
UniProt:Q96HJ5 MS4A3
2
MS4A3 [plasma membrane]
(R-HSA-6806321)
MS4A3 [specific granule membrane]
(R-HSA-6799514)
0.556
3
UniProt:Q9H5X1 CIA2A
0.556
3
UniProt:Q86VR2 RETR3
0.556
3
UniProt:Q9NS71 GKN1
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q0VAQ4 SMAGP
0.556
3
UniProt:O95377 GJB5
1
GJB5 [endoplasmic reticulum membrane]
(R-HSA-190643)
0.556
3
UniProt:O75503 CLN5
0.556
3
UniProt:Q7KYR7-4 Q7KYR74
0.556
3
UniProt:Q96PQ1 SIGLEC12
1
SIGLEC12 [plasma membrane]
(R-HSA-197729)
0.556
3
UniProt:Q8N205-2 SYNE4
0.556
3
UniProt:Q9Y680 FKBP7
0.556
3
UniProt:Q3SXP7 SHSL1
0.556
3
UniProt:Q9H7M9 VISTA
0.556
3
UniProt:O94778 AQP8
2
AQP8 [plasma membrane]
(R-HSA-431756)
AQP8 [mitochondrial inner membrane]
(R-HSA-3779402)
0.556
3
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