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RYK [plasma membrane]
Stable Identifier
R-HSA-3006746
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Tyrosine-protein kinase RYK ecNumber2.7.10.1/ecNumber, RYK_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
PCP/CE pathway (Homo sapiens)
RYK binds WNT5A and VANGL2 (Homo sapiens)
N4GlycoAsn-PalmS-WNT5A:RYK:VANGL2 [plasma membrane] (Homo sapiens)
RYK [plasma membrane] (Homo sapiens)
RYK [plasma membrane] (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Canonical WNT signaling through the atypical receptor RYK (Homo sapiens)
RYK [plasma membrane] (Homo sapiens)
RYK:WNTs [plasma membrane] (Homo sapiens)
RYK [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P34925 RYK
Gene Names
RYK, JTK5A
Chain
signal peptide:1-25, chain:26-607
Reference Genes
BioGPS Gene:6259 RYK
CTD Gene:6259 RYK
dbSNP Gene:6259 RYK
ENSEMBL:ENSG00000163785 RYK
ENSEMBL_homo_sapiens_GENE:ENSG00000163785 RYK
HGNC:10481 RYK
KEGG Gene (Homo sapiens):6259 RYK
Monarch:6259 RYK
NCBI Gene:6259 RYK
OMIM:600524 RYK
Reference Transcript
RefSeq:NM_001005861.2 RYK
RefSeq:NM_002958.3 RYK
Other Identifiers
0000070592
11740589_s_at
16959412
202853_s_at
214172_x_at
216976_s_at
2696255
2696256
2696257
2696258
2696261
2696262
2696264
2696267
2696269
2696271
2696272
2696279
2696280
2696281
2696282
2696287
2696292
2696293
34117
3706890
3706892
3706895
3706896
3706898
45503
539_at
6259
75430
8090840
A0A0D9SFZ4
A_24_P229377
A_33_P3379371
AAB26341
AC096967
AC107310
AC108742
AMYH02007719
CAA49591
CAA65406
CCDS75016
CCDS77820
ENSG00000163785
ENSP00000478721
ENSP00000485095
ENST00000620660
ENST00000623711
EntrezGene:6259
g11863158_3p_a_at
g11863158_3p_x_at
GE58784
GO:0000166
GO:0000902
GO:0003674
GO:0004888
GO:0005109
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005886
GO:0005887
GO:0006464
GO:0007165
GO:0007267
GO:0007409
GO:0007411
GO:0007416
GO:0008150
GO:0008219
GO:0008283
GO:0009968
GO:0016020
GO:0016021
GO:0016055
GO:0016301
GO:0016310
GO:0016740
GO:0017147
GO:0018108
GO:0022008
GO:0022038
GO:0022607
GO:0030154
GO:0030182
GO:0031175
GO:0032991
GO:0033278
GO:0035567
GO:0036518
GO:0040007
GO:0040011
GO:0042813
GO:0043066
GO:0043167
GO:0043226
GO:0043235
GO:0043410
GO:0048705
GO:0048843
GO:0048856
GO:0050919
GO:0060070
GO:0070374
GO:0071679
GO:1904929
GO:1904938
GO:1904948
GO:1904953
H0Y8A4
HGNC:10481
HPA045503
HPA075430
Hs.79350.2.S1_3p_a_at
ILMN_1658526
ILMN_1769671
ILMN_1798465
ILMN_2363439
IPR000719
IPR001245
IPR003306
IPR008266
IPR011009
IPR038677
MIM:600524
NM_001005861
NM_002958
NP_001005861
NP_002949
PF02019
PF07714
PH_hs_0040130
PR00109
RYK
RYK-208
RYK-209
S59184
S59184_at
SM00469
TC03003415.hg
uc032sdg.2
uc032sdh.1
UPI0000451C9C
UPI0000451C9D
X69970
X96588
XR_924160
Participant Of
input
Canonical WNT signaling through the atypical receptor RYK
RYK binds WNT5A and VANGL2
Wnt5a binds RYK and VANGL2
hasComponent
N4GlycoAsn-PalmS-WNT5A:RYK:VANGL2 [plasma membrane]
N4GlycoAsn-PalmS-Wnt5a:RYK:VANGL2 [plasma membrane]
RYK:WNTs [plasma membrane]
Inferred To
RYK [plasma membrane] (Bos taurus)
RYK [plasma membrane] (Caenorhabditis elegans)
RYK [plasma membrane] (Canis familiaris)
RYK [plasma membrane] (Danio rerio)
RYK [plasma membrane] (Drosophila melanogaster)
RYK [plasma membrane] (Gallus gallus)
RYK [plasma membrane] (Mus musculus)
RYK [plasma membrane] (Rattus norvegicus)
RYK [plasma membrane] (Sus scrofa)
RYK [plasma membrane] (Taeniopygia guttata)
RYK [plasma membrane] (Xenopus tropicalis)
Homologues of RYK [plasma membrane] (Danio rerio)
Homologues of RYK [plasma membrane] (Drosophila melanogaster)
Homologues of RYK [plasma membrane] (Sus scrofa)
Homologues of RYK [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_002949.2
,
NP_001005861.1
OpenTargets
ENSG00000163785
GeneCards
P34925
PRO
P34925
BRENDA (Homo sapiens)
2.7.10.1
HMDB Protein
HMDBP01453
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